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Q1LWP9

- Q1LWP9_DANRE

UniProt

Q1LWP9 - Q1LWP9_DANRE

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Protein
Submitted name: Neuraminidase 1
Gene
neu1, si:ch211-222e23.1, CH211-222E23.1-001
Organism
Danio rerio (Zebrafish) (Brachydanio rerio)
Status
Unreviewed - Annotation score: 1 out of 5 - Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

  1. exo-alpha-sialidase activity Source: InterPro
Complete GO annotation...

Enzyme and pathway databases

ReactomeiREACT_221391. Glycosphingolipid metabolism.
REACT_221720. Sialic acid metabolism.

Protein family/group databases

CAZyiGH33. Glycoside Hydrolase Family 33.

Names & Taxonomyi

Protein namesi
Submitted name:
Neuraminidase 1Imported
Submitted name:
Novel protein similar to vertebrate sialidase 1 (Lysosomal sialidase) (NEU1)Imported
Submitted name:
Uncharacterized proteinImported
Gene namesi
Name:neu1Imported
Synonyms:si:ch211-222e23.1Imported
ORF Names:CH211-222E23.1-001Imported
OrganismiDanio rerio (Zebrafish) (Brachydanio rerio)
Taxonomic identifieri7955 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiActinopterygiiNeopterygiiTeleosteiOstariophysiCypriniformesCyprinidaeDanio
ProteomesiUP000000437: Chromosome 19

Organism-specific databases

ZFINiZDB-GENE-060503-592. neu1.

Interactioni

Protein-protein interaction databases

STRINGi7955.ENSDARP00000015727.

Family & Domainsi

Phylogenomic databases

eggNOGiCOG4409.
GeneTreeiENSGT00720000108878.
HOGENOMiHOG000007651.
HOVERGENiHBG057314.
InParanoidiQ1LWP9.
KOiK01186.
OMAiGTEMFAP.
OrthoDBiEOG779NXT.
TreeFamiTF331063.

Family and domain databases

Gene3Di2.120.10.10. 1 hit.
InterProiIPR026856. Sialidase_fam.
IPR011040. Sialidases.
[Graphical view]
PANTHERiPTHR10628. PTHR10628. 1 hit.
SUPFAMiSSF50939. SSF50939. 1 hit.

Sequencei

Sequence statusi: Complete.

Q1LWP9-1 [UniParc]FASTAAdd to Basket

« Hide

MDFIRQIGIL LGIAVLSSAR ADKTQIDPLI YEEQLLWVSG GAGQVNAYRI    50
PLLTFTLRGS LLAFSEARKM SSSDIGAKFI ALRRSTDRGA TWSPTSFIVD 100
DGSLADGLSL GSVVVDEETG AVIIIYSLCF HQYQCSPSST MMVQSLDDGF 150
TWSVPRNLSI ELGVKSFAPG PGFGIQKRYP PSKGRLVVCG HGTIAGDGVF 200
CILSDDHGRS WRYGAALKSI PYNQPKQDLD FNPDECQPVE LEDGSIVINV 250
RNQNNYHCRC RIIVRSLDGG ESLPVEELVF DKTLIDPVVA AGALQKQGVM 300
YFTNPSSTQH RVNLTLRWSF TDGKSWEKEA VQIWAGPSGY STMTSLKGGS 350
AEDNKYIFVV YEKGHKDYWE TISFAKIHLY GGK 383
Length:383
Mass (Da):42,145
Last modified:May 30, 2006 - v1
Checksum:i188A60BA1612D610
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
FP085398 Genomic DNA. No translation available.
BC133832 mRNA. Translation: AAI33833.1.
BX537337 Genomic DNA. Translation: CAK04566.1.
RefSeqiNP_001038374.1. NM_001044909.2.
UniGeneiDr.79166.

Genome annotation databases

EnsembliENSDART00000002464; ENSDARP00000015727; ENSDARG00000008832.
GeneIDi559850.
KEGGidre:559850.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
FP085398 Genomic DNA. No translation available.
BC133832 mRNA. Translation: AAI33833.1 .
BX537337 Genomic DNA. Translation: CAK04566.1 .
RefSeqi NP_001038374.1. NM_001044909.2.
UniGenei Dr.79166.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 7955.ENSDARP00000015727.

Protein family/group databases

CAZyi GH33. Glycoside Hydrolase Family 33.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENSDART00000002464 ; ENSDARP00000015727 ; ENSDARG00000008832 .
GeneIDi 559850.
KEGGi dre:559850.

