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Q1LTM9

- SYL_BAUCH

UniProt

Q1LTM9 - SYL_BAUCH

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Protein

Leucine--tRNA ligase

Gene

leuS

Organism
Baumannia cicadellinicola subsp. Homalodisca coagulata
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + L-leucine + tRNA(Leu) = AMP + diphosphate + L-leucyl-tRNA(Leu).UniRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei623 – 6231ATPUniRule annotation

GO - Molecular functioni

  1. aminoacyl-tRNA editing activity Source: InterPro
  2. ATP binding Source: UniProtKB-HAMAP
  3. leucine-tRNA ligase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. leucyl-tRNA aminoacylation Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Aminoacyl-tRNA synthetase, Ligase

Keywords - Biological processi

Protein biosynthesis

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciBCIC374463:GI6Q-232-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Leucine--tRNA ligaseUniRule annotation (EC:6.1.1.4UniRule annotation)
Alternative name(s):
Leucyl-tRNA synthetaseUniRule annotation
Short name:
LeuRSUniRule annotation
Gene namesi
Name:leuSUniRule annotation
Ordered Locus Names:BCI_0232
OrganismiBaumannia cicadellinicola subsp. Homalodisca coagulata
Taxonomic identifieri374463 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaCandidatus Baumannia
ProteomesiUP000002427: Chromosome

Subcellular locationi

Cytoplasm UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 861861Leucine--tRNA ligasePRO_1000009296Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi374463.BCI_0232.

Structurei

3D structure databases

ProteinModelPortaliQ1LTM9.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Motif

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Motifi42 – 5211"HIGH" regionAdd
BLAST
Motifi620 – 6245"KMSKS" region

Sequence similaritiesi

Belongs to the class-I aminoacyl-tRNA synthetase family.UniRule annotation

Phylogenomic databases

eggNOGiCOG0495.
HOGENOMiHOG000200748.
KOiK01869.
OMAiHISHELW.
OrthoDBiEOG63Z74X.

Family and domain databases

Gene3Di1.10.730.10. 1 hit.
3.40.50.620. 3 hits.
3.90.740.10. 1 hit.
HAMAPiMF_00049_B. Leu_tRNA_synth_B.
InterProiIPR001412. aa-tRNA-synth_I_CS.
IPR002300. aa-tRNA-synth_Ia.
IPR002302. Leu-tRNA-ligase.
IPR025709. Leu_tRNA-synth_edit.
IPR014729. Rossmann-like_a/b/a_fold.
IPR009080. tRNAsynth_1a_anticodon-bd.
IPR013155. V/L/I-tRNA-synth_anticodon-bd.
IPR009008. Val/Leu/Ile-tRNA-synth_edit.
[Graphical view]
PANTHERiPTHR11946:SF7. PTHR11946:SF7. 1 hit.
PfamiPF08264. Anticodon_1. 1 hit.
PF00133. tRNA-synt_1. 3 hits.
PF13603. tRNA-synt_1_2. 1 hit.
[Graphical view]
PRINTSiPR00985. TRNASYNTHLEU.
SUPFAMiSSF47323. SSF47323. 1 hit.
SSF50677. SSF50677. 1 hit.
TIGRFAMsiTIGR00396. leuS_bact. 1 hit.
PROSITEiPS00178. AA_TRNA_LIGASE_I. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q1LTM9-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MQEFYDPKNI ESTIQQYWHE NNTFTVTEDF SKEKYYCLSM LPYPSGNLHM
60 70 80 90 100
GHVRNYTIGD VLSRYHRMLG KNVMQPIGWD AFGLPAERAA LKNQTAPATW
110 120 130 140 150
TYANIETMKK QLKQLGFSYD WSREITTCRP EYYRWEQWFF IQLYEKGLVY
160 170 180 190 200
KKTSFVNWCS NDQTVLANEQ VIDGCCWRCG APIMLKDIPQ WFLKITAYAD
210 220 230 240 250
QLLHDLDKLD GWPEQIKNMQ RNWIGRSEGI NITFQVIDMK ETLTIYTTRP
260 270 280 290 300
DTLMGVTYLS IAINHHLAQQ AANNNRLLSD FIEHSRPTKL SEAEIVKVNR
310 320 330 340 350
VKTGIFTGLY AIHPLTEEKL PIWVTNFVLM DYGTGAIMAV PGHDQRDWDF
360 370 380 390 400
ARQYNLPVKN IIRNIDGSKP TISGIIPEGI LYNSGEFNGL RSLEASKIIT
410 420 430 440 450
DILVARGIGE TKVNYRLRDW VISRQRYWGT PIPMMTLEDG TVVPTPVDQL
460 470 480 490 500
PVILPEYLLI NSISNPLKDD HLWMKTNYNN NIATRETDTF DTFMESSWYY
510 520 530 540 550
ARYTCPNYDQ GMLDTTAANY WLPIDQYIGG IEHAIMHLMY FRFYHKLLRD
560 570 580 590 600
AGMLTSDEPT IRILCQGMVL ADSFYYISCT TGERIWVSPI NVRVQRDEKG
610 620 630 640 650
NIINAIDLQG HHLVYAGTIK MSKSKNNSID PLTMVEKYGA DTIRLFIMFA
660 670 680 690 700
SPVTMALEWR ESGVEGANRF LKRLWKLTYD HIQRGKVIKL DLAAMSNDNK
710 720 730 740 750
ILRRELHQTI AKVTDDISRR YAFNTAIAAL MEITNKLMHA SYHSQQDRAI
760 770 780 790 800
VQEALLAVVR MLYPFTPHLC FKLWQALNGE GDIDNAPWPI VDQLALVEDT
810 820 830 840 850
NLIVIQINGR FRSKIIVPVS ADKALIIERA SKEKLVAKYL EGTKVQKIIY
860
VPGKLLNLVL K
Length:861
Mass (Da):99,335
Last modified:May 30, 2006 - v1
Checksum:i151E545728E934B5
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000238 Genomic DNA. Translation: ABF13994.1.
RefSeqiYP_588685.1. NC_007984.1.

