Q1LTX0 (DAPF_BAUCH) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Diaminopimelate epimerase
Short name=DAP epimerase
EC=5.1.1.7

Gene names

Name:	dapF
Ordered Locus Names:	BCI_0125

Organism

Baumannia cicadellinicola subsp. Homalodisca coagulata [Complete proteome] [HAMAP]

Taxonomic identifier

374463 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Candidatus Baumannia

Protein attributes

Sequence length	274 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	LL-2,6-diaminoheptanedioate = meso-diaminoheptanedioate. HAMAP MF_00197
Pathway	Amino-acid biosynthesis; L-lysine biosynthesis via DAP pathway; DL-2,6-diaminopimelate from LL-2,6-diaminopimelate: step 1/1. HAMAP MF_00197
Subcellular location	Cytoplasm By similarity HAMAP MF_00197.
Sequence similarities	Belongs to the diaminopimelate epimerase family.

Ontologies

Keywords
Biological process	Amino-acid biosynthesis Lysine biosynthesis
Cellular component	Cytoplasm
Molecular function	Isomerase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	lysine biosynthetic process via diaminopimelate Inferred from electronic annotation. Source: InterPro
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	diaminopimelate epimerase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 274	274	Diaminopimelate epimerase HAMAP MF_00197		PRO_1000058538
Sites
	Active site	73	1	By similarity
	Active site	217	1	By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q1LTX0 [UniParc]. Last modified May 30, 2006. Version 1. Checksum: 60E2349CB8D80347	FASTA	274	30,702
	10 20 30 40 50 60 MQFSKMHGLG NDFMVVDVVT QNVYLSPTKI RFLANRHSGV GFDQLLFVEP PYDPEIDFHY 70 80 90 100 110 120 RIFNADGSEV TQCGNGARCL AHFVRMKKLT NKREIYISTQ TSRMVLTIIE NNMVRVNMGV 130 140 150 160 170 180 PKFELPQIPF DMHQIEKKEI LYLAKNYIFG GIVSIGNPHC IMIVNNVDSA QVSIIGPILE 190 200 210 220 230 240 IHKYFSERTN VGFMQVINRE QVLLRVYERG VGETQACGSG ACAAVAIGIR LGLLAEQVQV 250 260 270 ALPGGKLVIY WRGPGQSLYM TGPAVHIYDG FIND

References

[1]

"Metabolic complementarity and genomics of the dual bacterial symbiosis of sharpshooters." Wu D., Daugherty S.C., Van Aken S.E., Pai G.H., Watkins K.L., Khouri H., Tallon L.J., Zaborsky J.M., Dunbar H.E., Tran P.L., Moran N.A., Eisen J.A. PLoS Biol. 4:1079-1092(2006) [PubMed: 16729848] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000238 Genomic DNA. Translation: ABF14159.1.
RefSeq	YP_588594.1. NC_007984.1.
3D structure databases
ProteinModelPortal	Q1LTX0.
SMR	Q1LTX0. Positions 1-272.
ModBase	Search...
Protein-protein interaction databases
STRING	Q1LTX0.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	4056212.
GenomeReviews	Gene locus BCI_0125 in contig CP000238_GR.
KEGG	bci:BCI_0125.
PATRIC	21073749. VBIBauCic75062_0125.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0253.
HOGENOM	HBG399442.
OMA	FMTGPAT.
PhylomeDB	Q1LTX0.
Enzyme and pathway databases
BioCyc	BCIC186490:BCI_0125-MONOMER.
Family and domain databases
HAMAP	MF_00197. DAP_epimerase. [Tree]
InterPro	IPR018510. DAP_epimerase_AS. IPR001653. DAP_epimerase_DapF. [Graphical view]
KO	K01778.
Pfam	PF01678. DAP_epimerase. 2 hits. [Graphical view]
TIGRFAMs	TIGR00652. DapF. 1 hit.
PROSITE	PS01326. DAP_EPIMERASE. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

DAPF_BAUCH

Accession

Primary (citable) accession number: Q1LTX0

Entry history

Integrated into UniProtKB/Swiss-Prot:	February 5, 2008
Last sequence update:	May 30, 2006
Last modified:	January 25, 2012
This is version 39 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program