Q1KL13 (HXA4A_TAKRU) Reviewed, UniProtKB/Swiss-Prot
Last modified
December 14, 2011.
Version 33.
History...
Names·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order
Names·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize orderNames and origin
| Protein names | Recommended name: Homeobox protein Hox-A4a | ||
| Gene names |
| ||
| Organism | Takifugu rubripes (Japanese pufferfish) (Fugu rubripes) | ||
| Taxonomic identifier | 31033 [NCBI] | ||
| Taxonomic lineage | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Actinopterygii › Neopterygii › Teleostei › Euteleostei › Neoteleostei › Acanthomorpha › Acanthopterygii › Percomorpha › Tetraodontiformes › Tetradontoidea › Tetraodontidae › Takifugu |
Protein attributes
| Sequence length | 255 AA. |
| Sequence status | Complete. |
| Protein existence | Inferred from homology |
General annotation (Comments)
| Function | Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis By similarity. |
| Subcellular location | Nucleus By similarity. |
| Sequence similarities | Belongs to the Antp homeobox family. Deformed subfamily. Contains 1 homeobox DNA-binding domain. |
Ontologies
| Keywords | |
|---|---|
| Biological process | Transcription Transcription regulation |
| Cellular component | Nucleus |
| Domain | Homeobox |
| Ligand | DNA-binding |
| Molecular function | Developmental protein |
| Gene Ontology (GO) | |
| Biological process | multicellular organismal development Inferred from electronic annotation. Source: UniProtKB-KW transcription, DNA-dependentInferred from electronic annotation. Source: UniProtKB-KW |
| Cellular component | nucleus Inferred from electronic annotation. Source: UniProtKB-SubCell |
| Molecular function | sequence-specific DNA binding Inferred from electronic annotation. Source: InterPro sequence-specific DNA binding transcription factor activityInferred from electronic annotation. Source: InterPro |
| Complete GO annotation... | |
Sequence annotation (Features)
Sequences
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References
| [1] | "Highly conserved syntenic blocks at the vertebrate Hox loci and conserved regulatory elements within and outside Hox gene clusters." Lee A.P., Koh E.G.L., Tay A., Brenner S., Venkatesh B. Proc. Natl. Acad. Sci. U.S.A. 103:6994-6999(2006) [PubMed: 16636282] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]. |
Cross-references
Sequence databases | |
|---|---|
| EMBL GenBank DDBJ | DQ481663 Genomic DNA. Translation: ABF22381.1. |
3D structure databases | |
| ProteinModelPortal | Q1KL13. |
| SMR | Q1KL13. Positions 122-209. |
| ModBase | Search... |
Protein-protein interaction databases | |
| STRING | Q1KL13. |
Protocols and materials databases | |
| StructuralBiologyKnowledgebase | Search... |
Phylogenomic databases | |
| eggNOG | fiNOG06757. |
| PhylomeDB | Q1KL13. |
Family and domain databases | |
| InterPro | IPR001356. Homeobox. IPR017995. Homeobox_antennapedia. IPR001827. Homeobox_Antennapedia_CS. IPR017970. Homeobox_CS. IPR020479. Homeobox_eu. IPR009057. Homeodomain-like. IPR012287. Homeodomain-rel. [Graphical view] |
| Gene3D | G3DSA:1.10.10.60. Homeodomain-rel. 1 hit. |
| Pfam | PF00046. Homeobox. 1 hit. [Graphical view] |
| PRINTS | PR00025. ANTENNAPEDIA. PR00024. HOMEOBOX. |
| SMART | SM00389. HOX. 1 hit. [Graphical view] |
| SUPFAM | SSF46689. Homeodomain_like. 1 hit. |
| PROSITE | PS00032. ANTENNAPEDIA. 1 hit. PS00027. HOMEOBOX_1. 1 hit. PS50071. HOMEOBOX_2. 1 hit. [Graphical view] |
| ProtoNet | Search... |
Entry information
| Entry name | HXA4A_TAKRU | ||||||||
| Accession | Primary (citable) accession number: Q1KL13 | ||||||||
| Entry history |
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| Entry status | Reviewed (UniProtKB/Swiss-Prot) | ||||||||
| Annotation program | Chordata Protein Annotation Program | ||||||||
Relevant documents
| Vertebrate homeotic Hox proteins Nomenclature of vertebrate homeotic Hox proteins and list of entries |
| SIMILARITY comments Index of protein domains and families |

Clusters with