Reviewed, UniProtKB/Swiss-Prot Q1LTA9 (AROC_BAUCH)

Names and origin

Protein names

Recommended name:
    Chorismate synthase
    EC=4.2.3.5
Alternative name(s):
    5-enolpyruvylshikimate-3-phosphate phospholyase

Gene names

Name:	aroC
Ordered Locus Names:	BCI_0361

Organism

Baumannia cicadellinicola subsp. Homalodisca coagulata [Complete proteome] [HAMAP]

Taxonomic identifier

374463 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Candidatus Baumannia

Protein attributes

Sequence length	355 AA.
Sequence status	Complete.
Protein existence	Inferred from homology.

General annotation (Comments)

Catalytic activity	5-O-(1-carboxyvinyl)-3-phosphoshikimate = chorismate + phosphate. HAMAP MF_00300
Cofactor	Reduced flavin By similarity. HAMAP MF_00300
Pathway	Metabolic intermediate biosynthesis; chorismate biosynthesis; chorismate from D-erythrose 4-phosphate and phosphoenolpyruvate: step 7/7. HAMAP MF_00300
Subunit structure	Homotetramer By similarity. HAMAP MF_00300
Sequence similarities	Belongs to the chorismate synthase family.

Ontologies

Keywords
Biological process	Amino-acid biosynthesis Aromatic amino acid biosynthesis
Molecular function	Lyase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	aromatic amino acid family biosynthetic process Inferred from electronic annotation. Source: HAMAP
Molecular function	chorismate synthase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 355	355	Chorismate synthase HAMAP MF_00300		PRO_0000256272

Sequences

	Sequence		Length	Mass (Da)
	Q1LTA9-1 [UniParc]. Last modified May 30, 2006. Version 1. Checksum: 37034B73A82FBDA7	FASTA	355	38,678
	10 20 30 40 50 60 MGGNSIGNLF RVTTFGESHG KALGGIIDGV PPGMKLSEDD LQIDLNRRCP GKSLYITPRY 70 80 90 100 110 120 EHDKVYILSG IFEGVTTGTS IGLLVQNKDQ HSEDYQSIRD LYRPGHADYS YEKKYGMRDY 130 140 150 160 170 180 RGGGRSSARE TVIRVAAGAI AKKYLAYRCG IKIRGFIAQI GHIKCELKDW NQVEQNPFFC 190 200 210 220 230 240 PDIDCLEALD ILIRNLKKYG NSIGAKVTII AENVPAGLGE PVFDRLDADL AHALMSINAV 250 260 270 280 290 300 KGVEIGDGFA VISQLGNENR DEITSQGFLS NHAGGILGGI SSGQPVIAHI ALKPASSVKQ 310 320 330 340 350 PCNTVTRYGN EVEIITEGRH DICVGIRAVP IAEAMMAIVL MDHFLRNRAQ CSDVK

References

[1]

"Metabolic complementarity and genomics of the dual bacterial symbiosis of sharpshooters." Wu D., Daugherty S.C., Van Aken S.E., Pai G.H., Watkins K.L., Khouri H., Tallon L.J., Zaborsky J.M., Dunbar H.E., Tran P.L., Moran N.A., Eisen J.A. PLoS Biol. 4:1079-1092(2006) [PubMed: 16729848] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000238 Genomic DNA. Translation: ABF14196.1.
RefSeq	YP_588805.1.
3D structure databases
SMR	Q1LTA9. Positions 4-350.
ModBase	Search...
Protein-protein interaction databases
STRING	Q1LTA9.
Genome annotation databases
GeneID	4056493.
GenomeReviews	Gene locus BCI_0361 in contig CP000238_GR.
KEGG	bci:BCI_0361.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0082.
HOGENOM	HBG292336.
OMA	SRFTTQR.
PhylomeDB	Q1LTA9.
Family and domain databases
HAMAP	MF_00300_B. Chorismate_synth_B. [Tree]
InterPro	IPR000453. Chorismate_synth. IPR020541. Chorismate_synthase_CS. [Graphical view]
PANTHER	PTHR21085. Chorismate_synth. 1 hit.
Pfam	PF01264. Chorismate_synt. 1 hit. [Graphical view]
PIRSF	PIRSF001456. Chorismate_synth. 1 hit.
TIGRFAMs	TIGR00033. aroC. 1 hit.
PROSITE	PS00787. CHORISMATE_SYNTHASE_1. 1 hit. PS00788. CHORISMATE_SYNTHASE_2. 1 hit. PS00789. CHORISMATE_SYNTHASE_3. False negative. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

AROC_BAUCH

Accession

Primary (citable) accession number: Q1LTA9

Entry history

Integrated into UniProtKB/Swiss-Prot:	October 31, 2006
Last sequence update:	May 30, 2006
Last modified:	February 9, 2010
This is version 29 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)