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Q1KKS9

- HXD9A_TAKRU

UniProt

Q1KKS9 - HXD9A_TAKRU

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Protein

Homeobox protein Hox-D9a

Gene

hoxd9a

Organism
Takifugu rubripes (Japanese pufferfish) (Fugu rubripes)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.By similarity

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
DNA bindingi205 – 26460HomeoboxPROSITE-ProRule annotationAdd
BLAST

GO - Molecular functioni

  1. sequence-specific DNA binding Source: InterPro

GO - Biological processi

  1. multicellular organismal development Source: UniProtKB-KW
  2. regulation of transcription, DNA-templated Source: UniProtKB-KW
  3. transcription, DNA-templated Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

Developmental protein

Keywords - Biological processi

Transcription, Transcription regulation

Keywords - Ligandi

DNA-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Homeobox protein Hox-D9a
Gene namesi
Name:hoxd9a
OrganismiTakifugu rubripes (Japanese pufferfish) (Fugu rubripes)
Taxonomic identifieri31033 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiActinopterygiiNeopterygiiTeleosteiNeoteleosteiAcanthomorphataEupercariaTetraodontiformesTetradontoideaTetraodontidaeTakifugu
ProteomesiUP000005226: Unplaced

Subcellular locationi

Nucleus PROSITE-ProRule annotation

GO - Cellular componenti

  1. nucleus Source: UniProtKB-KW
Complete GO annotation...

Keywords - Cellular componenti

Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 273273Homeobox protein Hox-D9aPRO_0000265997Add
BLAST

Structurei

3D structure databases

ProteinModelPortaliQ1KKS9.
SMRiQ1KKS9. Positions 193-268.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the Abd-B homeobox family.Curated
Contains 1 homeobox DNA-binding domain.PROSITE-ProRule annotation

Keywords - Domaini

Homeobox

Phylogenomic databases

GeneTreeiENSGT00760000119211.
InParanoidiQ1KKS9.
KOiK09294.

Family and domain databases

Gene3Di1.10.10.60. 1 hit.
InterProiIPR017970. Homeobox_CS.
IPR001356. Homeobox_dom.
IPR017112. Homeobox_Hox9.
IPR020479. Homeobox_metazoa.
IPR009057. Homeodomain-like.
IPR006711. Hox9_activation_N.
[Graphical view]
PfamiPF00046. Homeobox. 1 hit.
PF04617. Hox9_act. 1 hit.
[Graphical view]
PIRSFiPIRSF037109. Homeobox_Hox9. 1 hit.
PRINTSiPR00024. HOMEOBOX.
SMARTiSM00389. HOX. 1 hit.
[Graphical view]
SUPFAMiSSF46689. SSF46689. 1 hit.
PROSITEiPS00027. HOMEOBOX_1. 1 hit.
PS50071. HOMEOBOX_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q1KKS9-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MSRKRSKMST SGPLSNCYVD AIMGQDSEDV YGARYIQAPH MVTPRPSSVG
60 70 80 90 100
DNADFASCNF APKSAVFSSS WSSVHPQGIY HPYVHHHHHH HQSHLPSADG
110 120 130 140 150
RYVGVRSWME PISNHVSFAG LHTSGRSYGT KPEVLPLKDA ECDALEAESR
160 170 180 190 200
PLSAGFVCAA AACPDRARKE HGASELPSHD EHKEEKQQQL DPNNPAANWI
210 220 230 240 250
HARSTRKKRC PYTKYQTLEL EKEFLYNMYL TRDRRYEVAR ILSLTERQVK
260 270
IWFQNRRMKM KKQNRERSGK EHI
Length:273
Mass (Da):31,212
Last modified:May 30, 2006 - v1
Checksum:iC212C93075649967
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
DQ481668 Genomic DNA. Translation: ABF22465.1.
RefSeqiXP_003961878.1. XM_003961829.1.

Genome annotation databases

EnsembliENSTRUT00000045069; ENSTRUP00000044917; ENSTRUG00000017521.
GeneIDi101065047.
KEGGitru:101065047.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
DQ481668 Genomic DNA. Translation: ABF22465.1 .
RefSeqi XP_003961878.1. XM_003961829.1.

3D structure databases

ProteinModelPortali Q1KKS9.
SMRi Q1KKS9. Positions 193-268.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENSTRUT00000045069 ; ENSTRUP00000044917 ; ENSTRUG00000017521 .
GeneIDi 101065047.
KEGGi tru:101065047.

Organism-specific databases

CTDi 30350.

Phylogenomic databases

GeneTreei ENSGT00760000119211.
InParanoidi Q1KKS9.
KOi K09294.

Family and domain databases

Gene3Di 1.10.10.60. 1 hit.
InterProi IPR017970. Homeobox_CS.
IPR001356. Homeobox_dom.
IPR017112. Homeobox_Hox9.
IPR020479. Homeobox_metazoa.
IPR009057. Homeodomain-like.
IPR006711. Hox9_activation_N.
[Graphical view ]
Pfami PF00046. Homeobox. 1 hit.
PF04617. Hox9_act. 1 hit.
[Graphical view ]
PIRSFi PIRSF037109. Homeobox_Hox9. 1 hit.
PRINTSi PR00024. HOMEOBOX.
SMARTi SM00389. HOX. 1 hit.
[Graphical view ]
SUPFAMi SSF46689. SSF46689. 1 hit.
PROSITEi PS00027. HOMEOBOX_1. 1 hit.
PS50071. HOMEOBOX_2. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Highly conserved syntenic blocks at the vertebrate Hox loci and conserved regulatory elements within and outside Hox gene clusters."
    Lee A.P., Koh E.G.L., Tay A., Brenner S., Venkatesh B.
    Proc. Natl. Acad. Sci. U.S.A. 103:6994-6999(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].

Entry informationi

Entry nameiHXD9A_TAKRU
AccessioniPrimary (citable) accession number: Q1KKS9
Entry historyi
Integrated into UniProtKB/Swiss-Prot: December 12, 2006
Last sequence update: May 30, 2006
Last modified: October 29, 2014
This is version 56 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Vertebrate homeotic Hox proteins
    Nomenclature of vertebrate homeotic Hox proteins and list of entries
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3