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Protein

Homeobox protein Hox-C12a

Gene

hoxc12a

Organism
Takifugu rubripes (Japanese pufferfish) (Fugu rubripes)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.By similarity

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
DNA bindingi207 – 266HomeoboxPROSITE-ProRule annotationAdd BLAST60

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionDevelopmental protein, DNA-binding
Biological processTranscription, Transcription regulation

Names & Taxonomyi

Protein namesi
Recommended name:
Homeobox protein Hox-C12a
Gene namesi
Name:hoxc12a
OrganismiTakifugu rubripes (Japanese pufferfish) (Fugu rubripes)
Taxonomic identifieri31033 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiActinopterygiiNeopterygiiTeleosteiNeoteleosteiAcanthomorphataEupercariaTetraodontiformesTetradontoideaTetraodontidaeTakifugu
Proteomesi
  • UP000005226 Componenti: Unplaced

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002659921 – 275Homeobox protein Hox-C12aAdd BLAST275

Interactioni

Protein-protein interaction databases

STRINGi31033.ENSTRUP00000010151.

Structurei

3D structure databases

ProteinModelPortaliQ1KKV3.
SMRiQ1KKV3.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the Abd-B homeobox family.Curated

Keywords - Domaini

Homeobox

Phylogenomic databases

eggNOGiKOG0487. Eukaryota.
ENOG4111FJP. LUCA.
GeneTreeiENSGT00760000118834.
InParanoidiQ1KKV3.
KOiK09297.
OMAiEPCNGYS.
OrthoDBiEOG091G0HNN.
TreeFamiTF351604.

Family and domain databases

CDDicd00086. homeodomain. 1 hit.
InterProiView protein in InterPro
IPR009057. Homeobox-like.
IPR017970. Homeobox_CS.
IPR001356. Homeobox_dom.
IPR020479. Homeobox_metazoa.
PfamiView protein in Pfam
PF00046. Homeobox. 1 hit.
PRINTSiPR00024. HOMEOBOX.
SMARTiView protein in SMART
SM00389. HOX. 1 hit.
SUPFAMiSSF46689. SSF46689. 1 hit.
PROSITEiView protein in PROSITE
PS00027. HOMEOBOX_1. 1 hit.
PS50071. HOMEOBOX_2. 1 hit.

Sequencei

Sequence statusi: Complete.

Q1KKV3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGEHNLLNPG FVGPLVNIHT GDTFYFPNFR PSGGQLPGLP SLSYPRRDNV
60 70 80 90 100
CSLPWNPSEP CNGYSQSYFS SPVSINPSFN RSCEITRADD GKCYYNNGSG
110 120 130 140 150
SRENCSGGGS LKREDRARDT SALTSDHGMH AGIGSTVAFS KYDYGTEQLT
160 170 180 190 200
QDPPSCQSME SDSSSSLLNE ASKPSSSDTQ TLVSPGSHTG TITASGAAPW
210 220 230 240 250
YPMHTRTRKK RKPYSKLQLA ELEGEFMMNE FITRQRRREL SDRLNLSDQQ
260 270
VKIWFQNRRM KKKRLMLREQ ALAYF
Length:275
Mass (Da):30,735
Last modified:May 30, 2006 - v1
Checksum:i12774925EB97CAA0
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
DQ481667 Genomic DNA. Translation: ABF22441.1.
RefSeqiXP_003963118.1. XM_003963069.2.

Genome annotation databases

EnsembliENSTRUT00000010207; ENSTRUP00000010151; ENSTRUG00000004280.
GeneIDi101079504.
KEGGitru:101079504.

Similar proteinsi

Entry informationi

Entry nameiHXCCA_TAKRU
AccessioniPrimary (citable) accession number: Q1KKV3
Entry historyiIntegrated into UniProtKB/Swiss-Prot: December 12, 2006
Last sequence update: May 30, 2006
Last modified: September 27, 2017
This is version 75 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Vertebrate homeotic Hox proteins
    Nomenclature of vertebrate homeotic Hox proteins and list of entries
  2. SIMILARITY comments
    Index of protein domains and families