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Q1LWP9

- Q1LWP9_DANRE

UniProt

Q1LWP9 - Q1LWP9_DANRE

Protein
Submitted name:

Neuraminidase 1

Gene

neu1

Organism
Danio rerio (Zebrafish) (Brachydanio rerio)
Status
Unreviewed - Annotation score: 1 out of 5- Experimental evidence at transcript leveli
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    • History
      Entry version 64 (01 Oct 2014)
      Sequence version 1 (30 May 2006)
      Previous versions | rss
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    Functioni

    GO - Molecular functioni

    1. exo-alpha-sialidase activity Source: InterPro

    Enzyme and pathway databases

    ReactomeiREACT_221391. Glycosphingolipid metabolism.
    REACT_221720. Sialic acid metabolism.

    Protein family/group databases

    CAZyiGH33. Glycoside Hydrolase Family 33.

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    Neuraminidase 1Imported
    Submitted name:
    Novel protein similar to vertebrate sialidase 1 (Lysosomal sialidase) (NEU1)Imported
    Submitted name:
    Uncharacterized proteinImported
    Gene namesi
    Name:neu1Imported
    Synonyms:si:ch211-222e23.1Imported
    ORF Names:CH211-222E23.1-001Imported
    OrganismiDanio rerio (Zebrafish) (Brachydanio rerio)Imported
    Taxonomic identifieri7955 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiActinopterygiiNeopterygiiTeleosteiOstariophysiCypriniformesCyprinidaeDanio
    ProteomesiUP000000437: Chromosome 19

    Organism-specific databases

    ZFINiZDB-GENE-060503-592. neu1.

    Interactioni

    Protein-protein interaction databases

    STRINGi7955.ENSDARP00000015727.

    Family & Domainsi

    Phylogenomic databases

    eggNOGiCOG4409.
    GeneTreeiENSGT00720000108878.
    HOGENOMiHOG000007651.
    HOVERGENiHBG057314.
    InParanoidiQ1LWP9.
    KOiK01186.
    OMAiGTEMFAP.
    OrthoDBiEOG779NXT.
    TreeFamiTF331063.

    Family and domain databases

    Gene3Di2.120.10.10. 1 hit.
    InterProiIPR026856. Sialidase_fam.
    IPR011040. Sialidases.
    [Graphical view]
    PANTHERiPTHR10628. PTHR10628. 1 hit.
    SUPFAMiSSF50939. SSF50939. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    Q1LWP9-1 [UniParc]FASTAAdd to Basket

    « Hide

    MDFIRQIGIL LGIAVLSSAR ADKTQIDPLI YEEQLLWVSG GAGQVNAYRI    50
    PLLTFTLRGS LLAFSEARKM SSSDIGAKFI ALRRSTDRGA TWSPTSFIVD 100
    DGSLADGLSL GSVVVDEETG AVIIIYSLCF HQYQCSPSST MMVQSLDDGF 150
    TWSVPRNLSI ELGVKSFAPG PGFGIQKRYP PSKGRLVVCG HGTIAGDGVF 200
    CILSDDHGRS WRYGAALKSI PYNQPKQDLD FNPDECQPVE LEDGSIVINV 250
    RNQNNYHCRC RIIVRSLDGG ESLPVEELVF DKTLIDPVVA AGALQKQGVM 300
    YFTNPSSTQH RVNLTLRWSF TDGKSWEKEA VQIWAGPSGY STMTSLKGGS 350
    AEDNKYIFVV YEKGHKDYWE TISFAKIHLY GGK 383
    Length:383
    Mass (Da):42,145
    Last modified:May 30, 2006 - v1
    Checksum:i188A60BA1612D610
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    FP085398 Genomic DNA. No translation available.
    BC133832 mRNA. Translation: AAI33833.1.
    BX537337 Genomic DNA. Translation: CAK04566.1.
    RefSeqiNP_001038374.1. NM_001044909.2.
    UniGeneiDr.79166.

    Genome annotation databases

    EnsembliENSDART00000002464; ENSDARP00000015727; ENSDARG00000008832.
    GeneIDi559850.
    KEGGidre:559850.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    FP085398 Genomic DNA. No translation available.
    BC133832 mRNA. Translation: AAI33833.1 .
    BX537337 Genomic DNA. Translation: CAK04566.1 .
    RefSeqi NP_001038374.1. NM_001044909.2.
    UniGenei Dr.79166.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 7955.ENSDARP00000015727.

    Protein family/group databases

    CAZyi GH33. Glycoside Hydrolase Family 33.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENSDART00000002464 ; ENSDARP00000015727 ; ENSDARG00000008832 .
    GeneIDi 559850.
    KEGGi dre:559850.

    Organism-specific databases

    CTDi 4758.
    ZFINi ZDB-GENE-060503-592. neu1.

    Phylogenomic databases

    eggNOGi COG4409.
    GeneTreei ENSGT00720000108878.
    HOGENOMi HOG000007651.
    HOVERGENi HBG057314.
    InParanoidi Q1LWP9.
    KOi K01186.
    OMAi GTEMFAP.
    OrthoDBi EOG779NXT.
    TreeFami TF331063.

    Enzyme and pathway databases

    Reactomei REACT_221391. Glycosphingolipid metabolism.
    REACT_221720. Sialic acid metabolism.

    Miscellaneous databases

    NextBioi 20883171.
    PROi Q1LWP9.

    Family and domain databases

    Gene3Di 2.120.10.10. 1 hit.
    InterProi IPR026856. Sialidase_fam.
    IPR011040. Sialidases.
    [Graphical view ]
    PANTHERi PTHR10628. PTHR10628. 1 hit.
    SUPFAMi SSF50939. SSF50939. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. NIH - Zebrafish Gene Collection (ZGC) project
      Submitted (MAR-2007) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
      Tissue: OvaryImported.
    2. Woodmansey R.
      Submitted (JAN-2009) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE.
    3. Ensembl
      Submitted (FEB-2012) to UniProtKB
      Cited for: IDENTIFICATION.
      Strain: TuebingenImported.
    4. "The zebrafish reference genome sequence and its relationship to the human genome."
      Howe K., Clark M.D., Torroja C.F., Torrance J., Berthelot C., Muffato M., Collins J.E., Humphray S., McLaren K., Matthews L., McLaren S., Sealy I., Caccamo M., Churcher C., Scott C., Barrett J.C., Koch R., Rauch G.J.
      , White S., Chow W., Kilian B., Quintais L.T., Guerra-Assuncao J.A., Zhou Y., Gu Y., Yen J., Vogel J.H., Eyre T., Redmond S., Banerjee R., Chi J., Fu B., Langley E., Maguire S.F., Laird G.K., Lloyd D., Kenyon E., Donaldson S., Sehra H., Almeida-King J., Loveland J., Trevanion S., Jones M., Quail M., Willey D., Hunt A., Burton J., Sims S., McLay K., Plumb B., Davis J., Clee C., Oliver K., Clark R., Riddle C., Eliott D., Threadgold G., Harden G., Ware D., Mortimer B., Kerry G., Heath P., Phillimore B., Tracey A., Corby N., Dunn M., Johnson C., Wood J., Clark S., Pelan S., Griffiths G., Smith M., Glithero R., Howden P., Barker N., Stevens C., Harley J., Holt K., Panagiotidis G., Lovell J., Beasley H., Henderson C., Gordon D., Auger K., Wright D., Collins J., Raisen C., Dyer L., Leung K., Robertson L., Ambridge K., Leongamornlert D., McGuire S., Gilderthorp R., Griffiths C., Manthravadi D., Nichol S., Barker G., Whitehead S., Kay M., Brown J., Murnane C., Gray E., Humphries M., Sycamore N., Barker D., Saunders D., Wallis J., Babbage A., Hammond S., Mashreghi-Mohammadi M., Barr L., Martin S., Wray P., Ellington A., Matthews N., Ellwood M., Woodmansey R., Clark G., Cooper J., Tromans A., Grafham D., Skuce C., Pandian R., Andrews R., Harrison E., Kimberley A., Garnett J., Fosker N., Hall R., Garner P., Kelly D., Bird C., Palmer S., Gehring I., Berger A., Dooley C.M., Ersan-Urun Z., Eser C., Geiger H., Geisler M., Karotki L., Kirn A., Konantz J., Konantz M., Oberlander M., Rudolph-Geiger S., Teucke M., Osoegawa K., Zhu B., Rapp A., Widaa S., Langford C., Yang F., Carter N.P., Harrow J., Ning Z., Herrero J., Searle S.M., Enright A., Geisler R., Plasterk R.H., Lee C., Westerfield M., de Jong P.J., Zon L.I., Postlethwait J.H., Nusslein-Volhard C., Hubbard T.J., Roest Crollius H., Rogers J., Stemple D.L.
      Nature 496:498-503(2013) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: TuebingenImported.

    Entry informationi

    Entry nameiQ1LWP9_DANRE
    AccessioniPrimary (citable) accession number: Q1LWP9
    Entry historyi
    Integrated into UniProtKB/TrEMBL: May 30, 2006
    Last sequence update: May 30, 2006
    Last modified: October 1, 2014
    This is version 64 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3