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Q1KKS2

- CYCB_TAKRU

UniProt

Q1KKS2 - CYCB_TAKRU

Protein

Cytochrome c-b

Gene

cyc-B

Organism
Takifugu rubripes (Japanese pufferfish) (Fugu rubripes)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
  1. Functioni

    Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain By similarity.By similarity

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Binding sitei16 – 161Heme (covalent)PROSITE-ProRule annotation
    Binding sitei19 – 191Heme (covalent)PROSITE-ProRule annotation
    Metal bindingi20 – 201Iron (heme axial ligand)PROSITE-ProRule annotation
    Metal bindingi82 – 821Iron (heme axial ligand)PROSITE-ProRule annotation

    GO - Molecular functioni

    1. electron carrier activity Source: InterPro
    2. heme binding Source: InterPro
    3. iron ion binding Source: InterPro

    GO - Biological processi

    1. oxidation-reduction process Source: UniProtKB-KW

    Keywords - Biological processi

    Electron transport, Respiratory chain, Transport

    Keywords - Ligandi

    Heme, Iron, Metal-binding

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Cytochrome c-b
    Gene namesi
    Name:cyc-B
    OrganismiTakifugu rubripes (Japanese pufferfish) (Fugu rubripes)
    Taxonomic identifieri31033 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiActinopterygiiNeopterygiiTeleosteiNeoteleosteiAcanthomorphataPercomorphariaTetraodontiformesTetradontoideaTetraodontidaeTakifugu
    ProteomesiUP000005226: Unplaced

    Subcellular locationi

    Mitochondrion intermembrane space By similarity
    Note: Loosely associated with the inner membrane.By similarity

    GO - Cellular componenti

    1. mitochondrial intermembrane space Source: UniProtKB-SubCell
    2. respiratory chain Source: UniProtKB-KW

    Keywords - Cellular componenti

    Mitochondrion

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 105105Cytochrome c-bPRO_0000266004Add
    BLAST

    Post-translational modificationi

    Binds 1 heme group per subunit.By similarity

    Proteomic databases

    PRIDEiQ1KKS2.

    Interactioni

    Protein-protein interaction databases

    STRINGi31033.ENSTRUP00000044765.

    Structurei

    3D structure databases

    ProteinModelPortaliQ1KKS2.
    SMRiQ1KKS2. Positions 3-105.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the cytochrome c family.Curated

    Phylogenomic databases

    eggNOGiCOG3474.
    GeneTreeiENSGT00390000009405.
    InParanoidiQ1KKS2.
    KOiK08738.
    OMAiSICASAM.
    OrthoDBiEOG761BWX.
    TreeFamiTF300226.

    Family and domain databases

    Gene3Di1.10.760.10. 1 hit.
    InterProiIPR009056. Cyt_c-like_dom.
    IPR002327. Cyt_c_1A/1B.
    IPR003088. Cyt_c_dom.
    [Graphical view]
    PANTHERiPTHR11961. PTHR11961. 1 hit.
    PfamiPF00034. Cytochrom_C. 1 hit.
    [Graphical view]
    PRINTSiPR00604. CYTCHRMECIAB.
    SUPFAMiSSF46626. SSF46626. 1 hit.
    PROSITEiPS51007. CYTC. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q1KKS2-1 [UniParc]FASTAAdd to Basket

    « Hide

    MSGDIAKGKK AFVQKCAQCH TVEQGGKHKT GPNLWGLFGR KTGQAEGFSY    50
    TDANKSKGII WSEETLMVYL ENPKKYIPGT KMIFAGIKKK TERADLIAYL 100
    KSSTS 105
    Length:105
    Mass (Da):11,575
    Last modified:May 30, 2006 - v1
    Checksum:i4DE3FD6963C7DFB0
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    DQ481668 Genomic DNA. Translation: ABF22472.1.
    RefSeqiXP_003961875.1. XM_003961826.1.

    Genome annotation databases

    EnsembliENSTRUT00000044916; ENSTRUP00000044765; ENSTRUG00000017459.
    GeneIDi101064386.
    KEGGitru:101064386.

    Cross-referencesi

    Web resourcesi

    Protein Spotlight

    Life shuttle - Issue 76 of November 2006

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    DQ481668 Genomic DNA. Translation: ABF22472.1 .
    RefSeqi XP_003961875.1. XM_003961826.1.

    3D structure databases

    ProteinModelPortali Q1KKS2.
    SMRi Q1KKS2. Positions 3-105.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 31033.ENSTRUP00000044765.

    Proteomic databases

    PRIDEi Q1KKS2.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENSTRUT00000044916 ; ENSTRUP00000044765 ; ENSTRUG00000017459 .
    GeneIDi 101064386.
    KEGGi tru:101064386.

    Phylogenomic databases

    eggNOGi COG3474.
    GeneTreei ENSGT00390000009405.
    InParanoidi Q1KKS2.
    KOi K08738.
    OMAi SICASAM.
    OrthoDBi EOG761BWX.
    TreeFami TF300226.

    Family and domain databases

    Gene3Di 1.10.760.10. 1 hit.
    InterProi IPR009056. Cyt_c-like_dom.
    IPR002327. Cyt_c_1A/1B.
    IPR003088. Cyt_c_dom.
    [Graphical view ]
    PANTHERi PTHR11961. PTHR11961. 1 hit.
    Pfami PF00034. Cytochrom_C. 1 hit.
    [Graphical view ]
    PRINTSi PR00604. CYTCHRMECIAB.
    SUPFAMi SSF46626. SSF46626. 1 hit.
    PROSITEi PS51007. CYTC. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Highly conserved syntenic blocks at the vertebrate Hox loci and conserved regulatory elements within and outside Hox gene clusters."
      Lee A.P., Koh E.G.L., Tay A., Brenner S., Venkatesh B.
      Proc. Natl. Acad. Sci. U.S.A. 103:6994-6999(2006) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].

    Entry informationi

    Entry nameiCYCB_TAKRU
    AccessioniPrimary (citable) accession number: Q1KKS2
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: December 12, 2006
    Last sequence update: May 30, 2006
    Last modified: October 1, 2014
    This is version 63 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programChordata Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. Protein Spotlight
      Protein Spotlight articles and cited UniProtKB/Swiss-Prot entries
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3