Reviewed, UniProtKB/Swiss-Prot Q1LIU6 (UBIC_RALME)

Names and origin

Protein names

Recommended name:
    Probable chorismate--pyruvate lyase
      Short name=CL
      Short name=CPL
    EC=4.1.3.40

Gene names

Name:	ubiC
Ordered Locus Names:	Rmet_3058

Organism

Ralstonia metallidurans (strain CH34 / ATCC 43123 / DSM 2839) [Complete proteome] [HAMAP]

Taxonomic identifier

266264 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Betaproteobacteria › Burkholderiales › Burkholderiaceae › Cupriavidus

Protein attributes

Sequence length	214 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Function	Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4-hydroxybenzoate (4HB) for the ubiquinone pathway By similarity.
Catalytic activity	Chorismate = 4-hydroxybenzoate + pyruvate. HAMAP MF_01632
Pathway	Cofactor biosynthesis; ubiquinone biosynthesis. HAMAP MF_01632
Subcellular location	Cytoplasm By similarity.
Sequence similarities	Belongs to the ubiC family.

Ontologies

Keywords
Biological process	Ubiquinone biosynthesis
Cellular component	Cytoplasm
Ligand	Pyruvate
Molecular function	Lyase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	pyruvate biosynthetic process Inferred from electronic annotation. Source: HAMAP ubiquinone biosynthetic process Inferred from electronic annotation. Source: HAMAP
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	chorismate lyase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 214	214	Probable chorismate--pyruvate lyase HAMAP MF_01632		PRO_0000255911
Sites
	Binding site	74	1	Substrate By similarity
	Binding site	112	1	Substrate; via amide nitrogen By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q1LIU6-1 [UniParc]. Last modified October 31, 2006. Version 2. Checksum: F1EC498766F0D862	FASTA	214	24,061
	10 20 30 40 50 60 MQKLRAAWHA HLPYDASIPL NQRRWITGEG SLTARLMSAS AAFRVRRLAQ APQLPLADEW 70 80 90 100 110 120 RALGLIRPLP AITREVLLIC DETPAVFAHT IVDPRYARRD WPFLRGLGNR PLGGALFVDP 130 140 150 160 170 180 RVRRDPFQFA RLTPCHPLRQ ALQRVLPALS SEPMLPARRS VFRRGGGAML VTEVFLPDLL 190 200 210 TRAAPENTGA GGTRLPRRID THHTPSKQEE RPES

References

[1]

"Complete sequence of the chromosome of Ralstonia metallidurans CH34." Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Martinez M., Goltsman E., Pitluck S., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N. , Kim E., Mergeay M., Benotmane M.A., Vallaeys T., Michaux A., Monchy S., Dunn J., McCorkle S., Taghavi S., van der Lelie D., Richardson P. Submitted (APR-2006) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBLGenBankDDBJ	CP000352 Genomic DNA. Translation: ABF09930.1. Different initiation.
RefSeq	YP_585199.1.
3D structure databases
ModBase	Search...
Genome annotation databases
GeneID	4039886.
GenomeReviews	Gene locus Rmet_3058 in contig CP000352_GR.
KEGG	rme:Rmet_3058.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	Q1LIU6.
Enzyme and pathway databases
BioCyc	RMET266264:RMET_3058-MON.
Family and domain databases
HAMAP	MF_01632. [Tree]
InterPro	IPR007440. Chorismate_lyase. [Graphical view]
Pfam	PF04345. Chor_lyase. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

UBIC_RALME

Accession

Primary (citable) accession number: Q1LIU6

Entry history

Integrated into UniProtKB/Swiss-Prot:	October 31, 2006
Last sequence update:	October 31, 2006
Last modified:	June 16, 2009
This is version 19 of the entry and version 2 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)