Reviewed, UniProtKB/Swiss-Prot Q1LU73 (G6PI_BAUCH)

Names and origin

Protein names

Recommended name:
    Glucose-6-phosphate isomerase
      Short name=GPI
    EC=5.3.1.9
Alternative name(s):
    Phosphoglucose isomerase
      Short name=PGI
    Phosphohexose isomerase
      Short name=PHI

Gene names

Name:	pgi
Ordered Locus Names:	BCI_0012

Organism

Baumannia cicadellinicola subsp. Homalodisca coagulata [Complete proteome] [HAMAP]

Taxonomic identifier

374463 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Candidatus Baumannia

Protein attributes

Sequence length	553 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Catalytic activity	D-glucose 6-phosphate = D-fructose 6-phosphate. HAMAP MF_00473
Pathway	Carbohydrate degradation; glycolysis; D-glyceraldehyde 3-phosphate and glycerone phosphate from D-glucose: step 2/4. HAMAP MF_00473
Subcellular location	Cytoplasm By similarity.
Sequence similarities	Belongs to the GPI family.

Ontologies

Keywords
Biological process	Gluconeogenesis Glycolysis
Cellular component	Cytoplasm
Molecular function	Isomerase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	gluconeogenesis Inferred from electronic annotation. Source: HAMAP glycolysis Inferred from electronic annotation. Source: HAMAP
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	glucose-6-phosphate isomerase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 553	553	Glucose-6-phosphate isomerase HAMAP MF_00473		PRO_0000252609
Sites
	Active site	355	1	Proton donor By similarity
	Active site	386	1	By similarity
	Active site	513	1	By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q1LU73-1 [UniParc]. Last modified May 30, 2006. Version 1. Checksum: C23A5A65CE9E2C89	FASTA	553	62,871
	10 20 30 40 50 60 MKNINPINTN AWNSLQQHFN NIKEVKIRDL FLLDSQRFDN FSAIFDNQIL LDYSKNRITT 70 80 90 100 110 120 ETLYLLFALA KECDLPNAIA AMFSGQKINR TEDRAVLHIA LRNRSNKIIA IDSQDIMPEV 130 140 150 160 170 180 NAVLSKMRQF CNQIISGQWK GYTGKPITNI VNIGIGGSDL GPYMVTEALR PYKNHLNMHF 190 200 210 220 230 240 VSNVDGTHIT EKFKYLDPET TLFLIASKTF TTQETMTNAH SARNWFLKTA VNEQYIAQHF 250 260 270 280 290 300 VAISTNANDV VKFGININNM FQFWDWVGGR YSLWSAIGLS IALSLGFENF ELLLEGAHAM 310 320 330 340 350 360 DCHFTETQLE HNLPVILALI NIWYNNFFGF ETEAIIPYDQ YMHRFAAYLQ QCHMESNGKS 370 380 390 400 410 420 IDRNGNIINY QTGSIIWGEP GTNSQHSFYQ LLHQGTKIVP CDFIVPAISH NPLGDHHLKL 430 440 450 460 470 480 LANCFAQTEA LAFGKSCQFI EEKFIMGTTS EQKLSIIPFK VCGGNRPTNS ILVKQITPYN 490 500 510 520 530 540 LGALISLYEH KIFTQSVILN IYAFDQWGVE LGKTQANSVL SELATDNIVT CHNSSTNGLI 550 NYYKSWRYKT DDK

References

[1]

"Metabolic complementarity and genomics of the dual bacterial symbiosis of sharpshooters." Wu D., Daugherty S.C., Van Aken S.E., Pai G.H., Watkins K.L., Khouri H., Tallon L.J., Zaborsky J.M., Dunbar H.E., Tran P.L., Moran N.A., Eisen J.A. PLoS Biol. 4:1079-1092(2006) [PubMed: 16729848] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBLGenBankDDBJ	CP000238 Genomic DNA. Translation: ABF13982.1.
RefSeq	YP_588491.1.
3D structure databases
ModBase	Search...
Genome annotation databases
GeneID	4056412.
GenomeReviews	Gene locus BCI_0012 in contig CP000238_GR.
KEGG	bci:BCI_0012.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	Q1LU73.
OMA	Q1LU73. GPKIVSQ.
Family and domain databases
HAMAP	MF_00473. [Tree]
InterPro	IPR001672. G6P_Isomerase. IPR018189. Phosphoglucose_isomerase_CS. [Graphical view]
PANTHER	PTHR11469. G6P_Isomerase. 1 hit.
Pfam	PF00342. PGI. 1 hit. [Graphical view]
PRINTS	PR00662. G6PISOMERASE.
PROSITE	PS00765. P_GLUCOSE_ISOMERASE_1. 1 hit. PS00174. P_GLUCOSE_ISOMERASE_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

G6PI_BAUCH

Accession

Primary (citable) accession number: Q1LU73

Entry history

Integrated into UniProtKB/Swiss-Prot:	October 17, 2006
Last sequence update:	May 30, 2006
Last modified:	June 16, 2009
This is version 21 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)