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Protein

Translation initiation factor IF-1

Gene

infA

Organism
Baumannia cicadellinicola subsp. Homalodisca coagulata
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.UniRule annotation

GO - Molecular functioni

Keywordsi

Molecular functionInitiation factor, RNA-binding, rRNA-binding
Biological processProtein biosynthesis

Enzyme and pathway databases

BioCyciBCIC374463:G1G5N-324-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Translation initiation factor IF-1UniRule annotation
Gene namesi
Name:infAUniRule annotation
Ordered Locus Names:BCI_0322
OrganismiBaumannia cicadellinicola subsp. Homalodisca coagulata
Taxonomic identifieri374463 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaCandidatus Baumannia
Proteomesi
  • UP000002427 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002637651 – 72Translation initiation factor IF-1Add BLAST72

Interactioni

Subunit structurei

Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.UniRule annotation

Protein-protein interaction databases

STRINGi374463.BCI_0322

Structurei

3D structure databases

ProteinModelPortaliQ1LTE4
SMRiQ1LTE4
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini1 – 72S1-likeUniRule annotationAdd BLAST72

Sequence similaritiesi

Belongs to the IF-1 family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105K9U Bacteria
COG0361 LUCA
HOGENOMiHOG000221323
KOiK02518
OMAiECLRSAM
OrthoDBiPOG091H019C

Family and domain databases

CDDicd04451 S1_IF1, 1 hit
HAMAPiMF_00075 IF_1, 1 hit
InterProiView protein in InterPro
IPR012340 NA-bd_OB-fold
IPR006196 RNA-binding_domain_S1_IF1
IPR022967 S1_dom
IPR004368 TIF_IF1
PANTHERiPTHR33370 PTHR33370, 1 hit
PfamiView protein in Pfam
PF01176 eIF-1a, 1 hit
SMARTiView protein in SMART
SM00316 S1, 1 hit
SUPFAMiSSF50249 SSF50249, 1 hit
TIGRFAMsiTIGR00008 infA, 1 hit
PROSITEiView protein in PROSITE
PS50832 S1_IF1_TYPE, 1 hit

Sequencei

Sequence statusi: Complete.

Q1LTE4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTKEESIEIQ GIVLDTLANA VFRVELENGH IVTAHISGKM RKNYIRILTG
60 70
DKVTVELTPY DLKKGRITFR SR
Length:72
Mass (Da):8,216
Last modified:May 30, 2006 - v1
Checksum:iCBC94ED0C3A610D2
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000238 Genomic DNA Translation: ABF14160.1
RefSeqiWP_011520503.1, NC_007984.1

Genome annotation databases

EnsemblBacteriaiABF14160; ABF14160; BCI_0322
KEGGibci:BCI_0322

Similar proteinsi

Entry informationi

Entry nameiIF1_BAUCH
AccessioniPrimary (citable) accession number: Q1LTE4
Entry historyiIntegrated into UniProtKB/Swiss-Prot: December 12, 2006
Last sequence update: May 30, 2006
Last modified: March 28, 2018
This is version 72 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome