Reviewed, UniProtKB/Swiss-Prot Q1KKZ3 (HXA9B_TAKRU)

Names and origin

Protein names

Recommended name:
    Homeobox protein Hox-A9b

Gene names

Name:

hoxa9b

Organism

Takifugu rubripes (Japanese pufferfish) (Fugu rubripes)

Taxonomic identifier

31033 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Actinopterygii › Neopterygii › Teleostei › Euteleostei › Neoteleostei › Acanthomorpha › Acanthopterygii › Percomorpha › Tetraodontiformes › Tetradontoidea › Tetraodontidae › Takifugu

Protein attributes

Sequence length	249 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Function	Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis By similarity.
Subcellular location	Nucleus By similarity.
Sequence similarities	Belongs to the Abd-B homeobox family. Contains 1 homeobox DNA-binding domain.

Ontologies

Keywords
Biological process	Transcription Transcription regulation
Cellular component	Nucleus
Domain	Homeobox
Ligand	DNA-binding
Molecular function	Developmental protein
Gene Ontology (GO)
Biological process	multicellular organismal development Inferred from electronic annotation. Source: UniProtKB-KW regulation of transcription, DNA-dependent Inferred from electronic annotation. Source: InterPro transcription Inferred from electronic annotation. Source: UniProtKB-KW
Cellular component	nucleus Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	sequence-specific DNA binding Inferred from electronic annotation. Source: InterPro transcription activator activity Inferred from electronic annotation. Source: InterPro transcription factor activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 249	249	Homeobox protein Hox-A9b		PRO_0000265968

Sequences

	Sequence		Length	Mass (Da)
	Q1KKZ3-1 [UniParc]. Last modified May 30, 2006. Version 1. Checksum: 27A4D4D41F866CE0	FASTA	249	28,169
	10 20 30 40 50 60 MSTLGTSYYA EASVLSEQDE IAPRYPSAAG VEQTMLTEYG GHESCPLQGK STLFAGSWSP 70 80 90 100 110 120 ITTHPPNPGA PTYIHHHYTS GDSDGMFTRS WALDPASLCL TGLPSATMHY EIKPEPLIGS 130 140 150 160 170 180 AECTPLETHT PLLSDIGNDA TIAKIPCEST STDKALKGDK TAEETRERDA NNPSSNWLHA 190 200 210 220 230 240 KPTRKKRCPY TKHQILELEK EFLFNMYLPR DRRYEVARLL HLTERQVKIW FQNRRMKMKK ENKDRRRDS

References

[1]

"Highly conserved syntenic blocks at the vertebrate Hox loci and conserved regulatory elements within and outside Hox gene clusters." Lee A.P., Koh E.G.L., Tay A., Brenner S., Venkatesh B. Proc. Natl. Acad. Sci. U.S.A. 103:6994-6999(2006) [PubMed: 16636282] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].

Cross-references

Sequence databases
EMBLGenBankDDBJ	DQ481664 Genomic DNA. Translation: ABF22401.1.
3D structure databases
SMR	Q1KKZ3. Positions 171-247.
ModBase	Search...
Genome annotation databases
Ensembl	ENSTRUT00000039306; ENSTRUP00000039165; ENSTRUG00000015327; Takifugu rubripes. [Genome view]
Phylogenomic databases
HOVERGEN	Q1KKZ3.
Family and domain databases
InterPro	IPR001356. Homeobox. IPR017970. Homeobox_CS. IPR017112. Homeobox_Hox9. IPR020479. Homeobox_region. IPR009057. Homeodomain-like. IPR012287. Homeodomain-rel. IPR006711. Hox9_act. [Graphical view]
Gene3D	G3DSA:1.10.10.60. Homeodomain-rel. 1 hit.
Pfam	PF00046. Homeobox. 1 hit. PF04617. Hox9_act. 1 hit. [Graphical view]
PIRSF	PIRSF037109. Homeobox_Hox9. 1 hit.
PRINTS	PR00024. HOMEOBOX.
SMART	SM00389. HOX. 1 hit. [Graphical view]
PROSITE	PS00027. HOMEOBOX_1. 1 hit. PS50071. HOMEOBOX_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

HXA9B_TAKRU

Accession

Primary (citable) accession number: Q1KKZ3

Entry history

Integrated into UniProtKB/Swiss-Prot:	December 12, 2006
Last sequence update:	May 30, 2006
Last modified:	November 24, 2009
This is version 22 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)