ID   K6PF_BAUCH              Reviewed;         320 AA.
AC   Q1LTT2;
DT   05-FEB-2008, integrated into UniProtKB/Swiss-Prot.
DT   30-MAY-2006, sequence version 1.
DT   16-JUN-2009, entry version 29.
DE   RecName: Full=6-phosphofructokinase;
DE            Short=Phosphofructokinase;
DE            EC=2.7.1.11;
DE   AltName: Full=Phosphohexokinase;
GN   Name=pfkA; OrderedLocusNames=BCI_0171;
OS   Baumannia cicadellinicola subsp. Homalodisca coagulata.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Candidatus Baumannia.
OX   NCBI_TaxID=374463;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=16729848; DOI=10.1371/journal.pbio.0040188;
RA   Wu D., Daugherty S.C., Van Aken S.E., Pai G.H., Watkins K.L.,
RA   Khouri H., Tallon L.J., Zaborsky J.M., Dunbar H.E., Tran P.L.,
RA   Moran N.A., Eisen J.A.;
RT   "Metabolic complementarity and genomics of the dual bacterial
RT   symbiosis of sharpshooters.";
RL   PLoS Biol. 4:1079-1092(2006).
CC   -!- CATALYTIC ACTIVITY: ATP + D-fructose 6-phosphate = ADP + D-
CC       fructose 1,6-bisphosphate.
CC   -!- PATHWAY: Carbohydrate degradation; glycolysis; D-glyceraldehyde 3-
CC       phosphate and glycerone phosphate from D-glucose: step 3/4.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm (By similarity).
CC   -!- SIMILARITY: Belongs to the phosphofructokinase family.
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DR   EMBL; CP000238; ABF13987.1; -; Genomic_DNA.
DR   RefSeq; YP_588632.1; -.
DR   SMR; Q1LTT2; 1-320.
DR   GeneID; 4056734; -.
DR   GenomeReviews; CP000238_GR; BCI_0171.
DR   KEGG; bci:BCI_0171; -.
DR   HOGENOM; Q1LTT2; -.
DR   OMA; Q1LTT2; DTCLNTV.
DR   GO; GO:0005945; C:6-phosphofructokinase complex; IEA:InterPro.
DR   GO; GO:0003872; F:6-phosphofructokinase activity; IEA:HAMAP.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0000287; F:magnesium ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006002; P:fructose 6-phosphate metabolic process; IEA:InterPro.
DR   GO; GO:0006096; P:glycolysis; IEA:HAMAP.
DR   HAMAP; MF_00339; -; 1.
DR   InterPro; IPR012003; ATP_PFK_prok.
DR   InterPro; IPR012828; PFKA_ATP.
DR   InterPro; IPR000023; Phosphofructokinase.
DR   InterPro; IPR015912; Phosphofructokinase_CS.
DR   Pfam; PF00365; PFK; 1.
DR   PIRSF; PIRSF000532; ATP_PFK_prok; 1.
DR   PRINTS; PR00476; PHFRCTKINASE.
DR   ProDom; PD000707; Ppfruckinase; 1.
DR   TIGRFAMs; TIGR02482; PFKA_ATP; 1.
DR   PROSITE; PS00433; PHOSPHOFRUCTOKINASE; 1.
PE   3: Inferred from homology;
KW   ATP-binding; Complete proteome; Cytoplasm; Glycolysis; Kinase;
KW   Magnesium; Metal-binding; Nucleotide-binding; Transferase.
FT   CHAIN         1    320       6-phosphofructokinase.
FT                                /FTId=PRO_1000059747.
FT   NP_BIND      22     26       ATP (By similarity).
FT   NP_BIND     155    159       ATP (By similarity).
FT   NP_BIND     172    188       ATP (By similarity).
FT   ACT_SITE    128    128       Proton acceptor (By similarity).
FT   METAL       186    186       Magnesium; via carbonyl oxygen (By
FT                                similarity).
FT   METAL       188    188       Magnesium (By similarity).
FT   BINDING     163    163       Substrate (By similarity).
FT   BINDING     244    244       Substrate (By similarity).
FT   BINDING     250    250       Substrate (By similarity).
FT   BINDING     253    253       Substrate (By similarity).
SQ   SEQUENCE   320 AA;  35151 MW;  5D589CA6F26A332A CRC64;
     MINKIGVLTS GGDSPGMNAA IRSVVRAGLS EGLEIYGISD GYQGLYQDRM RKLDRYSVSD
     IINRGGTFLG SARFQEFREE AIRAIALNNM SKYGLGALVV IGGDGSYMGA KLLTEMGLPC
     IGLPGTIDND VAGTDYTIGY FTALETVVEA IDRLRDTSTS HQRISIVEVM GRYCGDLTMA
     AAIAGGCEFI VLPEVEFQPE DLVYEIKASI AQGKKHAIVA ITEYICNVFE LALYIEKETG
     RETRATVLGH IQRGGNPVAY DRILASRMGA YSIELLLQGY RGRCVGVQNE RLVHHDIADV
     IQNMKRPFRR DFLETARKLF
//