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Q1JQ92 (POP5_BOVIN) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 49. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Ribonuclease P/MRP protein subunit POP5

EC=3.1.26.5
Gene names
Name:POP5
OrganismBos taurus (Bovine) [Reference proteome]
Taxonomic identifier9913 [NCBI]
Taxonomic lineageEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaCetartiodactylaRuminantiaPecoraBovidaeBovinaeBos

Protein attributes

Sequence length170 AA.
Sequence statusComplete.
Protein existenceEvidence at transcript level

General annotation (Comments)

Function

Component of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends. Also a component of RNase MRP By similarity.

Catalytic activity

Endonucleolytic cleavage of RNA, removing 5'-extranucleotides from tRNA precursor.

Subunit structure

Component of nuclear RNase P and RNase MRP ribonucleoproteins. RNase P consists of an RNA moiety and at least 8 protein subunits; POP1, RPP14, RPP20/POP7, RPP25, RPP29/POP4, RPP30, RPP38 and RPP40. RNase MRP consists of an RNA moiety and at least 9 protein subunits; POP1, RPP14, RPP20/POP7, RPP25, RPP29/POP4, RPP30, RPP38, RPP40, POP5 and RPP21 By similarity.

Subcellular location

Nucleusnucleolus By similarity.

Miscellaneous

The last C-terminal 19 amino acids are not required for complex association and RNase activity.

Sequence similarities

Belongs to the eukaryotic/archaeal RNase P protein component 2 family.

Ontologies

Keywords
   Biological processtRNA processing
   Cellular componentNucleus
   Molecular functionHydrolase
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Biological_processtRNA processing

Inferred from electronic annotation. Source: UniProtKB-KW

   Cellular_componentnucleolus

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionribonuclease P activity

Inferred from electronic annotation. Source: UniProtKB-EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 170170Ribonuclease P/MRP protein subunit POP5
PRO_0000327379

Sequences

Sequence LengthMass (Da)Tools
Q1JQ92 [UniParc].

Last modified June 13, 2006. Version 1.
Checksum: 712668C4F7745A8C

FASTA17019,351
        10         20         30         40         50         60 
MVRFKHRYLL CEVVSDDPRC RLTLEDRVLG TLVRDTIARV HGTFGAAACS IGFAVRYLNA 

        70         80         90        100        110        120 
YTGIVLLRCR KEFYRLVWSA LPFITSLENK GHRYPCFLNT LHVGGTIRTC QKFLIQYNRR 

       130        140        150        160        170 
QLLILLQNCT DEGEREAIQK SVTKSCLLEE ESAGEELSDS GGEETAEPME 

« Hide

References

[1]NIH - Mammalian Gene Collection (MGC) project
Submitted (MAY-2006) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
Strain: Hereford.
Tissue: Fetal cerebellum.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
BC116153 mRNA. Translation: AAI16154.1.
RefSeqNP_001068780.1. NM_001075312.2.
UniGeneBt.10352.

3D structure databases

ProteinModelPortalQ1JQ92.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING9913.ENSBTAP00000007083.

Proteomic databases

PRIDEQ1JQ92.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID507410.
KEGGbta:507410.

Organism-specific databases

CTD51367.

Phylogenomic databases

eggNOGCOG1369.
HOGENOMHOG000293345.
HOVERGENHBG082157.
InParanoidQ1JQ92.
KOK03537.

Family and domain databases

InterProIPR016819. RNase_P/MRP_POP5.
IPR002759. RNase_P/MRP_subunit.
[Graphical view]
PfamPF01900. RNase_P_Rpp14. 1 hit.
[Graphical view]
PIRSFPIRSF023803. Ribonuclease_P_prd. 1 hit.
ProtoNetSearch...

Other

NextBio20868044.

Entry information

Entry namePOP5_BOVIN
AccessionPrimary (citable) accession number: Q1JQ92
Entry history
Integrated into UniProtKB/Swiss-Prot: April 8, 2008
Last sequence update: June 13, 2006
Last modified: April 16, 2014
This is version 49 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families