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Q1LKJ7 (FENR2_RALME) Reviewed, UniProtKB/Swiss-Prot

Last modified January 25, 2012. Version 44. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Ferredoxin--NADP reductase 2
Short name=FNR 2
Short name=Fd-NADP+ reductase 2
EC=1.18.1.2
Gene names
Ordered Locus Names:Rmet_2452
OrganismRalstonia metallidurans (strain CH34 / ATCC 43123 / DSM 2839) [Complete proteome] [HAMAP]
Taxonomic identifier266264 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Betaproteobacteria › Burkholderiales › Burkholderiaceae › Cupriavidus

Protein attributes

Sequence length367 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

2 reduced ferredoxin + NADP+ + H+ = 2 oxidized ferredoxin + NADPH. HAMAP MF_01685

Cofactor

Binds 1 FAD per subunit By similarity. HAMAP MF_01685

Subunit structure

Homodimer By similarity. HAMAP MF_01685

Sequence similarities

Belongs to the ferredoxin--NADP reductase type 2 family.

Ontologies

Keywords
   LigandFAD
Flavoprotein
NADP
   Molecular functionOxidoreductase
   Technical termComplete proteome
Gene Ontology (GO)
   Molecular functionferredoxin-NADP+ reductase activity

Inferred from electronic annotation. Source: EC

flavin adenine dinucleotide binding

Inferred from electronic annotation. Source: InterPro

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 367367Ferredoxin--NADP reductase 2 HAMAP MF_01685
PRO_0000364908

Sites

Binding site561FAD By similarity
Binding site641FAD By similarity
Binding site691FAD By similarity
Binding site1091FAD; via amide nitrogen and carbonyl oxygen By similarity
Binding site1441FAD; via amide nitrogen By similarity
Binding site3091FAD By similarity
Binding site3501FAD By similarity

Sequences

Sequence LengthMass (Da)Tools
Q1LKJ7 [UniParc].

Last modified May 30, 2006. Version 1.
Checksum: 31884C147AF1D894

FASTA36740,152
        10         20         30         40         50         60 
MDLSIPNPVA DATHQAGGNP GGQPLEIDAL IVGAGPVGLF QVFELGLLEI KAHIIDSLKV 

        70         80         90        100        110        120 
VGGQCVELYP DKPIYDIPAV PICTGQELTD NLLKQIEPFS PTFHLGQEVS VVERREDGRF 

       130        140        150        160        170        180 
FVETSLGTRF ITKTIFIAAG VGSFQPRTLK VEGIDKFEGK QLFYRVKDPS RFHGRNLVVV 

       190        200        210        220        230        240 
GGGDSALDWT LDLVGKAESV VMIHRRDGFR AAPASVAKMR ELCEQMEMQF MVGQIGGYEE 

       250        260        270        280        290        300 
KDGVLTEIKV TGADGVTRRM PVDDILVFFG LSPKLGPIAE WGLDLERKQI KVDTEKFETN 

       310        320        330        340        350        360 
IPGIFAVGDI NTYPGKKKLI LSGFHEAALA AFGAAPYIFP DKKIHMQYTT TSPKLHKVLG 


VETPVFD

« Hide

References

[1]"Complete sequence of the chromosome of Ralstonia metallidurans CH34."
US DOE Joint Genome Institute
Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Martinez M., Goltsman E., Pitluck S., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N. expand/collapse author list , Kim E., Mergeay M., Benotmane M.A., Vallaeys T., Michaux A., Monchy S., Dunn J., McCorkle S., Taghavi S., van der Lelie D., Richardson P.
Submitted (APR-2006) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: CH34 / ATCC 43123 / DSM 2839.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000352 Genomic DNA. Translation: ABF09329.1.
RefSeqYP_584598.1. NC_007973.1.

3D structure databases

ProteinModelPortalQ1LKJ7.
ModBaseSearch...

Protein-protein interaction databases

STRINGQ1LKJ7.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID4039274.
GenomeReviewsGene locus Rmet_2452 in contig CP000352_GR.
KEGGrme:Rmet_2452.
PATRIC20289544. VBIRalMet4734_2854.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0492.
HOGENOMHBG669726.
OMAFQVFELG.
ProtClustDBCLSK939521.

Enzyme and pathway databases

BioCycRMET266264:RMET_2452-MONOMER.

Family and domain databases

HAMAPMF_01685. FENR2.
[Tree]
InterProIPR013027. FAD_pyr_nucl-diS_OxRdtase.
IPR022890. Fd--NADP_Rdtase_type_2.
IPR023753. Pyr_nucl-diS_OxRdtase_FAD/NAD.
IPR001327. Pyr_OxRdtase_NAD-bd_dom.
IPR000103. Pyridine_nuc-diS_OxRdtase_2.
[Graphical view]
KOK00384.
PANTHERPTHR22912:SF53. PTHR22912:SF53. 1 hit.
PfamPF00070. Pyr_redox. 1 hit.
PF07992. Pyr_redox_2. 1 hit.
[Graphical view]
PRINTSPR00368. FADPNR.
PR00469. PNDRDTASEII.
ProtoNetSearch...

Entry information

Entry nameFENR2_RALME
AccessionPrimary (citable) accession number: Q1LKJ7
Entry history
Integrated into UniProtKB/Swiss-Prot: March 3, 2009
Last sequence update: May 30, 2006
Last modified: January 25, 2012
This is version 44 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

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