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Q1LJC9 (Q1LJC9_RALME) Unreviewed, UniProtKB/TrEMBL

Last modified June 11, 2014. Version 67. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Protein attributes

Sequence length384 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate By similarity. HAMAP-Rule MF_00567 SAAS SAAS003473

Catalytic activity

Glycerone phosphate + iminosuccinate = pyridine-2,3-dicarboxylate + 2 H2O + phosphate. HAMAP-Rule MF_00567 SAAS SAAS003473

Cofactor

Binds 1 4Fe-4S cluster per subunit By similarity. HAMAP-Rule MF_00567 SAAS SAAS003473

Pathway

Cofactor biosynthesis; NAD(+) biosynthesis; quinolinate from iminoaspartate: step 1/1. HAMAP-Rule MF_00567 SAAS SAAS003473

Subunit structure

Homodimer By similarity. HAMAP-Rule MF_00567 SAAS SAAS003473

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00567 SAAS SAAS003473.

Sequence similarities

Belongs to the quinolinate synthase A family. Type 1 subfamily. HAMAP-Rule MF_00567

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Sites

Binding site651Iminoaspartate By similarity HAMAP-Rule MF_00567
Binding site861Iminoaspartate; via amide nitrogen By similarity HAMAP-Rule MF_00567
Binding site1571Iminoaspartate By similarity HAMAP-Rule MF_00567
Binding site1741Iminoaspartate By similarity HAMAP-Rule MF_00567
Binding site2441Iminoaspartate By similarity HAMAP-Rule MF_00567
Binding site2611Iminoaspartate By similarity HAMAP-Rule MF_00567

Sequences

Sequence LengthMass (Da)Tools
Q1LJC9 [UniParc].

Last modified May 30, 2006. Version 1.
Checksum: 9B09C4BD4C736272

FASTA38441,438
        10         20         30         40         50         60 
MTPQTIKSVE FEKPNLTDPD AAAGGSCVAH AWAKVPPALT PDERQALKSR IRKLLKERNA 

        70         80         90        100        110        120 
VLVAHYYVDA DLQDLAEETG GCVSDSLEMA RFGRDHDAKT LVVAGVRFMG ETAKILSPEK 

       130        140        150        160        170        180 
TILMPDLDAT CSLDLGCPAD DFSAFCDAHP DRTVVVYANT SAAVKARADW MVTSSIGLKI 

       190        200        210        220        230        240 
VEHLHARGEK ILWAPDKHLG SYIQQQTGAD MLLWQGSCLV HDEFKGIELD LLRREHPKAK 

       250        260        270        280        290        300 
ILVHPESPAN VVAQADVVGS TSQLIAAAQQ LDANEFIVAT DNGILHKMRM AAPGKMFIEA 

       310        320        330        340        350        360 
PTAGNSATCK SCAHCPWMAM NALTNLAEVL ETGRNEIHVD ADIGRRAVTC INRMLDFAAQ 

       370        380 
QKANVRPAAD LAKESALFSG VGPA 

« Hide

References

[1]"Complete sequence of the chromosome of Ralstonia metallidurans CH34."
US DOE Joint Genome Institute
Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Martinez M., Goltsman E., Pitluck S., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N. expand/collapse author list , Kim E., Mergeay M., Benotmane M.A., Vallaeys T., Michaux A., Monchy S., Dunn J., McCorkle S., Taghavi S., van der Lelie D., Richardson P.
Submitted (APR-2006) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: CH34 / ATCC 43123 / DSM 2839.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP000352 Genomic DNA. Translation: ABF09747.1.
RefSeqYP_585016.1. NC_007973.1.

3D structure databases

ProteinModelPortalQ1LJC9.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING266264.Rmet_2874.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaABF09747; ABF09747; Rmet_2874.
GeneID4039702.
KEGGrme:Rmet_2874.
PATRIC20290375. VBIRalMet4734_3263.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0379.
HOGENOMHOG000222769.
KOK03517.
OMAKTVLMPT.
OrthoDBEOG6DJZ56.

Enzyme and pathway databases

BioCycCMET266264:GJ5G-3069-MONOMER.
UniPathwayUPA00253; UER00327.

Family and domain databases

HAMAPMF_00567. NadA_type1.
InterProIPR003473. NadA.
IPR023513. Quinolinate_synth_A_type1.
[Graphical view]
PfamPF02445. NadA. 1 hit.
[Graphical view]
TIGRFAMsTIGR00550. nadA. 1 hit.
ProtoNetSearch...

Entry information

Entry nameQ1LJC9_RALME
AccessionPrimary (citable) accession number: Q1LJC9
Entry history
Integrated into UniProtKB/TrEMBL: May 30, 2006
Last sequence update: May 30, 2006
Last modified: June 11, 2014
This is version 67 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)