Reviewed,
UniProtKB/Swiss-Prot Q1KKZ2 (HXA2B_TAKRU)
Last modified
November 24, 2009.
Version 20.
History...
Clusters with 100%,
90%,
50% identity |
Documents (2) |
Third-party data |
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Names and origin
| Protein names | Recommended name: Homeobox protein Hox-A2b | ||
| Gene names |
| ||
| Organism | Takifugu rubripes (Japanese pufferfish) (Fugu rubripes) | ||
| Taxonomic identifier | 31033 [NCBI] | ||
| Taxonomic lineage | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Actinopterygii › Neopterygii › Teleostei › Euteleostei › Neoteleostei › Acanthomorpha › Acanthopterygii › Percomorpha › Tetraodontiformes › Tetradontoidea › Tetraodontidae › Takifugu |
Protein attributes
| Sequence length | 300 AA. |
| Sequence status | Complete. |
| Sequence processing | The displayed sequence is not processed. |
| Protein existence | Inferred from homology. |
General annotation (Comments)
| Function | Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis By similarity. |
| Subcellular location | Nucleus By similarity. |
| Sequence similarities | Belongs to the Antp homeobox family. Proboscipedia subfamily. Contains 1 homeobox DNA-binding domain. |
Ontologies
| Keywords | |
|---|---|
| Biological process | Transcription Transcription regulation |
| Cellular component | Nucleus |
| Domain | Homeobox |
| Ligand | DNA-binding |
| Molecular function | Developmental protein |
| Gene Ontology (GO) | |
| Biological process | multicellular organismal development Inferred from electronic annotation. Source: UniProtKB-KW regulation of transcription, DNA-dependentInferred from electronic annotation. Source: InterPro transcriptionInferred from electronic annotation. Source: UniProtKB-KW |
| Cellular component | nucleus Inferred from electronic annotation. Source: UniProtKB-SubCell |
| Molecular function | sequence-specific DNA binding Inferred from electronic annotation. Source: InterPro transcription factor activityInferred from electronic annotation. Source: InterPro |
| Complete GO annotation... | |
Sequence annotation (Features)
Sequences
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References
| [1] | "Highly conserved syntenic blocks at the vertebrate Hox loci and conserved regulatory elements within and outside Hox gene clusters." Lee A.P., Koh E.G.L., Tay A., Brenner S., Venkatesh B. Proc. Natl. Acad. Sci. U.S.A. 103:6994-6999(2006) [PubMed: 16636282] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]. |
Cross-references
Sequence databases | |
|---|---|
| DQ481664 Genomic DNA. Translation: ABF22402.1. | |
3D structure databases | |
| SMR | Q1KKZ2. Positions 90-146. |
| ModBase | Search... |
Phylogenomic databases | |
| HOVERGEN | Q1KKZ2. |
Family and domain databases | |
| InterPro | IPR001356. Homeobox. IPR017970. Homeobox_CS. IPR020479. Homeobox_region. IPR009057. Homeodomain-like. IPR012287. Homeodomain-rel. [Graphical view] |
| Gene3D | G3DSA:1.10.10.60. Homeodomain-rel. 1 hit. |
| Pfam | PF00046. Homeobox. 1 hit. [Graphical view] |
| PRINTS | PR00024. HOMEOBOX. |
| SMART | SM00389. HOX. 1 hit. [Graphical view] |
| PROSITE | PS00032. ANTENNAPEDIA. False negative. PS00027. HOMEOBOX_1. 1 hit. PS50071. HOMEOBOX_2. 1 hit. [Graphical view] |
| ProtoNet | Search... |
Entry information
| Entry name | HXA2B_TAKRU | ||||||||
| Accession | Primary (citable) accession number: Q1KKZ2 | ||||||||
| Entry history |
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| Entry status | Reviewed (UniProtKB/Swiss-Prot) | ||||||||
Relevant documents
| Vertebrate homeotic Hox proteins Nomenclature of vertebrate homeotic Hox proteins and list of entries |
| SIMILARITY comments Index of protein domains and families |

Clusters with