Organism-specific databases

CTDi 4758.
ZFINi ZDB-GENE-060503-592. neu1.

Phylogenomic databases

eggNOGi COG4409.
GeneTreei ENSGT00720000108878.
HOGENOMi HOG000007651.
HOVERGENi HBG057314.
InParanoidi Q1LWP9.
KOi K01186.
OMAi GTEMFAP.
OrthoDBi EOG779NXT.
TreeFami TF331063.

Enzyme and pathway databases

Reactomei REACT_221391. Glycosphingolipid metabolism.
REACT_221720. Sialic acid metabolism.

Miscellaneous databases

NextBioi 20883171.
PROi Q1LWP9.

Family and domain databases

Gene3Di 2.120.10.10. 1 hit.
InterProi IPR026856. Sialidase_fam.
IPR011040. Sialidases.
[Graphical view ]
PANTHERi PTHR10628. PTHR10628. 1 hit.
SUPFAMi SSF50939. SSF50939. 1 hit.
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. NIH - Zebrafish Gene Collection (ZGC) project
    Submitted (MAR-2007) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Tissue: OvaryImported.
  2. Woodmansey R.
    Submitted (JAN-2009) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
  3. Ensembl
    Submitted (FEB-2012) to UniProtKB
    Cited for: IDENTIFICATION.
    Strain: TuebingenImported.
  4. "The zebrafish reference genome sequence and its relationship to the human genome."
    Howe K., Clark M.D., Torroja C.F., Torrance J., Berthelot C., Muffato M., Collins J.E., Humphray S., McLaren K., Matthews L., McLaren S., Sealy I., Caccamo M., Churcher C., Scott C., Barrett J.C., Koch R., Rauch G.J.
    , White S., Chow W., Kilian B., Quintais L.T., Guerra-Assuncao J.A., Zhou Y., Gu Y., Yen J., Vogel J.H., Eyre T., Redmond S., Banerjee R., Chi J., Fu B., Langley E., Maguire S.F., Laird G.K., Lloyd D., Kenyon E., Donaldson S., Sehra H., Almeida-King J., Loveland J., Trevanion S., Jones M., Quail M., Willey D., Hunt A., Burton J., Sims S., McLay K., Plumb B., Davis J., Clee C., Oliver K., Clark R., Riddle C., Eliott D., Threadgold G., Harden G., Ware D., Mortimer B., Kerry G., Heath P., Phillimore B., Tracey A., Corby N., Dunn M., Johnson C., Wood J., Clark S., Pelan S., Griffiths G., Smith M., Glithero R., Howden P., Barker N., Stevens C., Harley J., Holt K., Panagiotidis G., Lovell J., Beasley H., Henderson C., Gordon D., Auger K., Wright D., Collins J., Raisen C., Dyer L., Leung K., Robertson L., Ambridge K., Leongamornlert D., McGuire S., Gilderthorp R., Griffiths C., Manthravadi D., Nichol S., Barker G., Whitehead S., Kay M., Brown J., Murnane C., Gray E., Humphries M., Sycamore N., Barker D., Saunders D., Wallis J., Babbage A., Hammond S., Mashreghi-Mohammadi M., Barr L., Martin S., Wray P., Ellington A., Matthews N., Ellwood M., Woodmansey R., Clark G., Cooper J., Tromans A., Grafham D., Skuce C., Pandian R., Andrews R., Harrison E., Kimberley A., Garnett J., Fosker N., Hall R., Garner P., Kelly D., Bird C., Palmer S., Gehring I., Berger A., Dooley C.M., Ersan-Urun Z., Eser C., Geiger H., Geisler M., Karotki L., Kirn A., Konantz J., Konantz M., Oberlander M., Rudolph-Geiger S., Teucke M., Osoegawa K., Zhu B., Rapp A., Widaa S., Langford C., Yang F., Carter N.P., Harrow J., Ning Z., Herrero J., Searle S.M., Enright A., Geisler R., Plasterk R.H., Lee C., Westerfield M., de Jong P.J., Zon L.I., Postlethwait J.H., Nusslein-Volhard C., Hubbard T.J., Roest Crollius H., Rogers J., Stemple D.L.
    Nature 496:498-503(2013) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: TuebingenImported.

Entry informationi

Entry nameiQ1LWP9_DANRE
AccessioniPrimary (citable) accession number: Q1LWP9
Entry historyi
Integrated into UniProtKB/TrEMBL: May 30, 2006
Last sequence update: May 30, 2006
Last modified: September 3, 2014
This is version 63 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

External Data

Dasty 3

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