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Protein

Homeobox protein Hox-A5a

Gene

hoxa5a

Organism
Takifugu rubripes (Japanese pufferfish) (Fugu rubripes)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.By similarity

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
DNA bindingi198 – 257HomeoboxPROSITE-ProRule annotationAdd BLAST60

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionDevelopmental protein, DNA-binding
Biological processTranscription, Transcription regulation

Names & Taxonomyi

Protein namesi
Recommended name:
Homeobox protein Hox-A5a
Gene namesi
Name:hoxa5a
OrganismiTakifugu rubripes (Japanese pufferfish) (Fugu rubripes)
Taxonomic identifieri31033 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiActinopterygiiNeopterygiiTeleosteiNeoteleosteiAcanthomorphataEupercariaTetraodontiformesTetradontoideaTetraodontidaeTakifugu
Proteomesi
  • UP000005226 Componenti: Unplaced

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002659671 – 274Homeobox protein Hox-A5aAdd BLAST274

Proteomic databases

PRIDEiQ1KL14

Interactioni

Protein-protein interaction databases

STRINGi31033.ENSTRUP00000046718

Structurei

3D structure databases

ProteinModelPortaliQ1KL14
SMRiQ1KL14
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Motif

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Motifi180 – 185Antp-type hexapeptide6

Sequence similaritiesi

Belongs to the Antp homeobox family.Curated

Keywords - Domaini

Homeobox

Phylogenomic databases

eggNOGiKOG0489 Eukaryota
ENOG410ZTBY LUCA
GeneTreeiENSGT00910000143983
InParanoidiQ1KL14
OMAiLKSMNMA
OrthoDBiEOG091G09XD
TreeFamiTF316310

Family and domain databases

CDDicd00086 homeodomain, 1 hit
InterProiView protein in InterPro
IPR009057 Homeobox-like_sf
IPR017995 Homeobox_antennapedia
IPR001827 Homeobox_Antennapedia_CS
IPR017970 Homeobox_CS
IPR001356 Homeobox_dom
IPR020479 Homeobox_metazoa
PfamiView protein in Pfam
PF00046 Homeobox, 1 hit
PRINTSiPR00025 ANTENNAPEDIA
PR00024 HOMEOBOX
SMARTiView protein in SMART
SM00389 HOX, 1 hit
SUPFAMiSSF46689 SSF46689, 1 hit
PROSITEiView protein in PROSITE
PS00032 ANTENNAPEDIA, 1 hit
PS00027 HOMEOBOX_1, 1 hit
PS50071 HOMEOBOX_2, 1 hit

Sequencei

Sequence statusi: Complete.

Q1KL14-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSSYFVNSFC GRYPNGADFQ LHNYGDHDTA DEQYRNSTTM HSTRYGYGYN
60 70 80 90 100
GMDLTVGRDG TGHFVGNERT RGYSENHSAT AASVESVRYN QTTNTTGTSS
110 120 130 140 150
LSPPPDPLPC SSVSSASPVT ETQPQHRVVK NSVTTPCSSS SGGTLLVNRD
160 170 180 190 200
CASKSSPLEE EKPAGGATPQ NVNDSTQPQI YPWMRKIHIS HELSGPEGKR
210 220 230 240 250
ARTAYTRYQT LELEKEFHFN RYLTRRRRIE IAHALCLSER QIKIWFQNRR
260 270
MKWKKDNKLK SMNMASAGGG VYRP
Length:274
Mass (Da):30,717
Last modified:May 30, 2006 - v1
Checksum:i9C898A7161913F1E
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
DQ481663 Genomic DNA Translation: ABF22380.1

Genome annotation databases

EnsembliENSTRUT00000046876; ENSTRUP00000046718; ENSTRUG00000018252

Similar proteinsi

Entry informationi

Entry nameiHXA5A_TAKRU
AccessioniPrimary (citable) accession number: Q1KL14
Entry historyiIntegrated into UniProtKB/Swiss-Prot: December 12, 2006
Last sequence update: May 30, 2006
Last modified: May 23, 2018
This is version 80 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Vertebrate homeotic Hox proteins
    Nomenclature of vertebrate homeotic Hox proteins and list of entries
  2. SIMILARITY comments
    Index of protein domains and families

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