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Q1KKT0 (HXDAA_TAKRU) Reviewed, UniProtKB/Swiss-Prot

Last modified June 11, 2014. Version 46. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Protein attributes

Sequence length336 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis By similarity.

Subcellular location

Nucleus By similarity.

Sequence similarities

Belongs to the Abd-B homeobox family.

Contains 1 homeobox DNA-binding domain.

Ontologies

Keywords
   Biological processTranscription
Transcription regulation
   Cellular componentNucleus
   DomainHomeobox
   LigandDNA-binding
   Molecular functionDevelopmental protein
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Biological_processmulticellular organismal development

Inferred from electronic annotation. Source: UniProtKB-KW

transcription, DNA-templated

Inferred from electronic annotation. Source: UniProtKB-KW

   Cellular_componentnucleus

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionsequence-specific DNA binding

Inferred from electronic annotation. Source: InterPro

sequence-specific DNA binding transcription factor activity

Inferred from electronic annotation. Source: InterPro

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 336336Homeobox protein Hox-D10a
PRO_0000265999

Regions

DNA binding262 – 32160Homeobox

Sequences

Sequence LengthMass (Da)Tools
Q1KKT0 [UniParc].

Last modified May 30, 2006. Version 1.
Checksum: 4F666D31642C94FF

FASTA33637,706
        10         20         30         40         50         60 
MSFPSSSPAA NTFLVDSLIS ACRTDSFYTG SSMYMPPGSE MGTYGMQTCG LLPAFSKRGE 

        70         80         90        100        110        120 
VNHQNVGMNV HSYIPQIDNW TDPSRPCRIE SSNQDVQTTH SHQNIKEESN CCMYSDKRVP 

       130        140        150        160        170        180 
KVSSSEVPVY SNVAPESCPV DGPEIPVPGY FRLSQTYATG KHQEPYCHDP PDQSPTLIQL 

       190        200        210        220        230        240 
TPKPQPAPAS ATFADGESEK NKVPPEPATS RTPIQVESPK SATVEKICSP EASASSPELL 

       250        260        270        280        290        300 
QKEGKDSKSD QPANNWLTAK SGRKKRCPYT KHQTLELEKE FLFNMYLTRE RRLEISRSVN 

       310        320        330 
LTDRQVKIWF QNRRMKLKKM SRENRIRELT SNLTFS 

« Hide

References

[1]"Highly conserved syntenic blocks at the vertebrate Hox loci and conserved regulatory elements within and outside Hox gene clusters."
Lee A.P., Koh E.G.L., Tay A., Brenner S., Venkatesh B.
Proc. Natl. Acad. Sci. U.S.A. 103:6994-6999(2006) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
DQ481668 Genomic DNA. Translation: ABF22464.1.

3D structure databases

ProteinModelPortalQ1KKT0.
SMRQ1KKT0. Positions 250-323.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING31033.ENSTRUP00000044927.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Phylogenomic databases

eggNOGNOG274734.

Family and domain databases

Gene3D1.10.10.60. 1 hit.
InterProIPR017970. Homeobox_CS.
IPR001356. Homeobox_dom.
IPR020479. Homeobox_metazoa.
IPR009057. Homeodomain-like.
[Graphical view]
PfamPF00046. Homeobox. 1 hit.
[Graphical view]
PRINTSPR00024. HOMEOBOX.
SMARTSM00389. HOX. 1 hit.
[Graphical view]
SUPFAMSSF46689. SSF46689. 1 hit.
PROSITEPS00027. HOMEOBOX_1. 1 hit.
PS50071. HOMEOBOX_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameHXDAA_TAKRU
AccessionPrimary (citable) accession number: Q1KKT0
Entry history
Integrated into UniProtKB/Swiss-Prot: December 12, 2006
Last sequence update: May 30, 2006
Last modified: June 11, 2014
This is version 46 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Vertebrate homeotic Hox proteins

Nomenclature of vertebrate homeotic Hox proteins and list of entries