Reviewed, UniProtKB/Swiss-Prot Q1LTF0 (SYD_BAUCH)

Names and origin

Protein names

Recommended name:
    Aspartyl-tRNA synthetase
    EC=6.1.1.12
Alternative name(s):
    Aspartate--tRNA ligase
      Short name=AspRS

Gene names

Name:	aspS
Ordered Locus Names:	BCI_0315

Organism

Baumannia cicadellinicola subsp. Homalodisca coagulata [Complete proteome] [HAMAP]

Taxonomic identifier

374463 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Candidatus Baumannia

Protein attributes

Sequence length	589 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Catalytic activity	ATP + L-aspartate + tRNA(Asp) = AMP + diphosphate + L-aspartyl-tRNA(Asp). HAMAP MF_00044
Subunit structure	Homodimer By similarity.
Subcellular location	Cytoplasm By similarity.
Sequence similarities	Belongs to the class-II aminoacyl-tRNA synthetase family.

Ontologies

Keywords
Biological process	Protein biosynthesis
Cellular component	Cytoplasm
Ligand	ATP-binding Nucleotide-binding
Molecular function	Aminoacyl-tRNA synthetase Ligase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	aspartyl-tRNA aminoacylation Inferred from electronic annotation. Source: HAMAP
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	ATP binding Inferred from electronic annotation. Source: HAMAP aspartate-tRNA ligase activity Inferred from electronic annotation. Source: HAMAP nucleic acid binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 589	589	Aspartyl-tRNA synthetase HAMAP MF_00044		PRO_1000006639

Sequences

	Sequence		Length	Mass (Da)
	Q1LTF0-1 [UniParc]. Last modified May 30, 2006. Version 1. Checksum: 52E7422E511E9BF2	FASTA	589	67,501
	10 20 30 40 50 60 MRTIYCGQLN KSHLGQEVIL CGWVYRYRNL GRLIFIELSD REGRVQVVFD LTHPSIFSNA 70 80 90 100 110 120 AKLRNDFCIQ LHGIVRTRLD KQINYNITTG EIEVLATNLT ILNSSQPLPL DINFHNNEEQ 130 140 150 160 170 180 RLKFRYLDLR NPEMAQRLKL RAKITSLVRH FMEKKGFLDI ETPMLTKTTP EGARDYLVPS 190 200 210 220 230 240 RVHKGQFYAL PQSPQLFKQL LMISGFDRYY QIVKCFRDED LRADRQPEFT QIDVEASFIN 250 260 270 280 290 300 AEQICKIMED LVRHLWREIQ EVELENFQYM SYTAAMYRFG SDKPDLRNPI EIVDVVDLVK 310 320 330 340 350 360 NTTCTILADI AKDIKNRVVA LRVPNGAKLS LNDIKKYEKY IQTYGIKFII WMKVYQGKDG 370 380 390 400 410 420 VKTTQSSITK YLLPEDIMSI IERTGACDGD ILFFAAGNNN IINNVMGALR IKLGCDLKLN 430 440 450 460 470 480 RENSWAPLWI VDFPMFEKDD EGNLHAVHHP FTAPKNIDIP TLLQYPLKAK ANAYDMVING 490 500 510 520 530 540 YEVGSGSVRI HCAELQQTIF SILGMTRNEQ SSKFGFFIDA LKYGAPPHAG FAFGLDRLVM 550 560 570 580 LLTSTENIRD VIAFPKTTTA IDLMTEAPSI GNTIALKELS IEILDKNKI

References

[1]

"Metabolic complementarity and genomics of the dual bacterial symbiosis of sharpshooters." Wu D., Daugherty S.C., Van Aken S.E., Pai G.H., Watkins K.L., Khouri H., Tallon L.J., Zaborsky J.M., Dunbar H.E., Tran P.L., Moran N.A., Eisen J.A. PLoS Biol. 4:1079-1092(2006) [PubMed: 16729848] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBLGenBankDDBJ	CP000238 Genomic DNA. Translation: ABF14266.1.
RefSeq	YP_588764.1.
3D structure databases
ModBase	Search...
Genome annotation databases
GeneID	4056450.
GenomeReviews	Gene locus BCI_0315 in contig CP000238_GR.
KEGG	bci:BCI_0315.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	Q1LTF0.
OMA	Q1LTF0. VDRRRDH.
Family and domain databases
HAMAP	MF_00044. [Tree]
InterPro	IPR004364. aa-tRNA-synt_II. IPR018150. aa-tRNA-synt_II-like. IPR006195. aa-tRNA-synth_II_cons-reg. IPR002312. Asp-tRNA-synth_IIb. IPR004524. Asp-tRNA-synth_IIb_bac/mt. IPR018153. Asp-tRNA-synth_IIb_C_bac/mt. IPR004115. GAD. IPR012340. NA-bd_OB-fold. IPR004365. NA_bd_OB_tRNA-helicase. [Graphical view]
Gene3D	G3DSA:2.40.50.140. OB_NA_bd_sub. 1 hit.
PANTHER	PTHR22594. aa-tRNA-synt_II. 1 hit. PTHR22594:SF5. AspS_bac. 1 hit.
Pfam	PF02938. GAD. 1 hit. PF00152. tRNA-synt_2. 1 hit. PF01336. tRNA_anti. 1 hit. [Graphical view]
PRINTS	PR01042. TRNASYNTHASP.
TIGRFAMs	TIGR00459. aspS_bact. 1 hit.
PROSITE	PS50862. AA_TRNA_LIGASE_II. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

SYD_BAUCH

Accession

Primary (citable) accession number: Q1LTF0

Entry history

Integrated into UniProtKB/Swiss-Prot:	January 15, 2008
Last sequence update:	May 30, 2006
Last modified:	June 16, 2009
This is version 28 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)