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Protein

Glutamate decarboxylase

Gene

gadB

Organism
Ralstonia metallidurans (strain CH34 / ATCC 43123 / DSM 2839)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

L-glutamate = 4-aminobutanoate + CO2.UniRule annotation

Cofactori

pyridoxal 5'-phosphateUniRule annotation

GO - Molecular functioni

  1. glutamate decarboxylase activity Source: UniProtKB-EC
  2. pyridoxal phosphate binding Source: InterPro

GO - Biological processi

  1. glutamate metabolic process Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

DecarboxylaseUniRule annotation, Lyase

Keywords - Ligandi

Pyridoxal phosphateUniRule annotation

Enzyme and pathway databases

BioCyciCMET266264:GJ5G-1853-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Glutamate decarboxylaseUniRule annotation (EC:4.1.1.15UniRule annotation)
Gene namesi
Name:gadBImported
Ordered Locus Names:Rmet_1766Imported
OrganismiRalstonia metallidurans (strain CH34 / ATCC 43123 / DSM 2839)Imported
Taxonomic identifieri266264 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaBetaproteobacteriaBurkholderialesBurkholderiaceaeCupriavidus
ProteomesiUP000002429: Chromosome

Interactioni

Protein-protein interaction databases

STRINGi266264.Rmet_1766.

Structurei

3D structure databases

ProteinModelPortaliQ1LMI1.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the group II decarboxylase family.UniRule annotation

Phylogenomic databases

eggNOGiCOG0076.
HOGENOMiHOG000070228.
KOiK01580.
OMAiFVGTWMD.
OrthoDBiEOG6TFCPW.

Family and domain databases

Gene3Di3.40.640.10. 1 hit.
InterProiIPR010107. Glutamate_decarboxylase.
IPR002129. PyrdxlP-dep_de-COase.
IPR015424. PyrdxlP-dep_Trfase.
IPR015421. PyrdxlP-dep_Trfase_major_sub1.
[Graphical view]
PANTHERiPTHR11999:SF1. PTHR11999:SF1. 1 hit.
PfamiPF00282. Pyridoxal_deC. 1 hit.
[Graphical view]
SUPFAMiSSF53383. SSF53383. 1 hit.
TIGRFAMsiTIGR01788. Glu-decarb-GAD. 1 hit.

Sequencei

Sequence statusi: Complete.

Q1LMI1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSDMQEHKVT PYDQFNYEVP ENVFPREGIS ANAAAAIVIS DEWTDTNPML
60 70 80 90 100
NMSSFVTTFA EPEAREVAAR NIFKNYIDHD MYPRLFAMEG RMVRWLHELW
110 120 130 140 150
NGPKGVEPYG TCTVGSSEAC MLGGLAHKWN WRQRRQAEGK DATRPNMVTG
160 170 180 190 200
GNVQIVWKKF LRYFDVEPRI VPLKPGNYCL TAEDLDKYVD ENTICVVAIA
210 220 230 240 250
GQTFTGEDDD IQGIHDWLDA YEKRTGISIP MHIDGASGGF VNPFLYPDYK
260 270 280 290 300
WDFRLPRVQS INASGHKYGL TPPGLGWVVF RERKIFNEEL VFYVNYLGGE
310 320 330 340 350
MPTATLNFSR NAFQVAVQYY QFLRLGFDGY KRVMQHTLDN AIFLRQQLVD
360 370 380 390 400
SGYFDIMNTT QRIPVVAVTL NKKYKNFNEF DVSNKVREKG WVLSAYTMPP
410 420 430 440 450
NAESVTSLRV VVRPHVNHNV AQLLANDIIN ACKFLEANGG NAKPPALHKH
460
AEAQSTSLKC
Length:460
Mass (Da):52,338
Last modified:May 30, 2006 - v1
Checksum:i65F6E8AD4E912697
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000352 Genomic DNA. Translation: ABF08645.1.
RefSeqiYP_583914.1. NC_007973.1.

Genome annotation databases

EnsemblBacteriaiABF08645; ABF08645; Rmet_1766.
GeneIDi4038568.
KEGGirme:Rmet_1766.
PATRICi20288152. VBIRalMet4734_2178.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000352 Genomic DNA. Translation: ABF08645.1.
RefSeqiYP_583914.1. NC_007973.1.

3D structure databases

ProteinModelPortaliQ1LMI1.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi266264.Rmet_1766.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiABF08645; ABF08645; Rmet_1766.
GeneIDi4038568.
KEGGirme:Rmet_1766.
PATRICi20288152. VBIRalMet4734_2178.

Phylogenomic databases

eggNOGiCOG0076.
HOGENOMiHOG000070228.
KOiK01580.
OMAiFVGTWMD.
OrthoDBiEOG6TFCPW.

Enzyme and pathway databases

BioCyciCMET266264:GJ5G-1853-MONOMER.

Family and domain databases

Gene3Di3.40.640.10. 1 hit.
InterProiIPR010107. Glutamate_decarboxylase.
IPR002129. PyrdxlP-dep_de-COase.
IPR015424. PyrdxlP-dep_Trfase.
IPR015421. PyrdxlP-dep_Trfase_major_sub1.
[Graphical view]
PANTHERiPTHR11999:SF1. PTHR11999:SF1. 1 hit.
PfamiPF00282. Pyridoxal_deC. 1 hit.
[Graphical view]
SUPFAMiSSF53383. SSF53383. 1 hit.
TIGRFAMsiTIGR01788. Glu-decarb-GAD. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: CH34 / ATCC 43123 / DSM 2839Imported.

Entry informationi

Entry nameiQ1LMI1_RALME
AccessioniPrimary (citable) accession number: Q1LMI1
Entry historyi
Integrated into UniProtKB/TrEMBL: May 30, 2006
Last sequence update: May 30, 2006
Last modified: February 4, 2015
This is version 65 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.