Skip Header

Contribute Send feedback
Read comments (?) or add your own

Q1LU62 (AROB_BAUCH) Reviewed, UniProtKB/Swiss-Prot

Last modified January 25, 2012. Version 44. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
3-dehydroquinate synthase
EC=4.2.3.4
Gene names
Name:aroB
Ordered Locus Names:BCI_0023
OrganismBaumannia cicadellinicola subsp. Homalodisca coagulata [Complete proteome] [HAMAP]
Taxonomic identifier374463 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Gammaproteobacteria › Candidatus Baumannia

Protein attributes

Sequence length359 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

3-deoxy-D-arabino-hept-2-ulosonate 7-phosphate = 3-dehydroquinate + phosphate. HAMAP MF_00110

Cofactor

Divalent metal cations By similarity. HAMAP MF_00110

NAD By similarity. HAMAP MF_00110

Pathway

Metabolic intermediate biosynthesis; chorismate biosynthesis; chorismate from D-erythrose 4-phosphate and phosphoenolpyruvate: step 2/7. HAMAP MF_00110

Subunit structure

Monomer By similarity. HAMAP MF_00110

Subcellular location

Cytoplasm By similarity HAMAP MF_00110.

Sequence similarities

Belongs to the dehydroquinate synthase family.

Ontologies

Keywords
   Biological processAmino-acid biosynthesis
Aromatic amino acid biosynthesis
   Cellular componentCytoplasm
   LigandNAD
   Molecular functionLyase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processaromatic amino acid family biosynthetic process

Inferred from electronic annotation. Source: UniProtKB-KW

   Cellular componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular function3-dehydroquinate synthase activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 3593593-dehydroquinate synthase HAMAP MF_00110
PRO_1000094462

Sequences

Sequence LengthMass (Da)Tools
Q1LU62 [UniParc].

Last modified May 30, 2006. Version 1.
Checksum: 1060A952ABBC8746

FASTA35939,636
        10         20         30         40         50         60 
MDRISITLGE RSYAIIIANG LLQDPTSFWP LARGDKVLVV TSNYIASLYL EILSQILTEL 

        70         80         90        100        110        120 
GIIIDLCILP DGEQYKSLAM IDKIFTALLK KYHNNDTTII AFGGGVIGDL AGFAAANYLR 

       130        140        150        160        170        180 
GVRIIQIPTT LLSQVDSSVG GKTAVNHPLG KNMIGTIYQP TSVIIDPNCL ATLPRRELSS 

       190        200        210        220        230        240 
GLAEVIKYGI LFDVNFFNWL ELNIDALLGL EPHTVTWCIR RCCEIKAKIV TADEHEKGVR 

       250        260        270        280        290        300 
TLLNLGHTYG HAIETHMGYG NWLHGEAVAV GIMIVVQVSC SLGYFSNVDT ERVKTLLLRA 

       310        320        330        340        350 
GLPVIGPMKI SLEDYLPYIM RDKKTTNGIL HIILPLKLGS AEVHTYRISE WQKLIAHLI

« Hide

References

[1]"Metabolic complementarity and genomics of the dual bacterial symbiosis of sharpshooters."
Wu D., Daugherty S.C., Van Aken S.E., Pai G.H., Watkins K.L., Khouri H., Tallon L.J., Zaborsky J.M., Dunbar H.E., Tran P.L., Moran N.A., Eisen J.A.
PLoS Biol. 4:1079-1092(2006) [PubMed: 16729848] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000238 Genomic DNA. Translation: ABF14084.1.
RefSeqYP_588502.1. NC_007984.1.

3D structure databases

ProteinModelPortalQ1LU62.
ModBaseSearch...

Protein-protein interaction databases

STRINGQ1LU62.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID4056233.
GenomeReviewsGene locus BCI_0023 in contig CP000238_GR.
KEGGbci:BCI_0023.
PATRIC21073533. VBIBauCic75062_0023.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0337.
HOGENOMHBG632303.
OMAVMALEMS.
PhylomeDBQ1LU62.

Enzyme and pathway databases

BioCycBCIC186490:BCI_0023-MONOMER.

Family and domain databases

HAMAPMF_00110. DHQ_synthase.
[Tree]
InterProIPR016037. DHQ_synth_AroB.
[Graphical view]
KOK01735.
PANTHERPTHR21090:SF1. DHQ_synth_AroB. 1 hit.
PIRSFPIRSF001455. DHQ_synth. 1 hit.
TIGRFAMsTIGR01357. AroB. 1 hit.
ProtoNetSearch...

Entry information

Entry nameAROB_BAUCH
AccessionPrimary (citable) accession number: Q1LU62
Entry history
Integrated into UniProtKB/Swiss-Prot: March 24, 2009
Last sequence update: May 30, 2006
Last modified: January 25, 2012
This is version 44 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·Documents