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Protein

Glucose-6-phosphate isomerase

Gene

pgi

Organism
Ralstonia metallidurans (strain CH34 / ATCC 43123 / DSM 2839)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

D-glucose 6-phosphate = D-fructose 6-phosphate.UniRule annotation

Pathway:iglycolysis

This protein is involved in step 2 of the subpathway that synthesizes D-glyceraldehyde 3-phosphate and glycerone phosphate from D-glucose.UniRule annotation
Proteins known to be involved in the 4 steps of the subpathway in this organism are:
  1. no protein annotated in this organism
  2. Glucose-6-phosphate isomerase (pgi)
  3. no protein annotated in this organism
  4. no protein annotated in this organism
This subpathway is part of the pathway glycolysis, which is itself part of Carbohydrate degradation.
View all proteins of this organism that are known to be involved in the subpathway that synthesizes D-glyceraldehyde 3-phosphate and glycerone phosphate from D-glucose, the pathway glycolysis and in Carbohydrate degradation.

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei354 – 3541Proton donorUniRule annotation
Active sitei385 – 3851UniRule annotation
Active sitei505 – 5051UniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Isomerase

Keywords - Biological processi

Gluconeogenesis, Glycolysis

Enzyme and pathway databases

BioCyciCMET266264:GJ5G-1973-MONOMER.
UniPathwayiUPA00109; UER00181.

Names & Taxonomyi

Protein namesi
Recommended name:
Glucose-6-phosphate isomeraseUniRule annotation (EC:5.3.1.9UniRule annotation)
Short name:
GPIUniRule annotation
Alternative name(s):
Phosphoglucose isomeraseUniRule annotation
Short name:
PGIUniRule annotation
Phosphohexose isomeraseUniRule annotation
Short name:
PHIUniRule annotation
Gene namesi
Name:pgiUniRule annotation
Ordered Locus Names:Rmet_1879
OrganismiRalstonia metallidurans (strain CH34 / ATCC 43123 / DSM 2839)
Taxonomic identifieri266264 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaBetaproteobacteriaBurkholderialesBurkholderiaceaeCupriavidus
ProteomesiUP000002429 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 541541Glucose-6-phosphate isomerasePRO_0000252634Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi266264.Rmet_1879.

Structurei

3D structure databases

ProteinModelPortaliQ1LM68.
SMRiQ1LM68. Positions 3-536.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the GPI family.UniRule annotation

Phylogenomic databases

eggNOGiCOG0166.
HOGENOMiHOG000261370.
KOiK01810.
OMAiCETQAML.
OrthoDBiEOG64R61J.

Family and domain databases

Gene3Di1.10.1390.10. 1 hit.
HAMAPiMF_00473. G6P_isomerase.
InterProiIPR001672. G6P_Isomerase.
IPR023096. G6P_Isomerase_C.
IPR018189. Phosphoglucose_isomerase_CS.
[Graphical view]
PANTHERiPTHR11469. PTHR11469. 1 hit.
PfamiPF00342. PGI. 1 hit.
[Graphical view]
PRINTSiPR00662. G6PISOMERASE.
PROSITEiPS00765. P_GLUCOSE_ISOMERASE_1. 1 hit.
PS00174. P_GLUCOSE_ISOMERASE_2. 1 hit.
PS51463. P_GLUCOSE_ISOMERASE_3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q1LM68-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MPTDLQAWNA LRQHHDVVRE TPMQQWFAEA GAAQRVDAFS LEASGLYLDY
60 70 80 90 100
SKNRITGETL ALLMKLAEEA GVPARRDAMF AGEHINATED RAALHVALRA
110 120 130 140 150
LPDAPFKVDG ASVMPAIHDV LRRMREFAGR VRSGVWTGST GQGITDIVNI
160 170 180 190 200
GIGGSDLGPR MVCRALAHLA DPRGPRVHFV SNVDGTELAE TLQRLDPART
210 220 230 240 250
LAIVCSKTFT TLETMANACS MRDWFLRHGV AENQLARHFV AVSTNRDAVV
260 270 280 290 300
DFGIDPNNMF EFWDWIGGRF SLWSSVGLSI ALAVGFDAFE DLLLGARAMD
310 320 330 340 350
DHFRTAPLAQ NMPVVMAMLG IWYRNFHDMP TSCMAPYSTS LELFPAFLQQ
360 370 380 390 400
LEMESNGKSV QLDGRPVDAD TAPVVWGTAG TNGQHAYFQM IHQGSQIVPV
410 420 430 440 450
DFVAPLVPPR ELPGHHVKLL ANCFAQAEAL MRGRSAEELQ AAGVDAARIP
460 470 480 490 500
HMVFEGNRPS NMLLMENLTP HVLGALIALY EHRTFVQGIV WNINSFDQWG
510 520 530 540
VELGKILARP IEAELSGNAT EAHDASTAAL IARARRSLAR S
Length:541
Mass (Da):59,349
Last modified:May 30, 2006 - v1
Checksum:iC0CA28A2D2DA80EF
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000352 Genomic DNA. Translation: ABF08758.1.
RefSeqiWP_011516605.1. NC_007973.1.

Genome annotation databases

EnsemblBacteriaiABF08758; ABF08758; Rmet_1879.
GeneIDi24149087.
KEGGirme:Rmet_1879.
PATRICi20288380. VBIRalMet4734_2292.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000352 Genomic DNA. Translation: ABF08758.1.
RefSeqiWP_011516605.1. NC_007973.1.

3D structure databases

ProteinModelPortaliQ1LM68.
SMRiQ1LM68. Positions 3-536.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi266264.Rmet_1879.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiABF08758; ABF08758; Rmet_1879.
GeneIDi24149087.
KEGGirme:Rmet_1879.
PATRICi20288380. VBIRalMet4734_2292.

Phylogenomic databases

eggNOGiCOG0166.
HOGENOMiHOG000261370.
KOiK01810.
OMAiCETQAML.
OrthoDBiEOG64R61J.

Enzyme and pathway databases

UniPathwayiUPA00109; UER00181.
BioCyciCMET266264:GJ5G-1973-MONOMER.

Family and domain databases

Gene3Di1.10.1390.10. 1 hit.
HAMAPiMF_00473. G6P_isomerase.
InterProiIPR001672. G6P_Isomerase.
IPR023096. G6P_Isomerase_C.
IPR018189. Phosphoglucose_isomerase_CS.
[Graphical view]
PANTHERiPTHR11469. PTHR11469. 1 hit.
PfamiPF00342. PGI. 1 hit.
[Graphical view]
PRINTSiPR00662. G6PISOMERASE.
PROSITEiPS00765. P_GLUCOSE_ISOMERASE_1. 1 hit.
PS00174. P_GLUCOSE_ISOMERASE_2. 1 hit.
PS51463. P_GLUCOSE_ISOMERASE_3. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: CH34 / ATCC 43123 / DSM 2839.

Entry informationi

Entry nameiG6PI_RALME
AccessioniPrimary (citable) accession number: Q1LM68
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 17, 2006
Last sequence update: May 30, 2006
Last modified: July 22, 2015
This is version 60 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.