Skip Header

Contribute Send feedback
Read comments (?) or add your own

Q1MB46 (AROB_RHIL3) Reviewed, UniProtKB/Swiss-Prot

Last modified January 25, 2012. Version 40. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
3-dehydroquinate synthase
EC=4.2.3.4
Gene names
Name:aroB
Ordered Locus Names:RL4352
OrganismRhizobium leguminosarum bv. viciae (strain 3841) [Complete proteome] [HAMAP]
Taxonomic identifier216596 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Alphaproteobacteria › Rhizobiales › Rhizobiaceae › Rhizobium/Agrobacterium group › Rhizobium

Protein attributes

Sequence length376 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

3-deoxy-D-arabino-hept-2-ulosonate 7-phosphate = 3-dehydroquinate + phosphate. HAMAP MF_00110

Cofactor

Divalent metal cations By similarity. HAMAP MF_00110

NAD By similarity. HAMAP MF_00110

Pathway

Metabolic intermediate biosynthesis; chorismate biosynthesis; chorismate from D-erythrose 4-phosphate and phosphoenolpyruvate: step 2/7. HAMAP MF_00110

Subunit structure

Monomer By similarity. HAMAP MF_00110

Subcellular location

Cytoplasm By similarity HAMAP MF_00110.

Sequence similarities

Belongs to the dehydroquinate synthase family.

Ontologies

Keywords
   Biological processAmino-acid biosynthesis
Aromatic amino acid biosynthesis
   Cellular componentCytoplasm
   LigandNAD
   Molecular functionLyase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processaromatic amino acid family biosynthetic process

Inferred from electronic annotation. Source: UniProtKB-KW

   Cellular componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular function3-dehydroquinate synthase activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 3763763-dehydroquinate synthase HAMAP MF_00110
PRO_1000094583

Sequences

Sequence LengthMass (Da)Tools
Q1MB46 [UniParc].

Last modified May 30, 2006. Version 1.
Checksum: AE23684597D8BA11

FASTA37640,053
        10         20         30         40         50         60 
MNAITSASAI RTVHVPLGER AYDILIGPGL IARAGAEIAS RLKGRKAAVV TDENVAPLYL 

        70         80         90        100        110        120 
KALVASLDEA GIASAEVVLP AGEKTKSFEH LITACDKLLE ARVERNDYVI ALGGGVIGDL 

       130        140        150        160        170        180 
SGFAAGIVRR GVRFVQVPTS LLSQVDSSVG GKTGINSRHG KNLIGVFHQP DLVLADTDVL 

       190        200        210        220        230        240 
NSLSEREFRA GYAEVAKYGL IDKPDFFAWL EANWKSVFTG GSARIEAIAA SCQAKADVVV 

       250        260        270        280        290        300 
ADERENGQRA LLNLGHTFGH ALEAATAYDS SRLVHGEGVS IGMVLAYEFS ARMNLASPDD 

       310        320        330        340        350        360 
ARRVERHLKE VGLPTRMSDI PGDLPPAETL MDAIAQDKKV KSGKLTFILT RGIGQSFVAD 

       370 
DVPASEVISF LREKHA

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		AM236080 Genomic DNA. Translation: CAK09839.1.
RefSeqYP_769923.1. NC_008380.1.

3D structure databases

ProteinModelPortalQ1MB46.
ModBaseSearch...

Protein-protein interaction databases

STRINGQ1MB46.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID4400749.
GenomeReviewsGene locus RL4352 in contig AM236080_GR.
KEGGrle:RL4352.
NMPDRfig|216596.1.peg.4487.
PATRIC23145559. VBIRhiLeg32091_5683.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0337.
HOGENOMHBG632303.
OMAVMALEMS.
PhylomeDBQ1MB46.
ProtClustDBPRK00002.

Enzyme and pathway databases

BioCycRLEG216596:RL4352-MONOMER.

Family and domain databases

HAMAPMF_00110. DHQ_synthase.
[Tree]
InterProIPR016037. DHQ_synth_AroB.
[Graphical view]
KOK01735.
PANTHERPTHR21090:SF1. DHQ_synth_AroB. 1 hit.
PIRSFPIRSF001455. DHQ_synth. 1 hit.
TIGRFAMsTIGR01357. AroB. 1 hit.
ProtoNetSearch...

Entry information

Entry nameAROB_RHIL3
AccessionPrimary (citable) accession number: Q1MB46
Entry history
Integrated into UniProtKB/Swiss-Prot: March 24, 2009
Last sequence update: May 30, 2006
Last modified: January 25, 2012
This is version 40 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·Documents