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Q1LM68 (G6PI_RALME) Reviewed, UniProtKB/Swiss-Prot

Last modified June 11, 2014. Version 51. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Glucose-6-phosphate isomerase

Short name=GPI
EC=5.3.1.9
Alternative name(s):
Phosphoglucose isomerase
Short name=PGI
Phosphohexose isomerase
Short name=PHI
Gene names
Name:pgi
Ordered Locus Names:Rmet_1879
OrganismRalstonia metallidurans (strain CH34 / ATCC 43123 / DSM 2839) [Complete proteome] [HAMAP]
Taxonomic identifier266264 [NCBI]
Taxonomic lineageBacteriaProteobacteriaBetaproteobacteriaBurkholderialesBurkholderiaceaeCupriavidus

Protein attributes

Sequence length541 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

D-glucose 6-phosphate = D-fructose 6-phosphate. HAMAP-Rule MF_00473

Pathway

Carbohydrate degradation; glycolysis; D-glyceraldehyde 3-phosphate and glycerone phosphate from D-glucose: step 2/4. HAMAP-Rule MF_00473

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00473.

Sequence similarities

Belongs to the GPI family.

Ontologies

Keywords
   Biological processGluconeogenesis
Glycolysis
   Cellular componentCytoplasm
   Molecular functionIsomerase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processgluconeogenesis

Inferred from electronic annotation. Source: UniProtKB-HAMAP

glycolytic process

Inferred from electronic annotation. Source: UniProtKB-HAMAP

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionglucose-6-phosphate isomerase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 541541Glucose-6-phosphate isomerase HAMAP-Rule MF_00473
PRO_0000252634

Sites

Active site3541Proton donor By similarity
Active site3851 By similarity
Active site5051 By similarity

Sequences

Sequence LengthMass (Da)Tools
Q1LM68 [UniParc].

Last modified May 30, 2006. Version 1.
Checksum: C0CA28A2D2DA80EF

FASTA54159,349
        10         20         30         40         50         60 
MPTDLQAWNA LRQHHDVVRE TPMQQWFAEA GAAQRVDAFS LEASGLYLDY SKNRITGETL 

        70         80         90        100        110        120 
ALLMKLAEEA GVPARRDAMF AGEHINATED RAALHVALRA LPDAPFKVDG ASVMPAIHDV 

       130        140        150        160        170        180 
LRRMREFAGR VRSGVWTGST GQGITDIVNI GIGGSDLGPR MVCRALAHLA DPRGPRVHFV 

       190        200        210        220        230        240 
SNVDGTELAE TLQRLDPART LAIVCSKTFT TLETMANACS MRDWFLRHGV AENQLARHFV 

       250        260        270        280        290        300 
AVSTNRDAVV DFGIDPNNMF EFWDWIGGRF SLWSSVGLSI ALAVGFDAFE DLLLGARAMD 

       310        320        330        340        350        360 
DHFRTAPLAQ NMPVVMAMLG IWYRNFHDMP TSCMAPYSTS LELFPAFLQQ LEMESNGKSV 

       370        380        390        400        410        420 
QLDGRPVDAD TAPVVWGTAG TNGQHAYFQM IHQGSQIVPV DFVAPLVPPR ELPGHHVKLL 

       430        440        450        460        470        480 
ANCFAQAEAL MRGRSAEELQ AAGVDAARIP HMVFEGNRPS NMLLMENLTP HVLGALIALY 

       490        500        510        520        530        540 
EHRTFVQGIV WNINSFDQWG VELGKILARP IEAELSGNAT EAHDASTAAL IARARRSLAR 


S 

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References

[1]"Complete sequence of the chromosome of Ralstonia metallidurans CH34."
US DOE Joint Genome Institute
Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Martinez M., Goltsman E., Pitluck S., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N. expand/collapse author list , Kim E., Mergeay M., Benotmane M.A., Vallaeys T., Michaux A., Monchy S., Dunn J., McCorkle S., Taghavi S., van der Lelie D., Richardson P.
Submitted (APR-2006) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: CH34 / ATCC 43123 / DSM 2839.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP000352 Genomic DNA. Translation: ABF08758.1.
RefSeqYP_584027.1. NC_007973.1.

3D structure databases

ProteinModelPortalQ1LM68.
SMRQ1LM68. Positions 3-536.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING266264.Rmet_1879.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaABF08758; ABF08758; Rmet_1879.
GeneID4038681.
KEGGrme:Rmet_1879.
PATRIC20288380. VBIRalMet4734_2292.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0166.
HOGENOMHOG000261370.
KOK01810.
OMANCHFVAN.
OrthoDBEOG64R61J.

Enzyme and pathway databases

BioCycCMET266264:GJ5G-1973-MONOMER.
UniPathwayUPA00109; UER00181.

Family and domain databases

Gene3D1.10.1390.10. 1 hit.
HAMAPMF_00473. G6P_isomerase.
InterProIPR001672. G6P_Isomerase.
IPR023096. G6P_Isomerase_C.
IPR018189. Phosphoglucose_isomerase_CS.
[Graphical view]
PANTHERPTHR11469. PTHR11469. 1 hit.
PfamPF00342. PGI. 1 hit.
[Graphical view]
PRINTSPR00662. G6PISOMERASE.
PROSITEPS00765. P_GLUCOSE_ISOMERASE_1. 1 hit.
PS00174. P_GLUCOSE_ISOMERASE_2. 1 hit.
PS51463. P_GLUCOSE_ISOMERASE_3. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameG6PI_RALME
AccessionPrimary (citable) accession number: Q1LM68
Entry history
Integrated into UniProtKB/Swiss-Prot: October 17, 2006
Last sequence update: May 30, 2006
Last modified: June 11, 2014
This is version 51 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways