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Q1KKX1 (HXB6B_TAKRU) Reviewed, UniProtKB/Swiss-Prot

Last modified June 11, 2014. Version 46. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Protein attributes

Sequence length233 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis By similarity.

Subcellular location

Nucleus By similarity.

Sequence similarities

Belongs to the Antp homeobox family.

Contains 1 homeobox DNA-binding domain.

Ontologies

Keywords
   Biological processTranscription
Transcription regulation
   Cellular componentNucleus
   DomainHomeobox
   LigandDNA-binding
   Molecular functionDevelopmental protein
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Biological_processmulticellular organismal development

Inferred from electronic annotation. Source: UniProtKB-KW

transcription, DNA-templated

Inferred from electronic annotation. Source: UniProtKB-KW

   Cellular_componentnucleus

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionsequence-specific DNA binding

Inferred from electronic annotation. Source: InterPro

sequence-specific DNA binding transcription factor activity

Inferred from electronic annotation. Source: InterPro

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 233233Homeobox protein Hox-B6b
PRO_0000265982

Regions

DNA binding155 – 21460Homeobox
Motif136 – 1416Antp-type hexapeptide

Sequences

Sequence LengthMass (Da)Tools
Q1KKX1 [UniParc].

Last modified May 30, 2006. Version 1.
Checksum: 75414859B5B95018

FASTA23326,629
        10         20         30         40         50         60 
MSSYFVNSTF PVSLPGGQDS LLGQIPLYSS GYTDPLRHYS NAATYGAANM QEKVYPASYY 

        70         80         90        100        110        120 
QQTGAAAIYG RAGGGAPCEY NPVGTFYKET EGSCAFSSRD DQPLFVTQEH QQRKVECPEQ 

       130        140        150        160        170        180 
SVSMGSSIDD KSSTLIYPWM QRMNACSAGP FGNSGRRGRQ TYTRYQTLEL EKEFHFNRYL 

       190        200        210        220        230 
TRRRRIEISH ALCLTERQIK IWFQNRRMKW KKENKLLNPS KTPEEEEEAE KKS 

« Hide

References

[1]"Highly conserved syntenic blocks at the vertebrate Hox loci and conserved regulatory elements within and outside Hox gene clusters."
Lee A.P., Koh E.G.L., Tay A., Brenner S., Venkatesh B.
Proc. Natl. Acad. Sci. U.S.A. 103:6994-6999(2006) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
DQ481666 Genomic DNA. Translation: ABF22423.1.
RefSeqXP_003961127.1. XM_003961078.1.

3D structure databases

ProteinModelPortalQ1KKX1.
SMRQ1KKX1. Positions 156-215.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID101079641.
KEGGtru:101079641.

Organism-specific databases

CTD58053.

Phylogenomic databases

KOK09306.

Family and domain databases

Gene3D1.10.10.60. 1 hit.
InterProIPR017995. Homeobox_antennapedia.
IPR001827. Homeobox_Antennapedia_CS.
IPR017970. Homeobox_CS.
IPR001356. Homeobox_dom.
IPR020479. Homeobox_metazoa.
IPR009057. Homeodomain-like.
[Graphical view]
PfamPF00046. Homeobox. 1 hit.
[Graphical view]
PRINTSPR00025. ANTENNAPEDIA.
PR00024. HOMEOBOX.
SMARTSM00389. HOX. 1 hit.
[Graphical view]
SUPFAMSSF46689. SSF46689. 1 hit.
PROSITEPS00032. ANTENNAPEDIA. 1 hit.
PS00027. HOMEOBOX_1. 1 hit.
PS50071. HOMEOBOX_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameHXB6B_TAKRU
AccessionPrimary (citable) accession number: Q1KKX1
Entry history
Integrated into UniProtKB/Swiss-Prot: December 12, 2006
Last sequence update: May 30, 2006
Last modified: June 11, 2014
This is version 46 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Vertebrate homeotic Hox proteins

Nomenclature of vertebrate homeotic Hox proteins and list of entries