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Protein

Zinc finger protein 397

Gene

ZNF397

Organism
Bos taurus (Bovine)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

DNA-dependent transcriptional repressor.By similarity

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Zinc fingeri285 – 30723C2H2-type 1PROSITE-ProRule annotationAdd
BLAST
Zinc fingeri313 – 33523C2H2-type 2PROSITE-ProRule annotationAdd
BLAST
Zinc fingeri341 – 36323C2H2-type 3PROSITE-ProRule annotationAdd
BLAST
Zinc fingeri369 – 39123C2H2-type 4PROSITE-ProRule annotationAdd
BLAST
Zinc fingeri397 – 41923C2H2-type 5PROSITE-ProRule annotationAdd
BLAST
Zinc fingeri425 – 44723C2H2-type 6PROSITE-ProRule annotationAdd
BLAST
Zinc fingeri453 – 47523C2H2-type 7PROSITE-ProRule annotationAdd
BLAST
Zinc fingeri481 – 50323C2H2-type 8PROSITE-ProRule annotationAdd
BLAST
Zinc fingeri509 – 53123C2H2-type 9PROSITE-ProRule annotationAdd
BLAST

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Repressor

Keywords - Biological processi

Transcription, Transcription regulation

Keywords - Ligandi

DNA-binding, Metal-binding, Zinc

Names & Taxonomyi

Protein namesi
Recommended name:
Zinc finger protein 397
Gene namesi
Name:ZNF397
OrganismiBos taurus (Bovine)
Taxonomic identifieri9913 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaCetartiodactylaRuminantiaPecoraBovidaeBovinaeBos
Proteomesi
  • UP000009136 Componenti: Chromosome 24

Subcellular locationi

  • Nucleus PROSITE-ProRule annotation

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 534534Zinc finger protein 397PRO_0000269561Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Cross-linki171 – 171Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)By similarity

Keywords - PTMi

Isopeptide bond, Ubl conjugation

Proteomic databases

PaxDbiQ1LZ87.
PRIDEiQ1LZ87.

Expressioni

Gene expression databases

ExpressionAtlasiQ1LZ87. baseline.

Interactioni

Protein-protein interaction databases

STRINGi9913.ENSBTAP00000056080.

Structurei

3D structure databases

ProteinModelPortaliQ1LZ87.
SMRiQ1LZ87. Positions 47-135, 282-532.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini50 – 13283SCAN boxPROSITE-ProRule annotationAdd
BLAST

Sequence similaritiesi

Contains 9 C2H2-type zinc fingers.PROSITE-ProRule annotation
Contains 1 SCAN box domain.PROSITE-ProRule annotation

Zinc finger

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Zinc fingeri285 – 30723C2H2-type 1PROSITE-ProRule annotationAdd
BLAST
Zinc fingeri313 – 33523C2H2-type 2PROSITE-ProRule annotationAdd
BLAST
Zinc fingeri341 – 36323C2H2-type 3PROSITE-ProRule annotationAdd
BLAST
Zinc fingeri369 – 39123C2H2-type 4PROSITE-ProRule annotationAdd
BLAST
Zinc fingeri397 – 41923C2H2-type 5PROSITE-ProRule annotationAdd
BLAST
Zinc fingeri425 – 44723C2H2-type 6PROSITE-ProRule annotationAdd
BLAST
Zinc fingeri453 – 47523C2H2-type 7PROSITE-ProRule annotationAdd
BLAST
Zinc fingeri481 – 50323C2H2-type 8PROSITE-ProRule annotationAdd
BLAST
Zinc fingeri509 – 53123C2H2-type 9PROSITE-ProRule annotationAdd
BLAST

Keywords - Domaini

Repeat, Zinc-finger

Phylogenomic databases

eggNOGiKOG1721. Eukaryota.
COG5048. LUCA.
GeneTreeiENSGT00840000129700.
HOGENOMiHOG000234619.
HOVERGENiHBG018163.
InParanoidiQ1LZ87.
KOiK09230.

