Q1KLZ0 (Q1KLZ0_HUMAN) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
HCG15971, isoform CRA_a EMBL EAW87341.1

Submitted name:
PS1TP5-binding protein 1 EMBL ABF01018.1

Gene names

Name:	PS1TP5BP1 EMBL ABF01018.1
ORF Names:	hCG_15971 EMBL EAW87341.1

Organism

Homo sapiens (Human) EMBL ABF01018.1

Taxonomic identifier

9606 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Euarchontoglires › Primates › Haplorrhini › Simiiformes › Catarrhini › Hominoidea › Hominidae › Homininae › Homo

Protein attributes

Sequence length	375 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

General annotation (Comments)

Sequence similarities

Belongs to the actin family. RuleBase RU000487

Ontologies

Keywords
Cellular component	Cytoplasm Cytoskeleton SAAS SAAS020902
Ligand	ATP-binding SAAS SAAS020902 Nucleotide-binding
Gene Ontology (GO)
Biological_process	axonogenesis Inferred from electronic annotation. Source: Compara
Cellular_component	axon Inferred from electronic annotation. Source: Compara cortical cytoskeleton Inferred from electronic annotation. Source: Compara cytosol Inferred from electronic annotation. Source: Compara postsynaptic density Inferred from electronic annotation. Source: Compara protein complex Inferred from electronic annotation. Source: Compara
Molecular_function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q1KLZ0 [UniParc]. Last modified May 30, 2006. Version 1. Checksum: 6AFD05CA94E360E2	FASTA	375	41,737
	10 20 30 40 50 60 MDDDIAALVV DNGSGMCKAG FAGDDAPRAV FPSIVGRPRH QGVMVGMGQK DSYVGDEAQS 70 80 90 100 110 120 KRGILTLKYP IEHGIVTNWD DMEKIWHHTF YNELRVAPEE HPVLLTEAPL NPKANREKMT 130 140 150 160 170 180 QIMFETFNTP AMYVAIQAVL SLYASGRTTG IVMDSGDGVT HTVPIYEGYA LPHAILRLDL 190 200 210 220 230 240 AGRDLTDYLM KILTERGYSF TTTAEREIVR DIKEKLCYVA LDFEQEMATA ASSSSLEKSY 250 260 270 280 290 300 ELPDGQVITI GNERFRCPEA LFQPSFLGME SCGIHETTFN SIMKCDVDIR KDLYANTVLS 310 320 330 340 350 360 GGTTMYPGIA DRMQKEITAL APSTMKIKII APPERKYSVW IGGSILASLS TFQQMWISKQ 370 EYDESGPSIV HRKCF

References

[1]	Mural R.J., Istrail S., Sutton G., Florea L., Halpern A.L., Mobarry C.M., Lippert R., Walenz B., Shatkay H., Dew I., Miller J.R., Flanigan M.J., Edwards N.J., Bolanos R., Fasulo D., Halldorsson B.V., Hannenhalli S., Turner R. , Yooseph S., Lu F., Nusskern D.R., Shue B.C., Zheng X.H., Zhong F., Delcher A.L., Huson D.H., Kravitz S.A., Mouchard L., Reinert K., Remington K.A., Clark A.G., Waterman M.S., Eichler E.E., Adams M.D., Hunkapiller M.W., Myers E.W., Venter J.C. Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE.
[2]	"Cloning and analysis of the cDNA of PS1TP5-binding protein 1." Zhang J.-K., Guo J., Cheng J., Hong Y., Wei H.-S. Submitted (APR-2006) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	DQ471327 mRNA. Translation: ABF01018.1. CH471144 Genomic DNA. Translation: EAW87341.1.
IPI	IPI00021439.
RefSeq	NP_001092.1. NM_001101.3.
UniGene	Hs.520640.
3D structure databases
ProteinModelPortal	Q1KLZ0.
ModBase	Search...
Protein-protein interaction databases
STRING	Q1KLZ0.
Proteomic databases
PRIDE	Q1KLZ0.
Protocols and materials databases
DNASU	60.
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	60.
KEGG	hsa:60.
Organism-specific databases
CTD	60.
PharmGKB	PA24457.
Phylogenomic databases
HOVERGEN	HBG003771.
KO	K05692.
OMA	IKNLMER.
PhylomeDB	Q1KLZ0.
Gene expression databases
ArrayExpress	Q1KLZ0.
Bgee	Q1KLZ0.
Family and domain databases
InterPro	IPR004000. Actin-related. IPR020902. Actin/actin-like_CS. IPR004001. Actin_CS. [Graphical view]
PANTHER	PTHR11937. PTHR11937. 1 hit.
Pfam	PF00022. Actin. 1 hit. [Graphical view]
PRINTS	PR00190. ACTIN.
SMART	SM00268. ACTIN. 1 hit. [Graphical view]
PROSITE	PS00406. ACTINS_1. 1 hit. PS00432. ACTINS_2. 1 hit. PS01132. ACTINS_ACT_LIKE. 1 hit. [Graphical view]
ProtoNet	Search...
Other
ChiTaRS	ACTB. human.
GenomeRNAi	60.
NextBio	253.
PMAP-CutDB	Q1KLZ0.

Entry information

Entry name

Q1KLZ0_HUMAN

Accession

Primary (citable) accession number: Q1KLZ0

Entry history

Integrated into UniProtKB/TrEMBL:	May 30, 2006
Last sequence update:	May 30, 2006
Last modified:	May 1, 2013
This is version 65 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.