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Protein

Peptide chain release factor 1

Gene

prfA

Organism
Rhizobium leguminosarum bv. viciae (strain 3841)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.UniRule annotation

GO - Molecular functioni

Keywordsi

Biological processProtein biosynthesis

Names & Taxonomyi

Protein namesi
Recommended name:
Peptide chain release factor 1UniRule annotation
Short name:
RF-1UniRule annotation
Gene namesi
Name:prfAUniRule annotation
Ordered Locus Names:RL4282
OrganismiRhizobium leguminosarum bv. viciae (strain 3841)
Taxonomic identifieri216596 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhizobialesRhizobiaceaeRhizobium/Agrobacterium groupRhizobium
Proteomesi
  • UP000006575 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002633301 – 359Peptide chain release factor 1Add BLAST359

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei235N5-methylglutamineUniRule annotation1

Post-translational modificationi

Methylated by PrmC. Methylation increases the termination efficiency of RF1.UniRule annotation

Keywords - PTMi

Methylation

Proteomic databases

PRIDEiQ1MBB2

Interactioni

Protein-protein interaction databases

STRINGi216596.RL4282

Structurei

3D structure databases

ProteinModelPortaliQ1MBB2
SMRiQ1MBB2
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the prokaryotic/mitochondrial release factor family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105C8K Bacteria
COG0216 LUCA
HOGENOMiHOG000074815
KOiK02835
OMAiWKVEIVS
OrthoDBiPOG091H021P

Family and domain databases

HAMAPiMF_00093 Rel_fac_1, 1 hit
InterProiView protein in InterPro
IPR005139 PCRF
IPR000352 Pep_chain_release_fac_I_II
IPR004373 PrfA
PfamiView protein in Pfam
PF03462 PCRF, 1 hit
PF00472 RF-1, 1 hit
SMARTiView protein in SMART
SM00937 PCRF, 1 hit
TIGRFAMsiTIGR00019 prfA, 1 hit
PROSITEiView protein in PROSITE
PS00745 RF_PROK_I, 1 hit

Sequencei

Sequence statusi: Complete.

Q1MBB2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAKLPVEKMR ELERRFGEIE ARMSAGPAAD VYVKLASEYS ELQPVVTKIR
60 70 80 90 100
VYEKAVTELA DLETLLEDRS VDREMRDLAE LELPEVKEQI EALEQEMQIL
110 120 130 140 150
LLPKDAADEK SAILEIRAGT GGSEAALFAG DLFRMYERFA AEKGWKVEVL
160 170 180 190 200
SASEGEAGGY KEIIATITGK GVFAKLKFES GVHRVQRVPE TEAGGRIHTS
210 220 230 240 250
AATVAVLPEA EEIDIEIRAE DIRIDTMRSS GAGGQHVNTT DSAVRITHLP
260 270 280 290 300
SGIVVTSSEK SQHQNRAKAM QVLRSRLYDA ERQRADSERS ADRKSQVGSG
310 320 330 340 350
DRSERIRTYN FPQGRVTDHR INLTLYKLDR MMEGEIEEVV DALMADYQAS

QLAQLGEQQ
Length:359
Mass (Da):39,995
Last modified:May 30, 2006 - v1
Checksum:i56C6308EB9D1E44B
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AM236080 Genomic DNA Translation: CAK09771.1
RefSeqiWP_011653677.1, NC_008380.1

Genome annotation databases

EnsemblBacteriaiCAK09771; CAK09771; RL4282
KEGGirle:RL4282

Similar proteinsi

Entry informationi

Entry nameiRF1_RHIL3
AccessioniPrimary (citable) accession number: Q1MBB2
Entry historyiIntegrated into UniProtKB/Swiss-Prot: December 12, 2006
Last sequence update: May 30, 2006
Last modified: May 23, 2018
This is version 77 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome
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Main funding by: National Institutes of Health