Reviewed, UniProtKB/Swiss-Prot Q1LTZ4 (SUCC_BAUCH)

Names and origin

Protein names

Recommended name:
    Succinyl-CoA ligase [ADP-forming] subunit beta
    EC=6.2.1.5
Alternative name(s):
    Succinyl-CoA synthetase subunit beta
      Short name=SCS-beta

Gene names

Name:	sucC
Ordered Locus Names:	BCI_0097

Organism

Baumannia cicadellinicola subsp. Homalodisca coagulata [Complete proteome] [HAMAP]

Taxonomic identifier

374463 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Candidatus Baumannia

Protein attributes

Sequence length	393 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Catalytic activity	ATP + succinate + CoA = ADP + phosphate + succinyl-CoA. HAMAP MF_00558
Cofactor	Binds 1 magnesium or manganese ion per subunit By similarity.
Pathway	Carbohydrate metabolism; tricarboxylic acid cycle. HAMAP MF_00558
Subunit structure	Heterotetramer of two alpha and two beta subunits By similarity.
Sequence similarities	Belongs to the succinate/malate CoA ligase beta subunit family. Contains 1 ATP-grasp domain.

Ontologies

Keywords
Biological process	Tricarboxylic acid cycle
Ligand	ATP-binding Magnesium Manganese Metal-binding Nucleotide-binding
Molecular function	Ligase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	tricarboxylic acid cycle Inferred from electronic annotation. Source: HAMAP
Molecular function	ATP binding Inferred from electronic annotation. Source: HAMAP magnesium ion binding Inferred from electronic annotation. Source: UniProtKB-KW manganese ion binding Inferred from electronic annotation. Source: UniProtKB-KW succinate-CoA ligase (ADP-forming) activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 393	393	Succinyl-CoA ligase [ADP-forming] subunit beta HAMAP MF_00558		PRO_1000082022
Regions
	Domain	9 – 245	237	ATP-grasp
	Nucleotide binding	35 – 108	74	ATP By similarity
Sites
	Metal binding	198	1	Magnesium or manganese By similarity
	Metal binding	200	1	Magnesium or manganese By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q1LTZ4-1 [UniParc]. Last modified May 30, 2006. Version 1. Checksum: DC2255021012D409	FASTA	393	43,179
	10 20 30 40 50 60 MKLHEYQAKM LFAQYGIPIP KGLVCTTPNE AKESIAVIGY GPWIVKCQVH AGGRGKSGGV 70 80 90 100 110 120 RIVRSKEEIQ EFAKQWFGKH LITEQTNHIG QPVSKILVEA AIDIAQELYL GCLVDRSNQC 130 140 150 160 170 180 IKFIASIQGG IDIENIAKEK PHLLHQIILD PLIGPQLYQS RDLAFKIGLS SKKQINQFNK 190 200 210 220 230 240 IFMGLATLFL EKDLVMAEIN PLVITRLGDL ICLDGKLHVD SNALFRQPEL CKMLDPSQED 250 260 270 280 290 300 KCETYAKQHN LNYIALNGNI GCLVNGAGLA MSTIDMVKFY GGEPANFLDV GGRVTQEKVT 310 320 330 340 350 360 KAFQIILSDK KVKVILVNIF GGIVCCDVIA KGIINARLES GINIPVIVRL EGNNAKQGIQ 370 380 390 HLVNSILNIR IATNLTTAAK QAVALVEGKQ CLF

References

[1]

"Metabolic complementarity and genomics of the dual bacterial symbiosis of sharpshooters." Wu D., Daugherty S.C., Van Aken S.E., Pai G.H., Watkins K.L., Khouri H., Tallon L.J., Zaborsky J.M., Dunbar H.E., Tran P.L., Moran N.A., Eisen J.A. PLoS Biol. 4:1079-1092(2006) [PubMed: 16729848] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBLGenBankDDBJ	CP000238 Genomic DNA. Translation: ABF14132.1.
RefSeq	YP_588570.1.
3D structure databases
ModBase	Search...
Genome annotation databases
GeneID	4056318.
GenomeReviews	Gene locus BCI_0097 in contig CP000238_GR.
KEGG	bci:BCI_0097.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	Q1LTZ4.
OMA	Q1LTZ4. NLHCLDA.
Family and domain databases
HAMAP	MF_00558. [Tree]
InterPro	IPR011761. ATP-grasp. IPR013650. ATP-grasp_succ-CoA_synth-type. IPR013816. ATP_grasp_subdomain_2. IPR005811. CoA_ligase. IPR017866. Succ-CoA_synthase_bsu_CS. IPR005809. Succ_CoA_synthase_bsu. IPR016102. Succinyl-CoA_synth-like. [Graphical view]
Gene3D	G3DSA:3.30.470.20. ATP_grasp_subdomain_2. 1 hit. G3DSA:3.40.50.261. Succinyl-CoA_synth-like. 1 hit.
PANTHER	PTHR11815. CoA_lig_beta. 1 hit.
Pfam	PF08442. ATP-grasp_2. 1 hit. PF00549. Ligase_CoA. 1 hit. [Graphical view]
TIGRFAMs	TIGR01016. sucCoAbeta. 1 hit.
PROSITE	PS50975. ATP_GRASP. 1 hit. PS01217. SUCCINYL_COA_LIG_3. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

SUCC_BAUCH

Accession

Primary (citable) accession number: Q1LTZ4

Entry history

Integrated into UniProtKB/Swiss-Prot:	May 20, 2008
Last sequence update:	May 30, 2006
Last modified:	June 16, 2009
This is version 24 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)