Reviewed, UniProtKB/Swiss-Prot Q1LSP8 (SYK3_BAUCH)

Names and origin

Protein names

Recommended name:
    Putative lysyl-tRNA synthetase
    EC=6.1.1.6
Alternative name(s):
    Lysine--tRNA ligase
      Short name=LysRS
    GX

Gene names

Name:	poxA
Ordered Locus Names:	BCI_0588

Organism

Baumannia cicadellinicola subsp. Homalodisca coagulata [Complete proteome] [HAMAP]

Taxonomic identifier

374463 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Candidatus Baumannia

Protein attributes

Sequence length	327 AA.
Sequence status	Complete.
Protein existence	Inferred from homology.

General annotation (Comments)

Function	Could be a lysyl-tRNA synthetase. HAMAP MF_00174
Catalytic activity	ATP + L-lysine + tRNA(Lys) = AMP + diphosphate + L-lysyl-tRNA(Lys). HAMAP MF_00174
Sequence similarities	Belongs to the class-II aminoacyl-tRNA synthetase family.

Ontologies

Keywords
Biological process	Protein biosynthesis
Ligand	ATP-binding Nucleotide-binding
Molecular function	Aminoacyl-tRNA synthetase Ligase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	lysyl-tRNA aminoacylation Inferred from electronic annotation. Source: HAMAP
Cellular component	cytoplasm Inferred from electronic annotation. Source: InterPro
Molecular function	ATP binding Inferred from electronic annotation. Source: HAMAP lysine-tRNA ligase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 327	327	Putative lysyl-tRNA synthetase HAMAP MF_00174		PRO_1000023618

Sequences

	Sequence		Length	Mass (Da)
	Q1LSP8-1 [UniParc]. Last modified May 30, 2006. Version 1. Checksum: AFBCEC5E3E18E657	FASTA	327	37,877
	10 20 30 40 50 60 MNKLISWKPR ASIHNLFIRA KIINNIRIFF INRGLLEVET PVMSHTTVPD IYLFPFQTNL 70 80 90 100 110 120 YFLEKVPEKG VPMYLITSPE YHMKRLLAAG SGPIFQICHS FRNQEYGNYH NPEFTLLEWY 130 140 150 160 170 180 RPYYNMVDIM DEVNIFLQTI IHCDSAEMLS YQQVFRLHVG IDPLLAELDE LNQVLVKFNL 190 200 210 220 230 240 SSTISLYNDR DKLLDFLFLM LVRPHLGNNK PVFIYNFPAS QSLLAELNSD DHRVAERFEV 250 260 270 280 290 300 YFHGIELANG SRELTDADLQ RERFMQENNK QVAMNRPPRL IDEQLLAALE CGLPSCSGVA 310 320 LGIDRLLMLT LKAKHISEVM AFSVTDA

References

[1]

"Metabolic complementarity and genomics of the dual bacterial symbiosis of sharpshooters." Wu D., Daugherty S.C., Van Aken S.E., Pai G.H., Watkins K.L., Khouri H., Tallon L.J., Zaborsky J.M., Dunbar H.E., Tran P.L., Moran N.A., Eisen J.A. PLoS Biol. 4:1079-1092(2006) [PubMed: 16729848] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000238 Genomic DNA. Translation: ABF13878.1.
RefSeq	YP_589016.1.
3D structure databases
SMR	Q1LSP8. Positions 14-324.
ModBase	Search...
Protein-protein interaction databases
STRING	Q1LSP8.
Genome annotation databases
GeneID	4056657.
GenomeReviews	Gene locus BCI_0588 in contig CP000238_GR.
KEGG	bci:BCI_0588.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG2269.
HOGENOM	HBG631383.
OMA	PGNEAHL.
PhylomeDB	Q1LSP8.
Family and domain databases
HAMAP	MF_00174. Put_Lys_tRNA_synth. [Tree]
InterPro	IPR004364. aa-tRNA-synt_II. IPR018150. aa-tRNA-synt_II-like. IPR006195. aa-tRNA-synth_II_cons-dom. IPR004525. Lys-tRNA-synth-rel. [Graphical view]
PANTHER	PTHR22594. aa-tRNA-synt_II. 1 hit.
Pfam	PF00152. tRNA-synt_2. 1 hit. [Graphical view]
TIGRFAMs	TIGR00462. genX. 1 hit.
PROSITE	PS50862. AA_TRNA_LIGASE_II. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

SYK3_BAUCH

Accession

Primary (citable) accession number: Q1LSP8

Entry history

Integrated into UniProtKB/Swiss-Prot:	January 15, 2008
Last sequence update:	May 30, 2006
Last modified:	February 9, 2010
This is version 31 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)