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Protein

Methionyl-tRNA formyltransferase

Gene

fmt

Organism
Baumannia cicadellinicola subsp. Homalodisca coagulata
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.UniRule annotation

Catalytic activityi

10-formyltetrahydrofolate + L-methionyl-tRNA(fMet) = tetrahydrofolate + N-formylmethionyl-tRNA(fMet).UniRule annotation

GO - Molecular functioni

Keywordsi

Molecular functionTransferase
Biological processProtein biosynthesis

Enzyme and pathway databases

BioCyciBCIC374463:G1G5N-417-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Methionyl-tRNA formyltransferaseUniRule annotation (EC:2.1.2.9UniRule annotation)
Gene namesi
Name:fmtUniRule annotation
Ordered Locus Names:BCI_0415
OrganismiBaumannia cicadellinicola subsp. Homalodisca coagulata
Taxonomic identifieri374463 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaCandidatus Baumannia
Proteomesi
  • UP000002427 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10002038471 – 311Methionyl-tRNA formyltransferaseAdd BLAST311

Proteomic databases

PRIDEiQ1LT57

Interactioni

Protein-protein interaction databases

STRINGi374463.BCI_0415

Structurei

3D structure databases

ProteinModelPortaliQ1LT57
SMRiQ1LT57
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Regioni109 – 112Tetrahydrofolate (THF) bindingUniRule annotation4

Sequence similaritiesi

Belongs to the Fmt family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105CAE Bacteria
COG0223 LUCA
HOGENOMiHOG000261177
KOiK00604
OMAiLRIVFMG
OrthoDBiPOG091H01YM

Family and domain databases

Gene3Di3.10.25.10, 1 hit
HAMAPiMF_00182 Formyl_trans, 1 hit
InterProiView protein in InterPro
IPR005794 Fmt
IPR005793 Formyl_trans_C
IPR037022 Formyl_trans_C_sf
IPR002376 Formyl_transf_N
IPR036477 Formyl_transf_N_sf
IPR011034 Formyl_transferase-like_C_sf
IPR001555 GART_AS
PfamiView protein in Pfam
PF02911 Formyl_trans_C, 1 hit
PF00551 Formyl_trans_N, 1 hit
SUPFAMiSSF50486 SSF50486, 1 hit
SSF53328 SSF53328, 1 hit
TIGRFAMsiTIGR00460 fmt, 1 hit
PROSITEiView protein in PROSITE
PS00373 GART, 1 hit

Sequencei

Sequence statusi: Complete.

Q1LT57-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MRILFAGTPS FAAHYLSVLI NSPYKVVGVL TQPDRAAGRG NYLATSAVKQ
60 70 80 90 100
LAIKHNLPVF QPEYLHENNG KHIIEHISVD ILVVVAYGMI IPQDMLMFPK
110 120 130 140 150
LGGINIHGSL LPRWRGAAPI QRALWAGDIK TGITIIQMDD GLDTGPILYQ
160 170 180 190 200
VACKILPVDT STTLYAKLAK IGSTALLATL KQIITGSQVI EPQNNKFATY
210 220 230 240 250
ARKLNKKEAR IDWQLTANQL ERCIRAFNPW PISFFKIRDT IIKVWGAQID
260 270 280 290 300
DINYHHIPGT ILSVDPVGIK IATGKGAIII TQIQLAGTKQ MPVKDFLNSR
310
PTWFIPGNIL E
Length:311
Mass (Da):34,403
Last modified:May 30, 2006 - v1
Checksum:i46CAD1699D65E05A
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000238 Genomic DNA Translation: ABF13770.1
RefSeqiWP_011520590.1, NC_007984.1

Genome annotation databases

EnsemblBacteriaiABF13770; ABF13770; BCI_0415
KEGGibci:BCI_0415

Similar proteinsi

Entry informationi

Entry nameiFMT_BAUCH
AccessioniPrimary (citable) accession number: Q1LT57
Entry historyiIntegrated into UniProtKB/Swiss-Prot: September 22, 2009
Last sequence update: May 30, 2006
Last modified: May 23, 2018
This is version 80 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

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