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Protein
Submitted name:

Uncharacterized protein

Gene

kat2b

Organism
Danio rerio (Zebrafish) (Brachydanio rerio)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Protein predictedi

Functioni

GO - Molecular functioni

  1. histone acetyltransferase activity Source: InterPro

GO - Biological processi

  1. regulation of transcription, DNA-templated Source: InterPro
Complete GO annotation...

Enzyme and pathway databases

ReactomeiREACT_310649. HATs acetylate histones.
REACT_314195. Constitutive Signaling by NOTCH1 PEST Domain Mutants.
REACT_314865. RNA Polymerase I Transcription Initiation.
REACT_317651. YAP1- and WWTR1 (TAZ)-stimulated gene expression.
REACT_318895. Notch-HLH transcription pathway.
REACT_319829. Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants.
REACT_322134. NOTCH1 Intracellular Domain Regulates Transcription.

Names & Taxonomyi

Protein namesi
Submitted name:
Uncharacterized proteinImported
Gene namesi
Name:kat2bImported
OrganismiDanio rerio (Zebrafish) (Brachydanio rerio)Imported
Taxonomic identifieri7955 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiActinopterygiiNeopterygiiTeleosteiOstariophysiCypriniformesCyprinidaeDanio
ProteomesiUP000000437 Componenti: Chromosome 19

Organism-specific databases

ZFINiZDB-GENE-060503-207. kat2b.

Subcellular locationi

GO - Cellular componenti

  1. nucleus Source: InterPro
Complete GO annotation...

Expressioni

Gene expression databases

BgeeiQ1LUC3.

Interactioni

Protein-protein interaction databases

STRINGi7955.ENSDARP00000085190.

Structurei

3D structure databases

ProteinModelPortaliQ1LUC3.
SMRiQ1LUC3. Positions 459-618, 683-796.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Keywords - Domaini

BromodomainSAAS annotation

Phylogenomic databases

eggNOGiCOG5076.
GeneTreeiENSGT00760000119099.
HOGENOMiHOG000007151.
HOVERGENiHBG051710.
InParanoidiQ1LUC3.
KOiK06062.
OMAiKIMMWLV.
OrthoDBiEOG7ZKS9B.
PhylomeDBiQ1LUC3.
TreeFamiTF105399.

