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Q1LUC3

- Q1LUC3_DANRE

UniProt

Q1LUC3 - Q1LUC3_DANRE

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Protein
Submitted name:

Uncharacterized protein

Gene

kat2b

Organism
Danio rerio (Zebrafish) (Brachydanio rerio)
Status
Unreviewed - Annotation score: 1 out of 5- Protein predictedi

Functioni

GO - Molecular functioni

  1. histone acetyltransferase activity Source: InterPro

GO - Biological processi

  1. regulation of transcription, DNA-templated Source: InterPro
Complete GO annotation...

Enzyme and pathway databases

ReactomeiREACT_216459. NOTCH1 Intracellular Domain Regulates Transcription.
REACT_221166. YAP1- and WWTR1 (TAZ)-stimulated gene expression.
REACT_223183. Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants.
REACT_227183. Constitutive Signaling by NOTCH1 PEST Domain Mutants.

Names & Taxonomyi

Protein namesi
Submitted name:
Uncharacterized proteinImported
Gene namesi
Name:kat2bImported
OrganismiDanio rerio (Zebrafish) (Brachydanio rerio)Imported
Taxonomic identifieri7955 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiActinopterygiiNeopterygiiTeleosteiOstariophysiCypriniformesCyprinidaeDanio
ProteomesiUP000000437: Chromosome 19

Organism-specific databases

ZFINiZDB-GENE-060503-207. kat2b.

Subcellular locationi

GO - Cellular componenti

  1. nucleus Source: InterPro
Complete GO annotation...

Interactioni

Protein-protein interaction databases

STRINGi7955.ENSDARP00000085190.

Structurei

3D structure databases

ProteinModelPortaliQ1LUC3.
SMRiQ1LUC3. Positions 459-618, 683-796.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Keywords - Domaini

BromodomainSAAS annotation

Phylogenomic databases

eggNOGiCOG5076.
GeneTreeiENSGT00760000119099.
HOGENOMiHOG000007151.
HOVERGENiHBG051710.
InParanoidiQ1LUC3.
KOiK06062.
OMAiKIMMWLV.
OrthoDBiEOG7ZKS9B.
PhylomeDBiQ1LUC3.
TreeFamiTF105399.

