Reviewed, UniProtKB/Swiss-Prot Q1LTL1 (AROA_BAUCH)

Names and origin

Protein names

Recommended name:
    3-phosphoshikimate 1-carboxyvinyltransferase
    EC=2.5.1.19
Alternative name(s):
    5-enolpyruvylshikimate-3-phosphate synthase
      Short name=EPSP synthase
      Short name=EPSPS

Gene names

Name:	aroA
Ordered Locus Names:	BCI_0253

Organism

Baumannia cicadellinicola subsp. Homalodisca coagulata [Complete proteome] [HAMAP]

Taxonomic identifier

374463 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Candidatus Baumannia

Protein attributes

Sequence length	428 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Catalytic activity	Phosphoenolpyruvate + 3-phosphoshikimate = phosphate + 5-O-(1-carboxyvinyl)-3-phosphoshikimate. HAMAP MF_00210
Pathway	Metabolic intermediate biosynthesis; chorismate biosynthesis; chorismate from D-erythrose 4-phosphate and phosphoenolpyruvate: step 6/7. HAMAP MF_00210
Subunit structure	Monomer By similarity.
Subcellular location	Cytoplasm Probable.
Sequence similarities	Belongs to the EPSP synthase family.

Ontologies

Keywords
Biological process	Amino-acid biosynthesis Aromatic amino acid biosynthesis
Cellular component	Cytoplasm
Molecular function	Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	aromatic amino acid family biosynthetic process Inferred from electronic annotation. Source: HAMAP
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	3-phosphoshikimate 1-carboxyvinyltransferase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 428	428	3-phosphoshikimate 1-carboxyvinyltransferase HAMAP MF_00210		PRO_1000012409

Sequences

	Sequence		Length	Mass (Da)
	Q1LTL1-1 [UniParc]. Last modified May 30, 2006. Version 1. Checksum: F4F4B236E7F24E97	FASTA	428	47,440
	10 20 30 40 50 60 MQELLTLQPI VRVNGTIHLP GSKSISNRAL LLAAQALGKT CLINLLDSYD VRYMLDALHK 70 80 90 100 110 120 LGINYCLSID RRSCEIDGIG RPLRVDTALE LYLGNSGIAL RSLVAALCLQ NKNIIITGDK 130 140 150 160 170 180 RMKNRPIGHL VDALRQGSAQ IHYLEKDNYP PLLLQGGFYN GDITIDCSLS SQFLTSLLMM 190 200 210 220 230 240 APLASQDRCI FVKGRLVSKP YIDMTLAMMK SFGIVVQHDQ YKIFYIKGKS QYRSPGHYLV 250 260 270 280 290 300 EGDATNASYF LAAAAIRGGT VRVTGVGSNS IQGDIRFADI LANMGAIIRW GVNYIECTRN 310 320 330 340 350 360 SLCSIDIDMN ALPDTAMTIA IVALFTYNGV TTLRNIYNWR IKETNRLVAM ATELRKVGAI 370 380 390 400 410 420 VVEGKEYLSI KPPNMFKIAK INTYDDHRIA MCFALVALSN VSITIVNPKC TYKTFPDFFK LLKGISIT

References

[1]

"Metabolic complementarity and genomics of the dual bacterial symbiosis of sharpshooters." Wu D., Daugherty S.C., Van Aken S.E., Pai G.H., Watkins K.L., Khouri H., Tallon L.J., Zaborsky J.M., Dunbar H.E., Tran P.L., Moran N.A., Eisen J.A. PLoS Biol. 4:1079-1092(2006) [PubMed: 16729848] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBLGenBankDDBJ	CP000238 Genomic DNA. Translation: ABF14261.1.
RefSeq	YP_588703.1.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	Q1LTL1.
Genome annotation databases
GeneID	4056445.
GenomeReviews	Gene locus BCI_0253 in contig CP000238_GR.
KEGG	bci:BCI_0253.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	Q1LTL1.
OMA	EIDTYND.
Family and domain databases
HAMAP	MF_00210. [Tree]
InterPro	IPR016228. EPSP_synthase. IPR001986. EPSP_synthase_core. IPR006264. EPSP_synthase_subgroup. [Graphical view]
Gene3D	G3DSA:3.65.10.10. EPSP_synthase. 2 hits.
Pfam	PF00275. EPSP_synthase. 1 hit. [Graphical view]
PIRSF	PIRSF000505. EPSPS. 1 hit.
ProDom	PD001867. EPSP_synth. 1 hit. [Graphical view] [Entries sharing at least one domain]
TIGRFAMs	TIGR01356. aroA. 1 hit.
PROSITE	PS00104. EPSP_SYNTHASE_1. 1 hit. PS00885. EPSP_SYNTHASE_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

AROA_BAUCH

Accession

Primary (citable) accession number: Q1LTL1

Entry history

Integrated into UniProtKB/Swiss-Prot:	January 15, 2008
Last sequence update:	May 30, 2006
Last modified:	November 3, 2009
This is version 31 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)