Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Basket 0
(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Q1LNE5

- LPXB_RALME

UniProt

Q1LNE5 - LPXB_RALME

Protein

Lipid-A-disaccharide synthase

Gene

lpxB

Organism
Ralstonia metallidurans (strain CH34 / ATCC 43123 / DSM 2839)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
    • BLAST
    • Align
    • Format
    • Add to basket
    • History
      Entry version 51 (01 Oct 2014)
      Sequence version 1 (30 May 2006)
      Previous versions | rss
    • Help video
    • Feedback
    • Comment

    Functioni

    Condensation of UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.UniRule annotation

    Catalytic activityi

    UDP-2,3-bis(3-hydroxytetradecanoyl)glucosamine + 2,3-bis(3-hydroxytetradecanoyl)-beta-D-glucosaminyl 1-phosphate = UDP + 2,3-bis(3-hydroxytetradecanoyl)-D-glucosaminyl-1,6-beta-D-2,3-bis(3-hydroxytetradecanoyl)-beta-D-glucosaminyl 1-phosphate.UniRule annotation

    Pathwayi

    GO - Molecular functioni

    1. lipid-A-disaccharide synthase activity Source: UniProtKB-EC

    GO - Biological processi

    1. lipid A biosynthetic process Source: UniProtKB-KW

    Keywords - Molecular functioni

    Glycosyltransferase, Transferase

    Keywords - Biological processi

    Lipid A biosynthesis, Lipid biosynthesis, Lipid metabolism

    Enzyme and pathway databases

    BioCyciCMET266264:GJ5G-1509-MONOMER.
    UniPathwayiUPA00359; UER00481.

    Protein family/group databases

    CAZyiGT19. Glycosyltransferase Family 19.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Lipid-A-disaccharide synthaseUniRule annotation (EC:2.4.1.182UniRule annotation)
    Gene namesi
    Name:lpxBUniRule annotation
    Ordered Locus Names:Rmet_1448
    OrganismiRalstonia metallidurans (strain CH34 / ATCC 43123 / DSM 2839)
    Taxonomic identifieri266264 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaBetaproteobacteriaBurkholderialesBurkholderiaceaeCupriavidus
    ProteomesiUP000002429: Chromosome

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 401401Lipid-A-disaccharide synthasePRO_0000255212Add
    BLAST

    Interactioni

    Protein-protein interaction databases

    STRINGi266264.Rmet_1448.

    Structurei

    3D structure databases

    ProteinModelPortaliQ1LNE5.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the LpxB family.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG0763.
    HOGENOMiHOG000018003.
    KOiK00748.
    OMAiVSPITYR.
    OrthoDBiEOG6FBWZR.

    Family and domain databases

    HAMAPiMF_00392. LpxB.
    InterProiIPR003835. Glyco_trans_19.
    [Graphical view]
    PfamiPF02684. LpxB. 1 hit.
    [Graphical view]
    TIGRFAMsiTIGR00215. lpxB. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    Q1LNE5-1 [UniParc]FASTAAdd to Basket

    « Hide

    MVDTVQAVLP ADAGANGNKR GSIAMVAGEA SGDLLASLLL EGLRARLGES    50
    VDYAGIGGHR MMAQGFVSHW PMETLSVNGY VEVLGSLREI LATRREIREQ 100
    LLARPPLCFI GVDAPDFNFG LEVPLRRAGI PVVHFVSPSI WAWRGGRIRT 150
    IARAVDHILC LFPFEPEIYA KAGIPATYVG HPLADVIPMV PDVAGARAKL 200
    ALPEGKRIVA VLPGSRQSEV RNLGATFFAA MDRMHRMDGN LAFVLPVASA 250
    PLREIVAGLH AQYPDIDLTV VDGQSHLAME SADVVLLASG TATLEAALYK 300
    KPMVISYKVP WLTAQIMKRQ GYLPYVGLPN ILSGRFVVPE LLQDDATPEA 350
    LARETLLQLN DEGNIAFLRQ HFTTMHETLK RDTAKLAAGV VVDLMRSRGV 400
    V 401
    Length:401
    Mass (Da):43,417
    Last modified:May 30, 2006 - v1
    Checksum:iC02EB9CE4BB11AAB
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000352 Genomic DNA. Translation: ABF08331.1.
    RefSeqiWP_011516197.1. NC_007973.1.
    YP_583600.1. NC_007973.1.

    Genome annotation databases

    EnsemblBacteriaiABF08331; ABF08331; Rmet_1448.
    GeneIDi4038251.
    KEGGirme:Rmet_1448.
    PATRICi20287510. VBIRalMet4734_1857.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000352 Genomic DNA. Translation: ABF08331.1 .
    RefSeqi WP_011516197.1. NC_007973.1.
    YP_583600.1. NC_007973.1.

    3D structure databases

    ProteinModelPortali Q1LNE5.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 266264.Rmet_1448.

    Protein family/group databases

    CAZyi GT19. Glycosyltransferase Family 19.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai ABF08331 ; ABF08331 ; Rmet_1448 .
    GeneIDi 4038251.
    KEGGi rme:Rmet_1448.
    PATRICi 20287510. VBIRalMet4734_1857.

    Phylogenomic databases

    eggNOGi COG0763.
    HOGENOMi HOG000018003.
    KOi K00748.
    OMAi VSPITYR.
    OrthoDBi EOG6FBWZR.

    Enzyme and pathway databases

    UniPathwayi UPA00359 ; UER00481 .
    BioCyci CMET266264:GJ5G-1509-MONOMER.

    Family and domain databases

    HAMAPi MF_00392. LpxB.
    InterProi IPR003835. Glyco_trans_19.
    [Graphical view ]
    Pfami PF02684. LpxB. 1 hit.
    [Graphical view ]
    TIGRFAMsi TIGR00215. lpxB. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: CH34 / ATCC 43123 / DSM 2839.

    Entry informationi

    Entry nameiLPXB_RALME
    AccessioniPrimary (citable) accession number: Q1LNE5
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: October 31, 2006
    Last sequence update: May 30, 2006
    Last modified: October 1, 2014
    This is version 51 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. PATHWAY comments
      Index of metabolic and biosynthesis pathways
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3