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Protein

Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta, chloroplastic

Gene

accD

Organism
Helianthus annuus (Common sunflower)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO2 group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.UniRule annotation

Catalytic activityi

ATP + acetyl-CoA + HCO3- = ADP + phosphate + malonyl-CoA.UniRule annotation

Cofactori

Zn2+UniRule annotationNote: Binds 1 zinc ion per subunit.UniRule annotation

Pathwayi: malonyl-CoA biosynthesis

This protein is involved in step 1 of the subpathway that synthesizes malonyl-CoA from acetyl-CoA.UniRule annotation
Proteins known to be involved in this subpathway in this organism are:
  1. Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta, chloroplastic (accD), Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta (accD)
This subpathway is part of the pathway malonyl-CoA biosynthesis, which is itself part of Lipid metabolism.
View all proteins of this organism that are known to be involved in the subpathway that synthesizes malonyl-CoA from acetyl-CoA, the pathway malonyl-CoA biosynthesis and in Lipid metabolism.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Metal bindingi220ZincUniRule annotation1
Metal bindingi223ZincUniRule annotation1
Metal bindingi239ZincUniRule annotation1
Metal bindingi242ZincUniRule annotation1

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Zinc fingeri220 – 242C4-typeUniRule annotationAdd BLAST23

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionLigase
Biological processFatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism
LigandATP-binding, Metal-binding, Nucleotide-binding, Zinc

Enzyme and pathway databases

UniPathwayiUPA00655; UER00711.

Names & Taxonomyi

Protein namesi
Recommended name:
Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta, chloroplasticUniRule annotation (EC:6.4.1.2UniRule annotation)
Short name:
ACCase subunit betaUniRule annotation
Short name:
Acetyl-CoA carboxylase carboxyltransferase subunit betaUniRule annotation
Gene namesi
Name:accDUniRule annotation
Encoded oniPlastid; Chloroplast
OrganismiHelianthus annuus (Common sunflower)
Taxonomic identifieri4232 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaeasteridscampanulidsAsteralesAsteraceaeAsteroideaeHeliantheae allianceHeliantheaeHelianthus

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Chloroplast Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertion Graphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Chloroplast, Plastid

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003591431 – 480Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta, chloroplasticAdd BLAST480

Interactioni

Subunit structurei

Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein, biotin carboxylase and 2 subunits each of ACCase subunit alpha and ACCase plastid-coded subunit beta (accD).By similarity

Structurei

3D structure databases

ProteinModelPortaliQ1KXV0.
SMRiQ1KXV0.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini216 – 480CoA carboxyltransferase N-terminalPROSITE-ProRule annotationAdd BLAST265

Sequence similaritiesi

Belongs to the AccD/PCCB family.UniRule annotation

Zinc finger

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Zinc fingeri220 – 242C4-typeUniRule annotationAdd BLAST23

Keywords - Domaini

Zinc-finger

Phylogenomic databases

KOiK01963.

Family and domain databases

HAMAPiMF_01395. AcetylCoA_CT_beta. 1 hit.
InterProiView protein in InterPro
IPR034733. AcCoA_carboxyl.
IPR000438. Acetyl_CoA_COase_Trfase_b_su.
IPR029045. ClpP/crotonase-like_dom_sf.
IPR011762. COA_CT_N.
PfamiView protein in Pfam
PF01039. Carboxyl_trans. 1 hit.
PRINTSiPR01070. ACCCTRFRASEB.
SUPFAMiSSF52096. SSF52096. 1 hit.
TIGRFAMsiTIGR00515. accD. 1 hit.
PROSITEiView protein in PROSITE
PS50980. COA_CT_NTER. 1 hit.

Sequencei

Sequence statusi: Complete.

Q1KXV0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKRWWLNSML FKKEFEHRCR LSKSTSSLGP IENASESKDP NINDTDKNIQ
60 70 80 90 100
SWGGHDNYSN VDLFFGVKDL RNLISDDTFL VKDSNGDIYS LYFDIENHIF
110 120 130 140 150
EIDNDHPELE SSFYRNSSYL NNGSKSKNPE HDPYMNDTQY TWNNHINSCI
160 170 180 190 200
DSYLQSQICI DSYIVSGSDN SSNNYISSSI CGESGNSSKN EDARTSDPII
210 220 230 240 250
RESSTDLDVT QKYRHLWVQC ENCYGLNYKK FFKSKMNLCE QCGYHLKMSS
260 270 280 290 300
SDRIELSIDP GTWEPMDEDM VSLDPIEFHS EEEPYKNRID SYQRKTGLTE
310 320 330 340 350
AVQTGIGQLD GINVAIAVMD FQFMGGSMGS VVGEKITRLI EYATKEFLPL
360 370 380 390 400
IIVCASGGAR MQEGSLSLMQ MAKISSALYD YQSNKKLFYV PILTSPTTGG
410 420 430 440 450
VTASFGMLGD IIIAEPNAYI AFAGKRVIEQ TLNKTVPDGS QAAEYLFQKG
460 470 480
LFDLIVPRNP LKSVLSELFQ LHTFFPLNQN
Length:480
Mass (Da):54,284
Last modified:May 30, 2006 - v1
Checksum:i87998D2753819DE2
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
DQ383815 Genomic DNA. Translation: ABD47155.1.
RefSeqiYP_588126.1. NC_007977.1.

Genome annotation databases

EnsemblPlantsiOTF84760; OTF84760; HannXRQ_CPg0580021.
OTG07126; OTG07126; HannXRQ_Chr11g0326811.
OTG10584; OTG10584; HannXRQ_Chr10g0289251.
OTG37584; OTG37584; HannXRQ_Chr01g0020371.
GeneIDi4055710.
GrameneiOTF84760; OTF84760; HannXRQ_CPg0580021.
OTG07126; OTG07126; HannXRQ_Chr11g0326811.
OTG10584; OTG10584; HannXRQ_Chr10g0289251.
OTG37584; OTG37584; HannXRQ_Chr01g0020371.
KEGGihan:4055710.

Similar proteinsi

Entry informationi

Entry nameiACCD_HELAN
AccessioniPrimary (citable) accession number: Q1KXV0
Entry historyiIntegrated into UniProtKB/Swiss-Prot: January 20, 2009
Last sequence update: May 30, 2006
Last modified: February 28, 2018
This is version 48 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program