Family and domain databases

Gene3Di1.20.920.10. 1 hit.
3.40.630.30. 1 hit.
InterProiIPR016181. Acyl_CoA_acyltransferase.
IPR001487. Bromodomain.
IPR018359. Bromodomain_CS.
IPR000182. GNAT_dom.
IPR016376. Hist_acetylase_PCAF.
IPR009464. PCAF_N.
[Graphical view]
PfamiPF13508. Acetyltransf_7. 1 hit.
PF00439. Bromodomain. 1 hit.
PF06466. PCAF_N. 1 hit.
[Graphical view]
PIRSFiPIRSF003048. Histone_acetylase_PCAF. 1 hit.
PRINTSiPR00503. BROMODOMAIN.
SMARTiSM00297. BROMO. 1 hit.
[Graphical view]
SUPFAMiSSF47370. SSF47370. 1 hit.
SSF55729. SSF55729. 1 hit.
PROSITEiPS00633. BROMODOMAIN_1. 1 hit.
PS50014. BROMODOMAIN_2. 1 hit.
PS51186. GNAT. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q1LUC3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSESTGIPQG SPAVGAAGSA PAAPGVGGTE CSGAAVGSAR IAVKKAQLRS
60 70 80 90 100
SPRPKKLEKL GVYSSCKAEG ACKCNGWKSQ NPPPTPPPPT PPRAEQPTAV
110 120 130 140 150
SLMEPCRSCS HALGDHVTHL ENVSEEEMNR LLGIVLDVEY LYTCVHKEED
160 170 180 190 200
PDTKQVYFSL FKLLRKCILQ MGRPVVEALE SPPFEKPSIE QGVNNFVQYK
210 220 230 240 250
FSHLPSKERQ TIVELAKMFL NQINYWQLET PSQKRQRAPD DDVAGYKVNY
260 270 280 290 300
TRWLCYCNVP QFCDSLPRYE ATQIFGRIFL RSVFTIMRKQ LLEQARQEKD
310 320 330 340 350
KLPPEKRTLI LTHFPKFLSM LEEEVYSHNS PIWSENFMIG LSGGQIPTVV
360 370 380 390 400
SAPPVNRSLY YSSSPAPVEL AGGGSVSPAR KTASVLEPNP GGEKRKPAEP
410 420 430 440 450
LSHEDSKRPR VVGDIPMELI NEVMSTITDP TAMLGPETSL LSAHSARDEA
460 470 480 490 500
ARLEERRGVI EFHVIGNSLN QKPNKKILMW LVGLQNVFSH QLPRMPKEYI
510 520 530 540 550
TRLVFDPKHK TLSLIKDGRV IGGICFRMFP TQGFTEIVFC AVTSNEQVKG
560 570 580 590 600
YGTHLMNHLK EYHIKHEILN FLTYADEYAI GYFKKQGFSK DIKVPKSKYV
610 620 630 640 650
GYIKDYEGAT LMGCELNPCI PYTEFSVIIK KQKEIIKKLI ERKQAQIRKV
660 670 680 690 700
YPGLSCFKEG VRQIAIESIP GIRETGWKPL GKSKELKDPD QLYSTLKNIL
710 720 730 740 750
TQVKSHPNAW PFMEPVKKNE APGYYQVIRF PMDLKTMSER LKSRYYTTRK
760 770 780 790
LFMADMQRIF TNCREYNPPE SEYYKCANLL EKFFYTKIKE AGLIDK
Length:796
Mass (Da):90,026
Last modified:May 30, 2006 - v1
Checksum:iB1B321F4A513B9E5
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX950869 Genomic DNA. No translation available.
BX957344 Genomic DNA. No translation available.
RefSeqiNP_001038499.1. NM_001045034.1.
UniGeneiDr.97337.

Genome annotation databases

EnsembliENSDART00000090757; ENSDARP00000085190; ENSDARG00000062634.
GeneIDi563942.
KEGGidre:563942.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX950869 Genomic DNA. No translation available.
BX957344 Genomic DNA. No translation available.
RefSeqiNP_001038499.1. NM_001045034.1.
UniGeneiDr.97337.

3D structure databases

ProteinModelPortaliQ1LUC3.
SMRiQ1LUC3. Positions 459-618, 683-796.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi7955.ENSDARP00000085190.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSDART00000090757; ENSDARP00000085190; ENSDARG00000062634.
GeneIDi563942.
KEGGidre:563942.

Organism-specific databases

CTDi8850.
ZFINiZDB-GENE-060503-207. kat2b.

Phylogenomic databases

eggNOGiCOG5076.
GeneTreeiENSGT00760000119099.
HOGENOMiHOG000007151.
HOVERGENiHBG051710.
InParanoidiQ1LUC3.
KOiK06062.
OMAiKIMMWLV.
OrthoDBiEOG7ZKS9B.
PhylomeDBiQ1LUC3.
TreeFamiTF105399.

Enzyme and pathway databases

ReactomeiREACT_310649. HATs acetylate histones.
REACT_314195. Constitutive Signaling by NOTCH1 PEST Domain Mutants.
REACT_314865. RNA Polymerase I Transcription Initiation.
REACT_317651. YAP1- and WWTR1 (TAZ)-stimulated gene expression.
REACT_318895. Notch-HLH transcription pathway.
REACT_319829. Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants.
REACT_322134. NOTCH1 Intracellular Domain Regulates Transcription.

Miscellaneous databases

NextBioi20885147.
PROiQ1LUC3.

Gene expression databases

BgeeiQ1LUC3.

