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Q1KKV3 (HXCCA_TAKRU) Reviewed, UniProtKB/Swiss-Prot

Last modified June 11, 2014. Version 59. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Protein attributes

Sequence length275 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis By similarity.

Subcellular location

Nucleus By similarity.

Sequence similarities

Belongs to the Abd-B homeobox family.

Contains 1 homeobox DNA-binding domain.

Ontologies

Keywords
   Biological processTranscription
Transcription regulation
   Cellular componentNucleus
   DomainHomeobox
   LigandDNA-binding
   Molecular functionDevelopmental protein
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Biological_processmulticellular organismal development

Inferred from electronic annotation. Source: UniProtKB-KW

transcription, DNA-templated

Inferred from electronic annotation. Source: UniProtKB-KW

   Cellular_componentnucleus

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionsequence-specific DNA binding

Inferred from electronic annotation. Source: InterPro

sequence-specific DNA binding transcription factor activity

Inferred from electronic annotation. Source: InterPro

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 275275Homeobox protein Hox-C12a
PRO_0000265992

Regions

DNA binding207 – 26660Homeobox

Sequences

Sequence LengthMass (Da)Tools
Q1KKV3 [UniParc].

Last modified May 30, 2006. Version 1.
Checksum: 12774925EB97CAA0

FASTA27530,735
        10         20         30         40         50         60 
MGEHNLLNPG FVGPLVNIHT GDTFYFPNFR PSGGQLPGLP SLSYPRRDNV CSLPWNPSEP 

        70         80         90        100        110        120 
CNGYSQSYFS SPVSINPSFN RSCEITRADD GKCYYNNGSG SRENCSGGGS LKREDRARDT 

       130        140        150        160        170        180 
SALTSDHGMH AGIGSTVAFS KYDYGTEQLT QDPPSCQSME SDSSSSLLNE ASKPSSSDTQ 

       190        200        210        220        230        240 
TLVSPGSHTG TITASGAAPW YPMHTRTRKK RKPYSKLQLA ELEGEFMMNE FITRQRRREL 

       250        260        270 
SDRLNLSDQQ VKIWFQNRRM KKKRLMLREQ ALAYF 

« Hide

References

[1]"Highly conserved syntenic blocks at the vertebrate Hox loci and conserved regulatory elements within and outside Hox gene clusters."
Lee A.P., Koh E.G.L., Tay A., Brenner S., Venkatesh B.
Proc. Natl. Acad. Sci. U.S.A. 103:6994-6999(2006) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
DQ481667 Genomic DNA. Translation: ABF22441.1.
RefSeqXP_003963118.1. XM_003963069.1.

3D structure databases

ProteinModelPortalQ1KKV3.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING31033.ENSTRUP00000010151.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblENSTRUT00000010207; ENSTRUP00000010151; ENSTRUG00000004280.
GeneID101079504.
KEGGtru:101079504.

Phylogenomic databases

eggNOGNOG239684.
GeneTreeENSGT00750000117432.
InParanoidQ1KKV3.
KOK09297.
OMAQDPPSCQ.
OrthoDBEOG7FV3R4.
TreeFamTF351604.

Family and domain databases

Gene3D1.10.10.60. 1 hit.
InterProIPR017970. Homeobox_CS.
IPR001356. Homeobox_dom.
IPR020479. Homeobox_metazoa.
IPR009057. Homeodomain-like.
[Graphical view]
PfamPF00046. Homeobox. 1 hit.
[Graphical view]
PRINTSPR00024. HOMEOBOX.
SMARTSM00389. HOX. 1 hit.
[Graphical view]
SUPFAMSSF46689. SSF46689. 1 hit.
PROSITEPS00027. HOMEOBOX_1. 1 hit.
PS50071. HOMEOBOX_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameHXCCA_TAKRU
AccessionPrimary (citable) accession number: Q1KKV3
Entry history
Integrated into UniProtKB/Swiss-Prot: December 12, 2006
Last sequence update: May 30, 2006
Last modified: June 11, 2014
This is version 59 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Vertebrate homeotic Hox proteins

Nomenclature of vertebrate homeotic Hox proteins and list of entries