Q1LV36 (Q1LV36_DANRE) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Cytochrome P450, family 19, subfamily A, polypeptide 1a Ensembl ENSDARP00000111604 EMBL CAK04222.1

Gene names

Name:	cyp19a1a EMBL AAI63004.1 ZFIN ZDB-GENE-990415-43 Ensembl ENSDARP00000111604
ORF Names:	CH211-165A16.1-001 EMBL CAK04222.1

Organism

Danio rerio (Zebrafish) (Brachydanio rerio) EMBL CAK04222.1

Taxonomic identifier

7955 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Actinopterygii › Neopterygii › Teleostei › Ostariophysi › Cypriniformes › Cyprinidae › Danio

Protein attributes

Sequence length	517 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

General annotation (Comments)

Sequence similarities

Belongs to the cytochrome P450 family. RuleBase RU000461

Ontologies

Keywords
Ligand	Heme RuleBase RU000461 Iron Metal-binding
Molecular function	Monooxygenase RuleBase RU003700 Oxidoreductase
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological process	response to estradiol stimulus Inferred from direct assay. Source: ZFIN response to xenobiotic stimulus Inferred from direct assay. Source: ZFIN
Molecular function	electron carrier activity Inferred from electronic annotation. Source: InterPro heme binding Inferred from electronic annotation. Source: InterPro monooxygenase activity Inferred from electronic annotation. Source: UniProtKB-KW oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q1LV36 [UniParc]. Last modified May 30, 2006. Version 1. Checksum: F4AAFA9BC93357AB	FASTA	517	58,279
	10 20 30 40 50 60 MAGDLLQPCG MKPVRLGEAV VDLLIQRAHN GTERAQDNAC GATATILLLL LCLLLAIRHH 70 80 90 100 110 120 RPHKSHIPGP SFFFGLGPVV SYCRFIWSGI GTASNYYNSK YGDIVRVWIN GEETLILSRS 130 140 150 160 170 180 SAVYHVLRKS LYTSRFGSKL GLQCIGMHEQ GIIFNSNVAL WKKVRAFYAK ALTGPGLQRT 190 200 210 220 230 240 MEICTTSTNS HLDDLSQLTD AQGQLDILNL LRCIVVDVSN RLFLGVPLNE HDLLQKIHKY 250 260 270 280 290 300 FDTWQTVLIK PDVYFRLDWL HKKHKRDAQE LQDAITALIE QKKVQLAHAE KLDHLDFTAE 310 320 330 340 350 360 LIFAQSHGEL SAENVRQCVL EMVIAAPDTL SISLFFMLLL LKQNPDVELK ILQEMDSVLA 370 380 390 400 410 420 GQSLQHSHLS KLQILESFIN ESLRFHPVVD FTMRRALDDD VIEGYNVKKG TNIILNVGRM 430 440 450 460 470 480 HRSEFFSKPN QFSLDNFHKN VPSRFFQPFG SGPRSCVGKH IAMVMMKSIL VALLSRFSVC 490 500 510 PMKACTVENI PQTNNLSQQP VEEPSSLSVQ LILRNTL

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	NIH - Zebrafish Gene Collection (ZGC) project Submitted (APR-2008) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. Tissue: Pooled EMBL AAI63004.1.
[2]	Wood J. Submitted (JAN-2009) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE.
[3]	"The genomic sequence of Danio rerio." The Danio rerio Sequencing Project at the Sanger Institute Submitted (JUL-2010) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Tuebingen Ensembl ENSDARP00000111604.
[4]	Ensembl Submitted (JUL-2011) to UniProtKB Cited for: IDENTIFICATION. Strain: Tuebingen Ensembl ENSDARP00000111604.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	BC163004 mRNA. Translation: AAI63004.1. BC163008 mRNA. Translation: AAI63008.1. BX908722 Genomic DNA. Translation: CAK04222.1.
IPI	IPI00482226.
UniGene	Dr.75765.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	Q1LV36.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
Ensembl	ENSDART00000129828; ENSDARP00000111604; ENSDARG00000041348.
Organism-specific databases
ZFIN	ZDB-GENE-990415-43. cyp19a1a.
Phylogenomic databases
HOGENOM	HBG713559.
HOVERGEN	HBG050750.
InParanoid	Q1LV36.
OMA	DTWQTVL.
PhylomeDB	Q1LV36.
Gene expression databases
ArrayExpress	Q1LV36.
Bgee	Q1LV36.
Family and domain databases
InterPro	IPR001128. Cyt_P450. IPR017972. Cyt_P450_CS. IPR002401. Cyt_P450_E_grp-I. [Graphical view]
Gene3D	G3DSA:1.10.630.10. Cyt_P450. 1 hit.
Pfam	PF00067. p450. 1 hit. [Graphical view]
PRINTS	PR00463. EP450I. PR00385. P450.
SUPFAM	SSF48264. Cytochrome_P450. 1 hit.
PROSITE	PS00086. CYTOCHROME_P450. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

Q1LV36_DANRE

Accession

Primary (citable) accession number: Q1LV36

Entry history

Integrated into UniProtKB/TrEMBL:	May 30, 2006
Last sequence update:	May 30, 2006
Last modified:	January 25, 2012
This is version 43 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)