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Protein

ATP synthase mitochondrial F1 complex assembly factor 2

Gene

ATPAF2

Organism
Bos taurus (Bovine)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

May play a role in the assembly of the F1 component of the mitochondrial ATP synthase (ATPase).

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Chaperone

Names & Taxonomyi

Protein namesi
Recommended name:
ATP synthase mitochondrial F1 complex assembly factor 2
Gene namesi
Name:ATPAF2
OrganismiBos taurus (Bovine)
Taxonomic identifieri9913 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaCetartiodactylaRuminantiaPecoraBovidaeBovinaeBos
Proteomesi
  • UP000009136 Componenti: Chromosome 19

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Mitochondrion

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transit peptidei1 – 40MitochondrionSequence analysisAdd BLAST40
ChainiPRO_000026956241 – 289ATP synthase mitochondrial F1 complex assembly factor 2Add BLAST249

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei133N6-succinyllysineBy similarity1

Proteomic databases

PaxDbiQ1LZ96.
PRIDEiQ1LZ96.

Expressioni

Gene expression databases

BgeeiENSBTAG00000008801.

Interactioni

Subunit structurei

Interacts with ATP5A1.By similarity

Protein-protein interaction databases

STRINGi9913.ENSBTAP00000011594.

Structurei

3D structure databases

ProteinModelPortaliQ1LZ96.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the ATP12 family.Curated

Keywords - Domaini

Transit peptide

Phylogenomic databases

eggNOGiKOG3015. Eukaryota.
COG5387. LUCA.
GeneTreeiENSGT00390000009492.
HOGENOMiHOG000139577.
HOVERGENiHBG063751.
InParanoidiQ1LZ96.
KOiK07556.
OMAiHDVDYHD.
OrthoDBiEOG091G0GQO.
TreeFamiTF315138.

Family and domain databases

Gene3Di1.10.3580.10. 1 hit.
InterProiIPR011419. ATP12_ATP_synth-F1-assembly.
IPR023335. ATPase_assmbl_ATP12_dom.
[Graphical view]
PANTHERiPTHR21013. PTHR21013. 1 hit.
PfamiPF07542. ATP12. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q1LZ96-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MWRRCLRLRD VGRRLLNLPR SGLTASEGLG PKLPTPIRAY VPPAERKRFY
60 70 80 90 100
QNVSISQGEG GFEINLDHRK LRTPQGKLFT VPSEALAIAV ATEWDSQQDT
110 120 130 140 150
IKMYTMHLTT LCNTSLDNPT QRDKDQLIRA AVKFLDTDTV CYRVEEPETL
160 170 180 190 200
VELQRNEWDP VISWAEKRYG VEIGSSTSIT GPSIPARTRE VLVSHLASYN
210 220 230 240 250
MWALQGIEFV VTQLKSLVLT LGLTDLRLTV EQAVLLSRLE EEYQIQKWGN
260 270 280
IEWAHDYELQ ELRARTAAGT LFVHLCSEST AVKHKLLQG
Length:289
Mass (Da):32,860
Last modified:May 30, 2006 - v1
Checksum:i924B3D15D1A4167B
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC116131 mRNA. Translation: AAI16132.1.
RefSeqiNP_001069091.1. NM_001075623.1.
UniGeneiBt.59430.

Genome annotation databases

EnsembliENSBTAT00000011594; ENSBTAP00000011594; ENSBTAG00000008801.
GeneIDi513521.
KEGGibta:513521.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC116131 mRNA. Translation: AAI16132.1.
RefSeqiNP_001069091.1. NM_001075623.1.
UniGeneiBt.59430.

3D structure databases

ProteinModelPortaliQ1LZ96.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9913.ENSBTAP00000011594.

Proteomic databases

PaxDbiQ1LZ96.
PRIDEiQ1LZ96.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSBTAT00000011594; ENSBTAP00000011594; ENSBTAG00000008801.
GeneIDi513521.
KEGGibta:513521.

Organism-specific databases

CTDi91647.

Phylogenomic databases

eggNOGiKOG3015. Eukaryota.
COG5387. LUCA.
GeneTreeiENSGT00390000009492.
HOGENOMiHOG000139577.
HOVERGENiHBG063751.
InParanoidiQ1LZ96.
KOiK07556.
OMAiHDVDYHD.
OrthoDBiEOG091G0GQO.
TreeFamiTF315138.

Gene expression databases

BgeeiENSBTAG00000008801.

Family and domain databases

Gene3Di1.10.3580.10. 1 hit.
InterProiIPR011419. ATP12_ATP_synth-F1-assembly.
IPR023335. ATPase_assmbl_ATP12_dom.
[Graphical view]
PANTHERiPTHR21013. PTHR21013. 1 hit.
PfamiPF07542. ATP12. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiATPF2_BOVIN
AccessioniPrimary (citable) accession number: Q1LZ96
Entry historyi
Integrated into UniProtKB/Swiss-Prot: December 12, 2006
Last sequence update: May 30, 2006
Last modified: November 30, 2016
This is version 65 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.