Reviewed, UniProtKB/Swiss-Prot Q1LB18 (GLK_RALME)

Names and origin

Protein names

Recommended name:
    Glucokinase
    EC=2.7.1.2
Alternative name(s):
    Glucose kinase

Gene names

Name:	glk
Ordered Locus Names:	Rmet_5799

Encoded on

Plasmid megaplasmid CH34

Organism

Ralstonia metallidurans (strain CH34 / ATCC 43123 / DSM 2839) [Complete proteome] [HAMAP]

Taxonomic identifier

266264 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Betaproteobacteria › Burkholderiales › Burkholderiaceae › Cupriavidus

Protein attributes

Sequence length	336 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Catalytic activity	ATP + D-glucose = ADP + D-glucose 6-phosphate. HAMAP MF_00524
Subcellular location	Cytoplasm By similarity.
Sequence similarities	Belongs to the bacterial glucokinase family.

Ontologies

Keywords
Biological process	Glycolysis
Cellular component	Cytoplasm
Ligand	ATP-binding Nucleotide-binding
Molecular function	Kinase Transferase
Technical term	Complete proteome Plasmid
Gene Ontology (GO)
Biological process	glycolysis Inferred from electronic annotation. Source: HAMAP
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	ATP binding Inferred from electronic annotation. Source: HAMAP glucokinase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 336	336	Glucokinase HAMAP MF_00524		PRO_0000268781
Regions
	Nucleotide binding	13 – 18	6	ATP Potential

Sequences

	Sequence		Length	Mass (Da)
	Q1LB18-1 [UniParc]. Last modified May 30, 2006. Version 1. Checksum: 47721EFB63A9591E	FASTA	336	35,185
	10 20 30 40 50 60 MTDRAMSYPR ILADVGGTNV RFAMETAPMR IGEITAYKVA EHASLEAAMR LYMLTRSGAA 70 80 90 100 110 120 RPRHAAIGLA NPVTGDQVKL TNHNWAFSVE AMRRALDLDT LVAINDFTSL ALALPYLPDA 130 140 150 160 170 180 SLVQVRDGTA VATAPRALIG PGTGLGVSGL IPAPGGAVAL AGEGGHIEIM PVTDDEWIAW 190 200 210 220 230 240 RAAHDQFGRV SAERLLSGMG LSHIHAALSA EMGTPLEVPL APAQVTDGAM RAGDPVCRRA 250 260 270 280 290 300 FDAFCGMLGS VAADVALVLG ARGGVYLGGG IVPRFVDALR ASTFAERFVA KGRMGSFLAD 310 320 330 VPVYVITAEY PALPGLARAL ADRLEADARR AETSQS

References

[1]

"Complete sequence of the megaplasmid of Ralstonia metallidurans CH34." Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Martinez M., Goltsman E., Pitluck S., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N. , Kim E., Mergeay M., Benotmane M.A., Vallaeys T., Michaux A., Monchy S., Dunn J., McCorkle S., Taghavi S., van der Lelie D., Richardson P. Submitted (APR-2006) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBLGenBankDDBJ	CP000353 Genomic DNA. Translation: ABF12658.1.
RefSeq	YP_587927.1.
3D structure databases
ModBase	Search...
Genome annotation databases
GeneID	4042663.
GenomeReviews	Gene locus Rmet_5799 in contig CP000353_GR.
KEGG	rme:Rmet_5799.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	Q1LB18.
OMA	Q1LB18. VDIGGTH.
Enzyme and pathway databases
BioCyc	RMET266264:RMET_5799-MON.
Family and domain databases
HAMAP	MF_00524. [Tree]
InterPro	IPR003836. Glucokinase. [Graphical view]
Pfam	PF02685. Glucokinase. 1 hit. [Graphical view]
TIGRFAMs	TIGR00749. glk. 1 hit.
ProtoNet	Search...

Entry information

Entry name

GLK_RALME

Accession

Primary (citable) accession number: Q1LB18

Entry history

Integrated into UniProtKB/Swiss-Prot:	December 12, 2006
Last sequence update:	May 30, 2006
Last modified:	June 16, 2009
This is version 17 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)