Genome annotation databases

EnsemblBacteriaiABF13994; ABF13994; BCI_0232.
GeneIDi4056741.
KEGGibci:BCI_0232.
PATRICi21073965. VBIBauCic75062_0221.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000238 Genomic DNA. Translation: ABF13994.1 .
RefSeqi YP_588685.1. NC_007984.1.

3D structure databases

ProteinModelPortali Q1LTM9.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 374463.BCI_0232.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ABF13994 ; ABF13994 ; BCI_0232 .
GeneIDi 4056741.
KEGGi bci:BCI_0232.
PATRICi 21073965. VBIBauCic75062_0221.

Phylogenomic databases

eggNOGi COG0495.
HOGENOMi HOG000200748.
KOi K01869.
OMAi HISHELW.
OrthoDBi EOG63Z74X.

Enzyme and pathway databases

BioCyci BCIC374463:GI6Q-232-MONOMER.

Family and domain databases

Gene3Di 1.10.730.10. 1 hit.
3.40.50.620. 3 hits.
3.90.740.10. 1 hit.
HAMAPi MF_00049_B. Leu_tRNA_synth_B.
InterProi IPR001412. aa-tRNA-synth_I_CS.
IPR002300. aa-tRNA-synth_Ia.
IPR002302. Leu-tRNA-ligase.
IPR025709. Leu_tRNA-synth_edit.
IPR014729. Rossmann-like_a/b/a_fold.
IPR009080. tRNAsynth_1a_anticodon-bd.
IPR013155. V/L/I-tRNA-synth_anticodon-bd.
IPR009008. Val/Leu/Ile-tRNA-synth_edit.
[Graphical view ]
PANTHERi PTHR11946:SF7. PTHR11946:SF7. 1 hit.
Pfami PF08264. Anticodon_1. 1 hit.
PF00133. tRNA-synt_1. 3 hits.
PF13603. tRNA-synt_1_2. 1 hit.
[Graphical view ]
PRINTSi PR00985. TRNASYNTHLEU.
SUPFAMi SSF47323. SSF47323. 1 hit.
SSF50677. SSF50677. 1 hit.
TIGRFAMsi TIGR00396. leuS_bact. 1 hit.
PROSITEi PS00178. AA_TRNA_LIGASE_I. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Metabolic complementarity and genomics of the dual bacterial symbiosis of sharpshooters."
    Wu D., Daugherty S.C., Van Aken S.E., Pai G.H., Watkins K.L., Khouri H., Tallon L.J., Zaborsky J.M., Dunbar H.E., Tran P.L., Moran N.A., Eisen J.A.
    PLoS Biol. 4:1079-1092(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Entry informationi

Entry nameiSYL_BAUCH
AccessioniPrimary (citable) accession number: Q1LTM9
Entry historyi
Integrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: May 30, 2006
Last modified: October 29, 2014
This is version 68 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Aminoacyl-tRNA synthetases
    List of aminoacyl-tRNA synthetase entries
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3