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Protein
Submitted name:

Toll-like receptor 3

Gene
N/A
Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

ReceptorImported

Names & Taxonomyi

Protein namesi
Submitted name:
Toll-like receptor 3Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

PTM / Processingi

Proteomic databases

PaxDbiQ1KMK2.

Expressioni

Gene expression databases

BgeeiQ1KMK2.

Interactioni

Protein-protein interaction databases

STRINGi9606.ENSP00000296795.

Family & Domainsi

Phylogenomic databases

eggNOGiKOG4641. Eukaryota.
COG4886. LUCA.

Family and domain databases

Gene3Di3.80.10.10. 1 hit.
InterProiIPR032675. L_dom-like.
IPR001611. Leu-rich_rpt.
IPR003591. Leu-rich_rpt_typical-subtyp.
IPR027173. TLR3.
[Graphical view]
PANTHERiPTHR24365:SF5. PTHR24365:SF5. 1 hit.
PfamiPF13855. LRR_8. 1 hit.
[Graphical view]
SMARTiSM00369. LRR_TYP. 3 hits.
[Graphical view]
SUPFAMiSSF52058. SSF52058. 1 hit.

Sequencei

Sequence statusi: Fragment.

Q1KMK2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
NPGGPIYFLK GLSHLHILNL ESNGFDEIPV EVFKDLFELK IIDLGLNNLN
60 70 80 90 100
TLPASVFNNQ VSLKSLNLQK NLITSVEKKV FGPAFRNLTE LDMRFNPFDC
110 120
TCESIAWFVN WINETHTNIP ELSSHYL
Length:127
Mass (Da):14,478
Last modified:May 30, 2006 - v1
Checksum:i56A04FE20EAF2B5D
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei1 – 11Imported
Non-terminal residuei127 – 1271Imported

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
DQ470075 mRNA. Translation: ABF06633.1.
DQ470076 mRNA. Translation: ABF06634.1.
DQ470077 mRNA. Translation: ABF06635.1.
DQ470078 mRNA. Translation: ABF06636.1.
DQ470079 mRNA. Translation: ABF06637.1.
UniGeneiHs.657724.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
DQ470075 mRNA. Translation: ABF06633.1.
DQ470076 mRNA. Translation: ABF06634.1.
DQ470077 mRNA. Translation: ABF06635.1.
DQ470078 mRNA. Translation: ABF06636.1.
DQ470079 mRNA. Translation: ABF06637.1.
UniGeneiHs.657724.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9606.ENSP00000296795.

Proteomic databases

PaxDbiQ1KMK2.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Phylogenomic databases

eggNOGiKOG4641. Eukaryota.
COG4886. LUCA.

Gene expression databases

BgeeiQ1KMK2.

Family and domain databases

Gene3Di3.80.10.10. 1 hit.
InterProiIPR032675. L_dom-like.
IPR001611. Leu-rich_rpt.
IPR003591. Leu-rich_rpt_typical-subtyp.
IPR027173. TLR3.
[Graphical view]
PANTHERiPTHR24365:SF5. PTHR24365:SF5. 1 hit.
PfamiPF13855. LRR_8. 1 hit.
[Graphical view]
SMARTiSM00369. LRR_TYP. 3 hits.
[Graphical view]
SUPFAMiSSF52058. SSF52058. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. Megret F., Prehaud C.
    Submitted (MAR-2006) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.

Entry informationi

Entry nameiQ1KMK2_HUMAN
AccessioniPrimary (citable) accession number: Q1KMK2
Entry historyi
Integrated into UniProtKB/TrEMBL: May 30, 2006
Last sequence update: May 30, 2006
Last modified: May 11, 2016
This is version 51 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.