Reviewed, UniProtKB/Swiss-Prot Q1LU72 (PCKA_BAUCH)

Names and origin

Protein names

Recommended name:
    Phosphoenolpyruvate carboxykinase [ATP]
      Short name=PEP carboxykinase
      Short name=PEPCK
    EC=4.1.1.49
Alternative name(s):
    Phosphoenolpyruvate carboxylase

Gene names

Name:	pckA
Ordered Locus Names:	BCI_0013

Organism

Baumannia cicadellinicola subsp. Homalodisca coagulata [Complete proteome] [HAMAP]

Taxonomic identifier

374463 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Candidatus Baumannia

Protein attributes

Sequence length	538 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Catalytic activity	ATP + oxaloacetate = ADP + phosphoenolpyruvate + CO2. HAMAP MF_00453
Pathway	Carbohydrate biosynthesis; gluconeogenesis. HAMAP MF_00453
Subcellular location	Cytoplasm By similarity.
Sequence similarities	Belongs to the phosphoenolpyruvate carboxykinase [ATP] family.

Ontologies

Keywords
Biological process	Gluconeogenesis
Cellular component	Cytoplasm
Ligand	ATP-binding Nucleotide-binding
Molecular function	Decarboxylase Lyase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	gluconeogenesis Inferred from electronic annotation. Source: HAMAP
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	ATP binding Inferred from electronic annotation. Source: HAMAP phosphoenolpyruvate carboxykinase (ATP) activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 538	538	Phosphoenolpyruvate carboxykinase [ATP] HAMAP MF_00453		PRO_1000026316
Regions
	Nucleotide binding	246 – 253	8	ATP By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q1LU72-1 [UniParc]. Last modified May 30, 2006. Version 1. Checksum: F9AAA596370BBA5C	FASTA	538	60,040
	10 20 30 40 50 60 MLSNNIIRQQ LIHYGITDCC ELIYNPSFEQ LVREETNHNL TNLERGTITN SGAIAVNTGI 70 80 90 100 110 120 FTGRSPLDKY IVCDNDTHHQ LWWSDQDKTS NNQPISQITW QYLKKLVSKQ LSYKRLFIID 130 140 150 160 170 180 VYCGAKKNSR LRVRFVTEVA WQAHFVKNMF IQPDAIDLIS FEPEFIVLNG AKCTNPNWRE 190 200 210 220 230 240 QNMHSENFIA LNLTEGMQLI AGTWYGGEMK KGLFTVMNYH LPLKGIASMH CSANVGINKD 250 260 270 280 290 300 VALFFGLSGT GKTTLSHDTN RALIGDDEHG WDNDGIFNLE GGCYAKTINL KPELEPEIFQ 310 320 330 340 350 360 AIRCNALLEN VMVRADGSVN YHDNSKTDNA RVSYPLNHIK NRVQPVSCAS HASTIIFLTA 370 380 390 400 410 420 DAFGVLPPVA TLTNEQAQYY FLSGFSAKLS GTERGIISPV PTFSACFGAA FLALHPTVYA 430 440 450 460 470 480 ALLAKRMNIA GTNAYLVNTG WNGNGSRIAL KDTKAIINAI LNKQIQDTPT IKLPIFNLSI 490 500 510 520 530 PQILIGVDSN ILDPRTSYIN SSEWQNKARS LAQLFIKNFN KFTLPLTCKK LHNAGPQL

References

[1]

"Metabolic complementarity and genomics of the dual bacterial symbiosis of sharpshooters." Wu D., Daugherty S.C., Van Aken S.E., Pai G.H., Watkins K.L., Khouri H., Tallon L.J., Zaborsky J.M., Dunbar H.E., Tran P.L., Moran N.A., Eisen J.A. PLoS Biol. 4:1079-1092(2006) [PubMed: 16729848] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBLGenBankDDBJ	CP000238 Genomic DNA. Translation: ABF13999.1.
RefSeq	YP_588492.1.
3D structure databases
ModBase	Search...
Genome annotation databases
GeneID	4056747.
GenomeReviews	Gene locus BCI_0013 in contig CP000238_GR.
KEGG	bci:BCI_0013.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	Q1LU72.
OMA	Q1LU72. MFIRPTE.
Family and domain databases
HAMAP	MF_00453. [Tree]
InterPro	IPR001272. PEP_carboxykinase_ATP. IPR013035. PEP_carboxykinase_C. IPR008210. PEP_carboxykinase_N. IPR015994. PEPCK_ATP_CS. [Graphical view]
Gene3D	G3DSA:3.90.228.20. PEP_carboxykinase_C. 1 hit. G3DSA:3.40.449.10. PEP_carboxykinase_N. 1 hit.
Pfam	PF01293. PEPCK_ATP. 1 hit. [Graphical view]
PIRSF	PIRSF006294. PEP_crbxkin. 1 hit.
ProDom	PD004738. PEPCK_N. 1 hit. [Graphical view] [Entries sharing at least one domain]
TIGRFAMs	TIGR00224. pckA. 1 hit.
PROSITE	PS00532. PEPCK_ATP. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

PCKA_BAUCH

Accession

Primary (citable) accession number: Q1LU72

Entry history

Integrated into UniProtKB/Swiss-Prot:	January 15, 2008
Last sequence update:	May 30, 2006
Last modified:	June 16, 2009
This is version 22 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)