Family and domain databases

Gene3Di1.20.920.10. 1 hit.
3.40.630.30. 1 hit.
InterProiIPR016181. Acyl_CoA_acyltransferase.
IPR001487. Bromodomain.
IPR018359. Bromodomain_CS.
IPR000182. GNAT_dom.
IPR016376. Hist_acetylase_PCAF.
IPR009464. PCAF_N.
[Graphical view]
PfamiPF13508. Acetyltransf_7. 1 hit.
PF00439. Bromodomain. 1 hit.
PF06466. PCAF_N. 1 hit.
[Graphical view]
PIRSFiPIRSF003048. Histone_acetylase_PCAF. 1 hit.
PRINTSiPR00503. BROMODOMAIN.
SMARTiSM00297. BROMO. 1 hit.
[Graphical view]
SUPFAMiSSF47370. SSF47370. 1 hit.
SSF55729. SSF55729. 1 hit.
PROSITEiPS00633. BROMODOMAIN_1. 1 hit.
PS50014. BROMODOMAIN_2. 1 hit.
PS51186. GNAT. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q1LUC3 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MSESTGIPQG SPAVGAAGSA PAAPGVGGTE CSGAAVGSAR IAVKKAQLRS
60 70 80 90 100
SPRPKKLEKL GVYSSCKAEG ACKCNGWKSQ NPPPTPPPPT PPRAEQPTAV
110 120 130 140 150
SLMEPCRSCS HALGDHVTHL ENVSEEEMNR LLGIVLDVEY LYTCVHKEED
160 170 180 190 200
PDTKQVYFSL FKLLRKCILQ MGRPVVEALE SPPFEKPSIE QGVNNFVQYK
210 220 230 240 250
FSHLPSKERQ TIVELAKMFL NQINYWQLET PSQKRQRAPD DDVAGYKVNY
260 270 280 290 300
TRWLCYCNVP QFCDSLPRYE ATQIFGRIFL RSVFTIMRKQ LLEQARQEKD
310 320 330 340 350
KLPPEKRTLI LTHFPKFLSM LEEEVYSHNS PIWSENFMIG LSGGQIPTVV
360 370 380 390 400
SAPPVNRSLY YSSSPAPVEL AGGGSVSPAR KTASVLEPNP GGEKRKPAEP
410 420 430 440 450
LSHEDSKRPR VVGDIPMELI NEVMSTITDP TAMLGPETSL LSAHSARDEA
460 470 480 490 500
ARLEERRGVI EFHVIGNSLN QKPNKKILMW LVGLQNVFSH QLPRMPKEYI
510 520 530 540 550
TRLVFDPKHK TLSLIKDGRV IGGICFRMFP TQGFTEIVFC AVTSNEQVKG
560 570 580 590 600
YGTHLMNHLK EYHIKHEILN FLTYADEYAI GYFKKQGFSK DIKVPKSKYV
610 620 630 640 650
GYIKDYEGAT LMGCELNPCI PYTEFSVIIK KQKEIIKKLI ERKQAQIRKV
660 670 680 690 700
YPGLSCFKEG VRQIAIESIP GIRETGWKPL GKSKELKDPD QLYSTLKNIL
710 720 730 740 750
TQVKSHPNAW PFMEPVKKNE APGYYQVIRF PMDLKTMSER LKSRYYTTRK
760 770 780 790
LFMADMQRIF TNCREYNPPE SEYYKCANLL EKFFYTKIKE AGLIDK
Length:796
Mass (Da):90,026
Last modified:May 30, 2006 - v1
Checksum:iB1B321F4A513B9E5
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
BX950869 Genomic DNA. No translation available.
BX957344 Genomic DNA. No translation available.
RefSeqiNP_001038499.1. NM_001045034.1.
UniGeneiDr.97337.

Genome annotation databases

EnsembliENSDART00000090757; ENSDARP00000085190; ENSDARG00000062634.
GeneIDi563942.
KEGGidre:563942.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
BX950869 Genomic DNA. No translation available.
BX957344 Genomic DNA. No translation available.
RefSeqi NP_001038499.1. NM_001045034.1.
UniGenei Dr.97337.

3D structure databases

ProteinModelPortali Q1LUC3.
SMRi Q1LUC3. Positions 459-618, 683-796.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 7955.ENSDARP00000085190.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENSDART00000090757 ; ENSDARP00000085190 ; ENSDARG00000062634 .
GeneIDi 563942.
KEGGi dre:563942.

Organism-specific databases

CTDi 8850.
ZFINi ZDB-GENE-060503-207. kat2b.

Phylogenomic databases

eggNOGi COG5076.
GeneTreei ENSGT00760000119099.
HOGENOMi HOG000007151.
HOVERGENi HBG051710.
InParanoidi Q1LUC3.
KOi K06062.
OMAi KIMMWLV.
OrthoDBi EOG7ZKS9B.
PhylomeDBi Q1LUC3.
TreeFami TF105399.

Enzyme and pathway databases

Reactomei REACT_216459. NOTCH1 Intracellular Domain Regulates Transcription.
REACT_221166. YAP1- and WWTR1 (TAZ)-stimulated gene expression.
REACT_223183. Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants.
REACT_227183. Constitutive Signaling by NOTCH1 PEST Domain Mutants.

Miscellaneous databases

NextBioi 20885147.
PROi Q1LUC3.

