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Q1LJX3 (Q1LJX3_RALME) Unreviewed, UniProtKB/TrEMBL

Last modified January 25, 2012. Version 54. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Serine hydroxymethyltransferase HAMAP MF_00051
Short name=SHMT HAMAP MF_00051
Short name=Serine methylase HAMAP MF_00051
EC=2.1.2.1 HAMAP MF_00051
Gene names
Name:glyA HAMAP MF_00051
Ordered Locus Names:Rmet_2680
OrganismRalstonia metallidurans (strain CH34 / ATCC 43123 / DSM 2839) [Complete proteome] [HAMAP]
Taxonomic identifier266264 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Betaproteobacteria › Burkholderiales › Burkholderiaceae › Cupriavidus

Protein attributes

Sequence length508 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Interconversion of serine and glycine By similarity. HAMAP MF_00051

Catalytic activity

5,10-methylenetetrahydrofolate + glycine + H2O = tetrahydrofolate + L-serine. HAMAP MF_00051

Cofactor

Pyridoxal phosphate By similarity. HAMAP MF_00051

Pathway

One-carbon metabolism; tetrahydrofolate interconversion. HAMAP MF_00051

Subunit structure

Homotetramer By similarity. HAMAP MF_00051

Subcellular location

Cytoplasm By similarity HAMAP MF_00051.

Sequence similarities

Belongs to the SHMT family. HAMAP MF_00051

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Amino acid modifications

Modified residue3231N6-(pyridoxal phosphate)lysine By similarity HAMAP MF_00051

Sequences

Sequence LengthMass (Da)Tools
Q1LJX3 [UniParc].

Last modified May 30, 2006. Version 1.
Checksum: 80E17F405A19C120

FASTA50855,370
        10         20         30         40         50         60 
MRDWRSQWVL PRGSASSLGV IFDAPAARLG SEWEAGCALH RLVAFSRPRC WTPVPSPRAL 

        70         80         90        100        110        120 
IRENPAIQSS VDRHPVFVPA VPSALPFKQT SHAMFERSRF TIEQIDPEVF AAIQKENQRQ 

       130        140        150        160        170        180 
EDHIELIASE NYTSPAVMAA QGSQLTNKYA EGYPGKRYYG GCEYVDVVEQ LAIDRVKQLF 

       190        200        210        220        230        240 
GAEAANVQPN SGSQANQGVF FAMLKPGDTI MGMSLAEGGH LTHGMALNMS GKWFNVVSYG 

       250        260        270        280        290        300 
LNAQEDIDYD ALEKLAHEKK PKLIIAGASA FALRIDFERI AKVAKAVGAY FMVDMAHYAG 

       310        320        330        340        350        360 
LIAAGVYPNP VPHADFVTTT THKSLRGPRG GVILMKAEHE KAINSAIFPG IQGGPLMHVI 

       370        380        390        400        410        420 
AGKAVAFKEA LQPDFKAYQE QVVKNAAALA ETLIARGLRI VSGRTESHVM LVDLRAKKIT 

       430        440        450        460        470        480 
GKEAEKILGD AHITVNKNAI PNDPEKPFVT SGIRLGSPAM TTRGFKEEEA RQVANLIADV 

       490        500 
LDNPHDEANI AAVREQVAAL TRRFPVYG

« Hide

References

[1]"Complete sequence of the chromosome of Ralstonia metallidurans CH34."
Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Martinez M., Goltsman E., Pitluck S., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N. expand/collapse author list , Kim E., Mergeay M., Benotmane M.A., Vallaeys T., Michaux A., Monchy S., Dunn J., McCorkle S., Taghavi S., van der Lelie D., Richardson P.
Submitted (APR-2006) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: CH34 / ATCC 43123 / DSM 2839.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000352 Genomic DNA. Translation: ABF09553.1.
RefSeqYP_584822.1. NC_007973.1.

3D structure databases

ProteinModelPortalQ1LJX3.
SMRQ1LJX3. Positions 97-508.
ModBaseSearch...

Protein-protein interaction databases

STRINGQ1LJX3.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID4039505.
GenomeReviewsGene locus Rmet_2680 in contig CP000352_GR.
KEGGrme:Rmet_2680.
PATRIC20290001. VBIRalMet4734_3078.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0112.
HOGENOMHBG301263.
OMARIDFERI.
PhylomeDBQ1LJX3.

Enzyme and pathway databases

BioCycRMET266264:RMET_2680-MONOMER.

Family and domain databases

HAMAPMF_00051. SHMT.
[Tree]
InterProIPR015424. PyrdxlP-dep_Trfase_major_dom.
IPR015421. PyrdxlP-dep_Trfase_major_sub1.
IPR015422. PyrdxlP-dep_Trfase_major_sub2.
IPR001085. Ser_HO-MeTrfase.
IPR019798. Ser_HO-MeTrfase_PLP_BS.
[Graphical view]
Gene3DG3DSA:3.40.640.10. PyrdxlP-dep_Trfase_major_sub1. 1 hit.
G3DSA:3.90.1150.10. PyrdxlP-dep_Trfase_major_sub2. 1 hit.
KOK00600.
PANTHERPTHR11680. Gly_HO-Metrfase. 1 hit.
PfamPF00464. SHMT. 1 hit.
[Graphical view]
PIRSFPIRSF000412. SHMT. 1 hit.
SUPFAMSSF53383. PyrdxlP-dep_Trfase_major. 1 hit.
PROSITEPS00096. SHMT. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameQ1LJX3_RALME
AccessionPrimary (citable) accession number: Q1LJX3
Entry history
Integrated into UniProtKB/TrEMBL: May 30, 2006
Last sequence update: May 30, 2006
Last modified: January 25, 2012
This is version 54 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info