Family and domain databases

Gene3Di3.30.160.60. 9 hits.
InterProiIPR008916. Retrov_capsid_C.
IPR003309. SCAN_dom.
IPR007087. Znf_C2H2.
IPR015880. Znf_C2H2-like.
IPR013087. Znf_C2H2/integrase_DNA-bd.
[Graphical view]
PfamiPF02023. SCAN. 1 hit.
PF00096. zf-C2H2. 6 hits.
[Graphical view]
SMARTiSM00431. SCAN. 1 hit.
SM00355. ZnF_C2H2. 9 hits.
[Graphical view]
SUPFAMiSSF47353. SSF47353. 1 hit.
PROSITEiPS50804. SCAN_BOX. 1 hit.
PS00028. ZINC_FINGER_C2H2_1. 9 hits.
PS50157. ZINC_FINGER_C2H2_2. 9 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q1LZ87-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAVESRAVST PVPQNSQEQE LILVKVEESR SWGQKLKQSG SARSCQELFR
60 70 80 90 100
QQFRKFCYQE TPGPREALGR LQELCYQWLR PELHTKEQIL ELLVLEQFLS
110 120 130 140 150
ILPEELQIWV QQHSPKNGEE AVTLLEDLER EFDDPGQQVP ATPQGPPMPW
160 170 180 190 200
KDLTCLGAAQ EFTHIQRQPL KKQLKPWEPC LPPKSGCENN ESAIKKDISG
210 220 230 240 250
EKSQRLSQEP SFGGFSEHKS SLEWQQGSAP GETLRRSPSQ RASFSPVIFT
260 270 280 290 300
HKLLANRDHP EPQRNLILST NSVTYQKVPT EERPYRCDIC GHSFKQHSSL
310 320 330 340 350
TQHQRIHTGE KPYKCNQCGK AFSLRSYLII HQRIHSGEKA YECSECGKAF
360 370 380 390 400
NQSSALIRHR KIHTGEKACK CNECGKAFSQ SSYLIIHQRI HTGEKPYECN
410 420 430 440 450
ECGKTFSQSS KLIRHQRIHT GERPYECNEC GKAFRQSSEL ITHQRIHSGE
460 470 480 490 500
KPYECNECGK AFSLSSNLIR HQRIHSGEEP YQCNECGKTF KRSSALVQHQ
510 520 530
RIHSGEEAYI CSECGKAFRH RSVLTRHQRV HTVK
Length:534
Mass (Da):61,277
Last modified:May 30, 2006 - v1
Checksum:i119647F1529CB8C8
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC116143 mRNA. Translation: AAI16144.1.
RefSeqiNP_001068730.1. NM_001075262.1.
XP_005224020.1. XM_005223963.3.
UniGeneiBt.28733.
Bt.91867.

Genome annotation databases

EnsembliENSBTAT00000013542; ENSBTAP00000013542; ENSBTAG00000010252.
GeneIDi506448.
KEGGibta:506448.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC116143 mRNA. Translation: AAI16144.1.
RefSeqiNP_001068730.1. NM_001075262.1.
XP_005224020.1. XM_005223963.3.
UniGeneiBt.28733.
Bt.91867.

3D structure databases

ProteinModelPortaliQ1LZ87.
SMRiQ1LZ87. Positions 47-135, 282-532.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9913.ENSBTAP00000056080.

Proteomic databases

PaxDbiQ1LZ87.
PRIDEiQ1LZ87.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSBTAT00000013542; ENSBTAP00000013542; ENSBTAG00000010252.
GeneIDi506448.
KEGGibta:506448.

Organism-specific databases

CTDi84307.

Phylogenomic databases

eggNOGiKOG1721. Eukaryota.
COG5048. LUCA.
GeneTreeiENSGT00840000129700.
HOGENOMiHOG000234619.
HOVERGENiHBG018163.
InParanoidiQ1LZ87.
KOiK09230.

Gene expression databases

ExpressionAtlasiQ1LZ87. baseline.

Family and domain databases

Gene3Di3.30.160.60. 9 hits.
InterProiIPR008916. Retrov_capsid_C.
IPR003309. SCAN_dom.
IPR007087. Znf_C2H2.
IPR015880. Znf_C2H2-like.
IPR013087. Znf_C2H2/integrase_DNA-bd.
[Graphical view]
PfamiPF02023. SCAN. 1 hit.
PF00096. zf-C2H2. 6 hits.
[Graphical view]
SMARTiSM00431. SCAN. 1 hit.
SM00355. ZnF_C2H2. 9 hits.
[Graphical view]
SUPFAMiSSF47353. SSF47353. 1 hit.
PROSITEiPS50804. SCAN_BOX. 1 hit.
PS00028. ZINC_FINGER_C2H2_1. 9 hits.
PS50157. ZINC_FINGER_C2H2_2. 9 hits.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. NIH - Mammalian Gene Collection (MGC) project
    Submitted (MAY-2006) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Strain: Hereford.
    Tissue: Hippocampus.

Entry informationi

Entry nameiZN397_BOVIN
AccessioniPrimary (citable) accession number: Q1LZ87
Entry historyi
Integrated into UniProtKB/Swiss-Prot: December 12, 2006
Last sequence update: May 30, 2006
Last modified: June 8, 2016
This is version 84 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.