Family and domain databases

Gene3Di 1.20.920.10. 1 hit.
3.40.630.30. 1 hit.
InterProi IPR016181. Acyl_CoA_acyltransferase.
IPR001487. Bromodomain.
IPR018359. Bromodomain_CS.
IPR000182. GNAT_dom.
IPR016376. Hist_acetylase_PCAF.
IPR009464. PCAF_N.
[Graphical view ]
Pfami PF13508. Acetyltransf_7. 1 hit.
PF00439. Bromodomain. 1 hit.
PF06466. PCAF_N. 1 hit.
[Graphical view ]
PIRSFi PIRSF003048. Histone_acetylase_PCAF. 1 hit.
PRINTSi PR00503. BROMODOMAIN.
SMARTi SM00297. BROMO. 1 hit.
[Graphical view ]
SUPFAMi SSF47370. SSF47370. 1 hit.
SSF55729. SSF55729. 1 hit.
PROSITEi PS00633. BROMODOMAIN_1. 1 hit.
PS50014. BROMODOMAIN_2. 1 hit.
PS51186. GNAT. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "The zebrafish reference genome sequence and its relationship to the human genome."
    Howe K., Clark M.D., Torroja C.F., Torrance J., Berthelot C., Muffato M., Collins J.E., Humphray S., McLaren K., Matthews L., McLaren S., Sealy I., Caccamo M., Churcher C., Scott C., Barrett J.C., Koch R., Rauch G.J.
    , White S., Chow W., Kilian B., Quintais L.T., Guerra-Assuncao J.A., Zhou Y., Gu Y., Yen J., Vogel J.H., Eyre T., Redmond S., Banerjee R., Chi J., Fu B., Langley E., Maguire S.F., Laird G.K., Lloyd D., Kenyon E., Donaldson S., Sehra H., Almeida-King J., Loveland J., Trevanion S., Jones M., Quail M., Willey D., Hunt A., Burton J., Sims S., McLay K., Plumb B., Davis J., Clee C., Oliver K., Clark R., Riddle C., Eliott D., Threadgold G., Harden G., Ware D., Mortimer B., Kerry G., Heath P., Phillimore B., Tracey A., Corby N., Dunn M., Johnson C., Wood J., Clark S., Pelan S., Griffiths G., Smith M., Glithero R., Howden P., Barker N., Stevens C., Harley J., Holt K., Panagiotidis G., Lovell J., Beasley H., Henderson C., Gordon D., Auger K., Wright D., Collins J., Raisen C., Dyer L., Leung K., Robertson L., Ambridge K., Leongamornlert D., McGuire S., Gilderthorp R., Griffiths C., Manthravadi D., Nichol S., Barker G., Whitehead S., Kay M., Brown J., Murnane C., Gray E., Humphries M., Sycamore N., Barker D., Saunders D., Wallis J., Babbage A., Hammond S., Mashreghi-Mohammadi M., Barr L., Martin S., Wray P., Ellington A., Matthews N., Ellwood M., Woodmansey R., Clark G., Cooper J., Tromans A., Grafham D., Skuce C., Pandian R., Andrews R., Harrison E., Kimberley A., Garnett J., Fosker N., Hall R., Garner P., Kelly D., Bird C., Palmer S., Gehring I., Berger A., Dooley C.M., Ersan-Urun Z., Eser C., Geiger H., Geisler M., Karotki L., Kirn A., Konantz J., Konantz M., Oberlander M., Rudolph-Geiger S., Teucke M., Osoegawa K., Zhu B., Rapp A., Widaa S., Langford C., Yang F., Carter N.P., Harrow J., Ning Z., Herrero J., Searle S.M., Enright A., Geisler R., Plasterk R.H., Lee C., Westerfield M., de Jong P.J., Zon L.I., Postlethwait J.H., Nusslein-Volhard C., Hubbard T.J., Roest Crollius H., Rogers J., Stemple D.L.
    Nature 496:498-503(2013) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: TuebingenImported.
  2. Ensembl
    Submitted (AUG-2013) to UniProtKB
    Cited for: IDENTIFICATION.
    Strain: TuebingenImported.

Entry informationi

Entry nameiQ1LUC3_DANRE
AccessioniPrimary (citable) accession number: Q1LUC3
Entry historyi
Integrated into UniProtKB/TrEMBL: May 30, 2006
Last sequence update: May 30, 2006
Last modified: October 29, 2014
This is version 66 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3