Q1LU65 (PLSB_BAUCH) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Glycerol-3-phosphate acyltransferase
Short name=GPAT
EC=2.3.1.15

Gene names

Name:	plsB
Ordered Locus Names:	BCI_0020

Organism

Baumannia cicadellinicola subsp. Homalodisca coagulata [Complete proteome] [HAMAP]

Taxonomic identifier

374463 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Candidatus Baumannia

Protein attributes

Sequence length	821 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	Acyl-CoA + sn-glycerol 3-phosphate = CoA + 1-acyl-sn-glycerol 3-phosphate. HAMAP MF_00393
Pathway	Phospholipid metabolism; CDP-diacylglycerol biosynthesis; CDP-diacylglycerol from sn-glycerol 3-phosphate: step 1/3. HAMAP MF_00393
Subcellular location	Cell membrane; Peripheral membrane protein; Cytoplasmic side By similarity HAMAP MF_00393.
Domain	The HXXXXD motif is essential for acyltransferase activity and may constitute the binding site for the phosphate moiety of the glycerol-3-phosphate By similarity. HAMAP MF_00393
Sequence similarities	Belongs to the GPAT/DAPAT family.

Ontologies

Keywords
Biological process	Phospholipid biosynthesis
Cellular component	Cell membrane Membrane
Molecular function	Acyltransferase Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	phospholipid biosynthetic process Inferred from electronic annotation. Source: UniProtKB-KW
Cellular component	plasma membrane Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	glycerol-3-phosphate O-acyltransferase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 821	821	Glycerol-3-phosphate acyltransferase HAMAP MF_00393		PRO_1000049428
Regions
	Motif	310 – 315	6	HXXXXD motif HAMAP MF_00393

Sequences

	Sequence		Length	Mass (Da)
	Q1LU65 [UniParc]. Last modified May 30, 2006. Version 1. Checksum: 64771BE4E3CE7524	FASTA	821	95,185
	10 20 30 40 50 60 MFNWRAIYNK ILYLLLKIVV RSHIIPPKLL AEICLDIQEP MMYVLPYNSK CDLLTLRILC 70 80 90 100 110 120 IQYQLPDPLK PIFIXGVRFP RYLFIDQSCH IRSDVTKQQQ YGRILHNFIT LYRHNSCSNI 130 140 150 160 170 180 QILPVWVMFG RCPGKESYKN KKTTSIQFFC LLKKIINVIW LGRDSFIYFS PIGSIPISYI 190 200 210 220 230 240 ANSNYTINSI MILKLFRLGR IHFLRQKRIA IGPSLLVRKH LFEKLLASQT ITKLVEDEAR 250 260 270 280 290 300 SKKISIKQAQ QKALVIIEEI AADFSYETIR LSDRVLSWIW NMLYQGLYVC NADRVRKLAE 310 320 330 340 350 360 KGHEIIYLPC HRSHMDYLLL SYILYHEGLV IPYIAAGINL NFWPAGQIFR KLGAFFIHRT 370 380 390 400 410 420 FKGHQKLYSA IFREYLYQLF NGGYSVAYFL EGSRSRTGRL QAPKTGTLTI TIQSMLHLGK 430 440 450 460 470 480 KKPIILVPVY ISYEHVIEVA SYTKELYGVV KKKEGLIHMI SGLRNLRNLG RGYINFGEPL 490 500 510 520 530 540 PLLTWLNQQV PQWQDDINSI EGNRPNWLAL TVDYLAVTIM TRINNAVAVN AMNLCSSIIL 550 560 570 580 590 600 ASRQYSCSSI VITRTRLLSQ LKCYLELLRN VPYDAEVTVP NVTPEDLFQH LITLNQFTIK 610 620 630 640 650 660 NNSIIYVSSE KTALITYYRN NIQHLFILPS LLAIIIIAQP GISRKLIHQK LLSLYPLLKV 670 680 690 700 710 720 ELFMRFSYQE LPHVIDLMIT ELHRQDILYE QQTKIYPVPK RMDELQLLAA SGGRETLYRY 730 740 750 760 770 780 AITFSLLCSY TRINRYSLEK QSIIIAQHLS KIHSIYALEF IDKTIFSTLI TTLRHEGYLS 790 800 810 820 DSGEIHASQA KEIYKFLSAL ISPEIQTSIT NALYHIKTVV N

References

[1]

"Metabolic complementarity and genomics of the dual bacterial symbiosis of sharpshooters." Wu D., Daugherty S.C., Van Aken S.E., Pai G.H., Watkins K.L., Khouri H., Tallon L.J., Zaborsky J.M., Dunbar H.E., Tran P.L., Moran N.A., Eisen J.A. PLoS Biol. 4:1079-1092(2006) [PubMed: 16729848] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000238 Genomic DNA. Translation: ABF13834.1.
RefSeq	YP_588499.1. NC_007984.1.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	Q1LU65.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	4056612.
GenomeReviews	Gene locus BCI_0020 in contig CP000238_GR.
KEGG	bci:BCI_0020.
PATRIC	21073527. VBIBauCic75062_0020.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG2937.
HOGENOM	HBG296590.
OMA	WNKLYQG.
Enzyme and pathway databases
BioCyc	BCIC186490:BCI_0020-MONOMER.
Family and domain databases
HAMAP	MF_00393. Glyc3P_acyltrans. [Tree]
InterPro	IPR002123. Acyltransferase. IPR022284. G3P_O-AcylTrfase. [Graphical view]
KO	K00631.
Pfam	PF01553. Acyltransferase. 1 hit. [Graphical view]
PIRSF	PIRSF000437. GPAT_DHAPAT. 1 hit.
SMART	SM00563. PlsC. 1 hit. [Graphical view]
TIGRFAMs	TIGR03703. PlsB. 1 hit.
ProtoNet	Search...

Entry information

Entry name

PLSB_BAUCH

Accession

Primary (citable) accession number: Q1LU65

Entry history

Integrated into UniProtKB/Swiss-Prot:	January 15, 2008
Last sequence update:	May 30, 2006
Last modified:	January 25, 2012
This is version 38 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program