Q1LTY3 (KGUA_BAUCH) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Guanylate kinase
EC=2.7.4.8

Alternative name(s):
GMP kinase

Gene names

Name:	gmk
Ordered Locus Names:	BCI_0110

Organism

Baumannia cicadellinicola subsp. Homalodisca coagulata [Complete proteome] [HAMAP]

Taxonomic identifier

374463 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › Gammaproteobacteria › unclassified Gammaproteobacteria › Candidatus Baumannia › Candidatus Baumannia cicadellinicola

Protein attributes

Sequence length	204 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Essential for recycling GMP and indirectly, cGMP By similarity. HAMAP-Rule MF_00328
Catalytic activity	ATP + GMP = ADP + GDP. HAMAP-Rule MF_00328
Subcellular location	Cytoplasm By similarity.
Sequence similarities	Belongs to the guanylate kinase family. Contains 1 guanylate kinase-like domain.

Ontologies

Keywords
Cellular component	Cytoplasm
Ligand	ATP-binding Nucleotide-binding
Molecular function	Kinase Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	purine nucleotide metabolic process Inferred from electronic annotation. Source: InterPro
Cellular_component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular_function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW guanylate kinase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 204	204	Guanylate kinase HAMAP-Rule MF_00328		PRO_0000266290
Regions
	Domain	1 – 182	182	Guanylate kinase-like
	Nucleotide binding	7 – 14	8	ATP By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q1LTY3 [UniParc]. Last modified May 30, 2006. Version 1. Checksum: 9C758B4073902923	FASTA	204	23,915
	10 20 30 40 50 60 MLYIISAPSG TGKSSLLQAL LRTKRLPLHE IRISISHTTR AMRPGEINGQ HYYFISVEEF 70 80 90 100 110 120 EKLIDQDAFL EYARVFNHYY GTLRQEVDSI LINSVDILLD IDWQGAKQIY AIRKDVRSIF 130 140 150 160 170 180 IIPPSKDELH RRLHKRGQDQ EEVINQRISQ AVAEMIHYTE YDYLIINDDF HTALSDLNTI 190 200 ICAEQLHMNN QKIRYKTLIS RLLQ

References

[1]

"Metabolic complementarity and genomics of the dual bacterial symbiosis of sharpshooters." Wu D., Daugherty S.C., Van Aken S.E., Pai G.H., Watkins K.L., Khouri H., Tallon L.J., Zaborsky J.M., Dunbar H.E., Tran P.L., Moran N.A., Eisen J.A. PLoS Biol. 4:1079-1092(2006) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000238 Genomic DNA. Translation: ABF14262.1.
RefSeq	YP_588581.1. NC_007984.1.
3D structure databases
ProteinModelPortal	Q1LTY3.
SMR	Q1LTY3. Positions 2-203.
ModBase	Search...
Protein-protein interaction databases
STRING	374463.BCI_0110.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	ABF14262; ABF14262; BCI_0110.
GeneID	4056446.
KEGG	bci:BCI_0110.
PATRIC	21073713. VBIBauCic75062_0108.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0194.
HOGENOM	HOG000037638.
KO	K00942.
OMA	FVIINEL.
Enzyme and pathway databases
BioCyc	BCIC374463:GI6Q-151-MONOMER.
Family and domain databases
HAMAP	MF_00328. Guanylate_kinase.
InterPro	IPR008144. Guanylate_kin. IPR008145. Guanylate_kin/L-typ_Ca_channel. IPR020590. Guanylate_kinase_CS. IPR017665. Guanylate_kinase_sub. [Graphical view]
Pfam	PF00625. Guanylate_kin. 1 hit. [Graphical view]
SMART	SM00072. GuKc. 1 hit. [Graphical view]
TIGRFAMs	TIGR03263. guanyl_kin. 1 hit.
PROSITE	PS00856. GUANYLATE_KINASE_1. 1 hit. PS50052. GUANYLATE_KINASE_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

KGUA_BAUCH

Accession

Primary (citable) accession number: Q1LTY3

Entry history

Integrated into UniProtKB/Swiss-Prot:	December 12, 2006
Last sequence update:	May 30, 2006
Last modified:	May 1, 2013
This is version 41 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program