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Protein

Putative thiamine transporter SLC35F3

Gene

Slc35f3

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

May be a thiamine transporter.By similarity

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

Transport

Names & Taxonomyi

Protein namesi
Recommended name:
Putative thiamine transporter SLC35F3By similarity
Alternative name(s):
Solute carrier family 35 member F3
Gene namesi
Name:Slc35f3
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 8

Organism-specific databases

MGIiMGI:2444426. Slc35f3.

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei66 – 86HelicalSequence analysisAdd BLAST21
Transmembranei98 – 118HelicalSequence analysisAdd BLAST21
Transmembranei149 – 169HelicalSequence analysisAdd BLAST21
Transmembranei179 – 199HelicalSequence analysisAdd BLAST21
Transmembranei208 – 228HelicalSequence analysisAdd BLAST21
Transmembranei232 – 252HelicalSequence analysisAdd BLAST21
Transmembranei266 – 286HelicalSequence analysisAdd BLAST21
Transmembranei305 – 325HelicalSequence analysisAdd BLAST21
Transmembranei326 – 346HelicalSequence analysisAdd BLAST21
Transmembranei352 – 372HelicalSequence analysisAdd BLAST21

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003078801 – 421Putative thiamine transporter SLC35F3Add BLAST421

Proteomic databases

PaxDbiQ1LZI2.
PRIDEiQ1LZI2.

PTM databases

iPTMnetiQ1LZI2.
PhosphoSitePlusiQ1LZI2.

Expressioni

Gene expression databases

BgeeiENSMUSG00000057060.
CleanExiMM_SLC35F3.
GenevisibleiQ1LZI2. MM.

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000104390.

Structurei

3D structure databases

ProteinModelPortaliQ1LZI2.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the SLC35F solute transporter family.Curated

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiKOG4314. Eukaryota.
ENOG4110PN8. LUCA.
GeneTreeiENSGT00390000008727.
HOGENOMiHOG000060188.
HOVERGENiHBG108446.
InParanoidiQ1LZI2.
KOiK15288.
OMAiFGIAITY.
OrthoDBiEOG091G070X.
PhylomeDBiQ1LZI2.
TreeFamiTF313798.

Family and domain databases

InterProiIPR000620. EamA_dom.
IPR026505. Solute_c_fam_35_mem_F3/F4.
[Graphical view]
PANTHERiPTHR19346. PTHR19346. 1 hit.
PfamiPF00892. EamA. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q1LZI2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKKHSARVAP LSACNSPVLT LTKVEGEERP REPPGPAEAQ APAGTEAGGR
60 70 80 90 100
TSRHNWTCSQ ERLKKVFWGV AVVFCVCASW AGSTQLARLT FKTFDAPFTL
110 120 130 140 150
TWFATNWNFL FFPLYYAGHV CKSTEKQSMK QRYRECCRFF GDNGLTLKVF
160 170 180 190 200
FTKAAPFGVL WTLTNYLYLH AIKKINATDV SVLFCCNKSF VFLLSWIVLR
210 220 230 240 250
DRFMGVRIVA AILAIAGIVM MTYADGFHSH SVIGIALVVG SASMSALYKV
260 270 280 290 300
LFKLLLGSAK FGEAALFLSI LGVFNILFIT CIPVILYFTR VEYWNSFDDI
310 320 330 340 350
PWGNLCGFSI LLLTFNIVLN FGIAVTYPTL MSLGIVLSVP VNAVVDHYTS
360 370 380 390 400
QIVFNGVRVI AIIIIGLGFL LLLLPEEWDV WLIKLLTRLK VRKKEETAES
410 420
SGDLGTGPQS RSRRARPSFA R
Length:421
Mass (Da):46,924
Last modified:May 30, 2006 - v1
Checksum:i40259CC972850054
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti86 – 109LARLT…TNWNF → ARQADFQDLRRTVHPDVVCH QLEL in BAC32690 (PubMed:16141072).CuratedAdd BLAST24
Sequence conflicti153K → R in BAC32690 (PubMed:16141072).Curated1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK046359 mRNA. Translation: BAC32690.1.
BC115859 mRNA. Translation: AAI15860.1.
BC115965 mRNA. Translation: AAI15966.1.
CCDSiCCDS40520.1.
RefSeqiNP_780643.2. NM_175434.3.
UniGeneiMm.405238.
Mm.459322.

Genome annotation databases

EnsembliENSMUST00000108759; ENSMUSP00000104390; ENSMUSG00000057060.
GeneIDi210027.
KEGGimmu:210027.
UCSCiuc009nys.1. mouse.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK046359 mRNA. Translation: BAC32690.1.
BC115859 mRNA. Translation: AAI15860.1.
BC115965 mRNA. Translation: AAI15966.1.
CCDSiCCDS40520.1.
RefSeqiNP_780643.2. NM_175434.3.
UniGeneiMm.405238.
Mm.459322.

3D structure databases

ProteinModelPortaliQ1LZI2.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000104390.

PTM databases

iPTMnetiQ1LZI2.
PhosphoSitePlusiQ1LZI2.

Proteomic databases

PaxDbiQ1LZI2.
PRIDEiQ1LZI2.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000108759; ENSMUSP00000104390; ENSMUSG00000057060.
GeneIDi210027.
KEGGimmu:210027.
UCSCiuc009nys.1. mouse.

Organism-specific databases

CTDi148641.
MGIiMGI:2444426. Slc35f3.

Phylogenomic databases

eggNOGiKOG4314. Eukaryota.
ENOG4110PN8. LUCA.
GeneTreeiENSGT00390000008727.
HOGENOMiHOG000060188.
HOVERGENiHBG108446.
InParanoidiQ1LZI2.
KOiK15288.
OMAiFGIAITY.
OrthoDBiEOG091G070X.
PhylomeDBiQ1LZI2.
TreeFamiTF313798.

Miscellaneous databases

PROiQ1LZI2.
SOURCEiSearch...

Gene expression databases

BgeeiENSMUSG00000057060.
CleanExiMM_SLC35F3.
GenevisibleiQ1LZI2. MM.

Family and domain databases

InterProiIPR000620. EamA_dom.
IPR026505. Solute_c_fam_35_mem_F3/F4.
[Graphical view]
PANTHERiPTHR19346. PTHR19346. 1 hit.
PfamiPF00892. EamA. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiS35F3_MOUSE
AccessioniPrimary (citable) accession number: Q1LZI2
Secondary accession number(s): Q8BL51
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 23, 2007
Last sequence update: May 30, 2006
Last modified: November 2, 2016
This is version 64 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.