Reviewed,
UniProtKB/Swiss-Prot Q1LSL2 (PNP_BAUCH)
Last modified
June 16, 2009.
Version 24.
History...
Clusters with 100%,
90%,
50% identity |
Documents (1) |
Third-party data |
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Names and origin
| Protein names | Recommended name: Polyribonucleotide nucleotidyltransferase EC=2.7.7.8 Alternative name(s): Polynucleotide phosphorylase Short name=PNPase | ||||
| Gene names |
| ||||
| Organism | Baumannia cicadellinicola subsp. Homalodisca coagulata [Complete proteome] [HAMAP] | ||||
| Taxonomic identifier | 374463 [NCBI] | ||||
| Taxonomic lineage | Bacteria › Proteobacteria › Gammaproteobacteria › Candidatus Baumannia |
Protein attributes
| Sequence length | 697 AA. |
| Sequence status | Complete. |
| Sequence processing | The displayed sequence is not processed. |
| Protein existence | Inferred from homology. |
General annotation (Comments)
| Function | Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction By similarity. |
| Catalytic activity | RNA(n+1) + phosphate = RNA(n) + a nucleoside diphosphate. HAMAP MF_01595 |
| Subunit structure | Homotrimer. Organized into a structure (processome or RNA degradosome) containing a number of RNA-processing enzymes By similarity. |
| Subcellular location | Cytoplasm By similarity. |
| Sequence similarities | Belongs to the polyribonucleotide nucleotidyltransferase family. Contains 1 KH domain. Contains 1 S1 motif domain. |
Ontologies
| Keywords | |
|---|---|
| Cellular component | Cytoplasm |
| Ligand | RNA-binding |
| Molecular function | Nucleotidyltransferase Transferase |
| Technical term | Complete proteome |
| Gene Ontology (GO) | |
| Biological process | RNA processing Inferred from electronic annotation. Source: InterPro mRNA catabolic processInferred from electronic annotation. Source: HAMAP |
| Cellular component | cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell |
| Molecular function | 3'-5'-exoribonuclease activity Inferred from electronic annotation. Source: InterPro RNA bindingInferred from electronic annotation. Source: UniProtKB-KW polyribonucleotide nucleotidyltransferase activityInferred from electronic annotation. Source: HAMAP |
| Complete GO annotation... | |
Sequence annotation (Features)
| Feature key | Position(s) | Length | Description | Graphical view | Feature identifier | ||||
Molecule processing | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Chain | 1 – 697 | 697 | Polyribonucleotide nucleotidyltransferase HAMAP MF_01595 | PRO_0000329529 | |||||
Regions | |||||||||
| Domain | 553 – 612 | 60 | KH | ||||||
| Domain | 622 – 690 | 69 | S1 motif | ||||||
Sequences
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References
| [1] | "Metabolic complementarity and genomics of the dual bacterial symbiosis of sharpshooters." Wu D., Daugherty S.C., Van Aken S.E., Pai G.H., Watkins K.L., Khouri H., Tallon L.J., Zaborsky J.M., Dunbar H.E., Tran P.L., Moran N.A., Eisen J.A. PLoS Biol. 4:1079-1092(2006) [PubMed: 16729848] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. |
Cross-references
Sequence databases | |
|---|---|
| CP000238 Genomic DNA. Translation: ABF13852.1. | |
| RefSeq | YP_589052.1. |
3D structure databases | |
| SMR | Q1LSL2. Positions 617-691. |
| ModBase | Search... |
Genome annotation databases | |
| GeneID | 4056300. |
| GenomeReviews | Gene locus BCI_0627 in contig CP000238_GR. |
| KEGG | bci:BCI_0627. |
Organism-specific databases | |
| CMR | Search... |
Phylogenomic databases | |
| HOGENOM | Q1LSL2. |
| OMA | Q1LSL2. GHGNLAK. |
Family and domain databases | |
| HAMAP | MF_01595. [Tree] |
| InterPro | IPR001247. ExoRNase_PH_dom1. IPR015847. ExoRNase_PH_dom2. IPR004087. KH. IPR004088. KH_type_1. IPR018111. KH_type_1_subgr. IPR012340. NA-bd_OB-fold. IPR012162. PNPase. IPR015848. PNPase_PH_RNA-bd_bac/org-type. IPR003029. Rbsml_prot_S1_RNA-bd_dom. [Graphical view] |
| Gene3D | G3DSA:2.40.50.140. OB_NA_bd_sub. 1 hit. G3DSA:1.10.10.400. PNPase_PH_RNA-bd_bac/org-type. 1 hit. |
| PANTHER | PTHR11252. PNPase. 1 hit. |
| Pfam | PF00013. KH_1. 1 hit. PF03726. PNPase. 1 hit. PF01138. RNase_PH. 2 hits. PF03725. RNase_PH_C. 2 hits. PF00575. S1. 1 hit. [Graphical view] |
| PIRSF | PIRSF005499. PNPase. 1 hit. |
| SMART | SM00322. KH. 1 hit. [Graphical view] |
| TIGRFAMs | TIGR03591. Polynuc_phos. 1 hit. |
| PROSITE | PS50084. KH_TYPE_1. 1 hit. PS50126. S1. 1 hit. [Graphical view] |
| ProtoNet | Search... |
Entry information
| Entry name | PNP_BAUCH | ||||||||
| Accession | Primary (citable) accession number: Q1LSL2 | ||||||||
| Entry history |
| ||||||||
| Entry status | Reviewed (UniProtKB/Swiss-Prot) | ||||||||
| Annotation project | HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes) | ||||||||

Clusters with