Family and domain databases

Gene3Di1.20.920.10. 1 hit.
3.40.630.30. 1 hit.
InterProiIPR016181. Acyl_CoA_acyltransferase.
IPR001487. Bromodomain.
IPR018359. Bromodomain_CS.
IPR000182. GNAT_dom.
IPR016376. Hist_acetylase_PCAF.
IPR009464. PCAF_N.
[Graphical view]
PfamiPF13508. Acetyltransf_7. 1 hit.
PF00439. Bromodomain. 1 hit.
PF06466. PCAF_N. 1 hit.
[Graphical view]
PIRSFiPIRSF003048. Histone_acetylase_PCAF. 1 hit.
PRINTSiPR00503. BROMODOMAIN.
SMARTiSM00297. BROMO. 1 hit.
[Graphical view]
SUPFAMiSSF47370. SSF47370. 1 hit.
SSF55729. SSF55729. 1 hit.
PROSITEiPS00633. BROMODOMAIN_1. 1 hit.
PS50014. BROMODOMAIN_2. 1 hit.
PS51186. GNAT. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "The zebrafish reference genome sequence and its relationship to the human genome."
    Howe K., Clark M.D., Torroja C.F., Torrance J., Berthelot C., Muffato M., Collins J.E., Humphray S., McLaren K., Matthews L., McLaren S., Sealy I., Caccamo M., Churcher C., Scott C., Barrett J.C., Koch R., Rauch G.J.
    , White S., Chow W., Kilian B., Quintais L.T., Guerra-Assuncao J.A., Zhou Y., Gu Y., Yen J., Vogel J.H., Eyre T., Redmond S., Banerjee R., Chi J., Fu B., Langley E., Maguire S.F., Laird G.K., Lloyd D., Kenyon E., Donaldson S., Sehra H., Almeida-King J., Loveland J., Trevanion S., Jones M., Quail M., Willey D., Hunt A., Burton J., Sims S., McLay K., Plumb B., Davis J., Clee C., Oliver K., Clark R., Riddle C., Eliott D., Threadgold G., Harden G., Ware D., Mortimer B., Kerry G., Heath P., Phillimore B., Tracey A., Corby N., Dunn M., Johnson C., Wood J., Clark S., Pelan S., Griffiths G., Smith M., Glithero R., Howden P., Barker N., Stevens C., Harley J., Holt K., Panagiotidis G., Lovell J., Beasley H., Henderson C., Gordon D., Auger K., Wright D., Collins J., Raisen C., Dyer L., Leung K., Robertson L., Ambridge K., Leongamornlert D., McGuire S., Gilderthorp R., Griffiths C., Manthravadi D., Nichol S., Barker G., Whitehead S., Kay M., Brown J., Murnane C., Gray E., Humphries M., Sycamore N., Barker D., Saunders D., Wallis J., Babbage A., Hammond S., Mashreghi-Mohammadi M., Barr L., Martin S., Wray P., Ellington A., Matthews N., Ellwood M., Woodmansey R., Clark G., Cooper J., Tromans A., Grafham D., Skuce C., Pandian R., Andrews R., Harrison E., Kimberley A., Garnett J., Fosker N., Hall R., Garner P., Kelly D., Bird C., Palmer S., Gehring I., Berger A., Dooley C.M., Ersan-Urun Z., Eser C., Geiger H., Geisler M., Karotki L., Kirn A., Konantz J., Konantz M., Oberlander M., Rudolph-Geiger S., Teucke M., Osoegawa K., Zhu B., Rapp A., Widaa S., Langford C., Yang F., Carter N.P., Harrow J., Ning Z., Herrero J., Searle S.M., Enright A., Geisler R., Plasterk R.H., Lee C., Westerfield M., de Jong P.J., Zon L.I., Postlethwait J.H., Nusslein-Volhard C., Hubbard T.J., Roest Crollius H., Rogers J., Stemple D.L.
    Nature 496:498-503(2013) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: TuebingenImported.
  2. Ensembl
    Submitted (AUG-2013) to UniProtKB
    Cited for: IDENTIFICATION.
    Strain: TuebingenImported.

Entry informationi

Entry nameiQ1LUC3_DANRE
AccessioniPrimary (citable) accession number: Q1LUC3
Entry historyi
Integrated into UniProtKB/TrEMBL: May 30, 2006
Last sequence update: May 30, 2006
Last modified: April 1, 2015
This is version 71 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.