Reviewed, UniProtKB/Swiss-Prot Q1LTI6 (ACPS_BAUCH)

Names and origin

Protein names

Recommended name:
    Holo-[acyl-carrier-protein] synthase
      Short name=Holo-ACP synthase
    EC=2.7.8.7
Alternative name(s):
    4'-phosphopantetheinyl transferase acpS

Gene names

Name:	acpS
Ordered Locus Names:	BCI_0278

Organism

Baumannia cicadellinicola subsp. Homalodisca coagulata [Complete proteome] [HAMAP]

Taxonomic identifier

374463 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Candidatus Baumannia

Protein attributes

Sequence length	146 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Function	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein By similarity.
Catalytic activity	CoA-(4'-phosphopantetheine) + apo-[acyl-carrier-protein] = adenosine 3',5'-bisphosphate + holo-[acyl-carrier-protein]. HAMAP MF_00101
Cofactor	Magnesium By similarity.
Subcellular location	Cytoplasm By similarity.
Sequence similarities	Belongs to the P-Pant transferase superfamily. AcpS family.

Ontologies

Keywords
Biological process	Fatty acid biosynthesis Lipid synthesis
Cellular component	Cytoplasm
Ligand	Magnesium Metal-binding
Molecular function	Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	fatty acid biosynthetic process Inferred from electronic annotation. Source: HAMAP macromolecule biosynthetic process Inferred from electronic annotation. Source: InterPro
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	holo-[acyl-carrier-protein] synthase activity Inferred from electronic annotation. Source: HAMAP magnesium ion binding Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 146	146	Holo-[acyl-carrier-protein] synthase HAMAP MF_00101		PRO_1000008388
Sites
	Metal binding	9	1	Magnesium By similarity
	Metal binding	58	1	Magnesium By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q1LTI6-1 [UniParc]. Last modified May 30, 2006. Version 1. Checksum: 0A96818D3E2A5034	FASTA	146	16,865
	10 20 30 40 50 60 MAILGIGTDI VEIARIHTVL VRCGERFIDR ILSPIEYKQY HQQNNSVHFL AKRFAVKEAA 70 80 90 100 110 120 AKALGTGICH GIAFVQFELF HDERGKPQLR LHEQAAQLAR ERHITRMHVT LADERYYTCA 130 140 MVIFEGDIRS NDYSIQPNWY LSKIKP

References

[1]

"Metabolic complementarity and genomics of the dual bacterial symbiosis of sharpshooters." Wu D., Daugherty S.C., Van Aken S.E., Pai G.H., Watkins K.L., Khouri H., Tallon L.J., Zaborsky J.M., Dunbar H.E., Tran P.L., Moran N.A., Eisen J.A. PLoS Biol. 4:1079-1092(2006) [PubMed: 16729848] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBLGenBankDDBJ	CP000238 Genomic DNA. Translation: ABF14256.1.
RefSeq	YP_588728.1.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	Q1LTI6.
Genome annotation databases
GeneID	4056440.
GenomeReviews	Gene locus BCI_0278 in contig CP000238_GR.
KEGG	bci:BCI_0278.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	Q1LTI6.
OMA	DYAIAFI.
Family and domain databases
HAMAP	MF_00101. [Tree]
InterPro	IPR008278. 4-PPantetheinyl_Trfase. IPR002582. ACPS. IPR004568. PPantethiene-prot_Trfase. [Graphical view]
Pfam	PF01648. ACPS. 1 hit. [Graphical view]
ProDom	PD004282. ACPS. 1 hit. [Graphical view] [Entries sharing at least one domain]
TIGRFAMs	TIGR00516. acpS. 1 hit. TIGR00556. pantethn_trn. 1 hit.
ProtoNet	Search...

Entry information

Entry name

ACPS_BAUCH

Accession

Primary (citable) accession number: Q1LTI6

Entry history

Integrated into UniProtKB/Swiss-Prot:	January 15, 2008
Last sequence update:	May 30, 2006
Last modified:	November 3, 2009
This is version 27 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)