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Protein
Submitted name:

Si:ch211-284e13.2 protein

Gene

hsd20b2

Organism
Danio rerio (Zebrafish) (Brachydanio rerio)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

  • androstan-3-alpha,17-beta-diol dehydrogenase activity Source: ZFIN

GO - Biological processi

  • multicellular organismal response to stress Source: ZFIN
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
Si:ch211-284e13.2 proteinImported
Gene namesi
Name:hsd20b2Imported
Synonyms:si:ch211-284e13.2Imported
OrganismiDanio rerio (Zebrafish) (Brachydanio rerio)Imported
Taxonomic identifieri7955 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiActinopterygiiNeopterygiiTeleosteiOstariophysiCypriniformesCyprinidaeDanio

Organism-specific databases

ZFINiZDB-GENE-030804-21. hsd20b2.

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei25 – 4319HelicalSequence analysisAdd
BLAST

GO - Cellular componenti

  • endoplasmic reticulum Source: ZFIN
  • integral component of membrane Source: UniProtKB-KW
Complete GO annotation...

Keywords - Cellular componenti

Membrane

PTM / Processingi

Proteomic databases

PaxDbiQ1JQ48.

Interactioni

Protein-protein interaction databases

STRINGi7955.ENSDARP00000091542.

Structurei

3D structure databases

ProteinModelPortaliQ1JQ48.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the short-chain dehydrogenases/reductases (SDR) family.UniRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiKOG1014. Eukaryota.
COG0300. LUCA.
HOGENOMiHOG000039237.
HOVERGENiHBG005478.
PhylomeDBiQ1JQ48.

Family and domain databases

Gene3Di3.40.50.720. 1 hit.
InterProiIPR016040. NAD(P)-bd_dom.
IPR002347. SDR_fam.
[Graphical view]
PANTHERiPTHR24322. PTHR24322. 2 hits.
PfamiPF00106. adh_short. 1 hit.
[Graphical view]
PIRSFiPIRSF000126. 11-beta-HSD1. 1 hit.
PRINTSiPR00081. GDHRDH.
PR00080. SDRFAMILY.
SUPFAMiSSF51735. SSF51735. 1 hit.

Sequencei

Sequence statusi: Fragment.

Q1JQ48-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
IVLFKTVSQK DGVVKKMGDN AECCWYSIVL CGIGCVTVVY YMLRWSWQCW
60 70 80 90 100
HGFKVYVISE IWRTDLRTYG RWAVVTGATS GIGRAYAEEL AKRGLNIVLI
110 120 130 140 150
SRSEEKLHRV SKEIEDKYNQ KTHVIQADFT EGHSIYSTIT KQLEGLEIGI
160 170 180 190 200
LVNNVGMNYI GVLANFLDVP DPDQRITQVL NCNTLSVTQM CRVILPGMVE
210 220 230 240 250
RGKGLIINIS SEAGYQPVPM VSLYSATKAF VTYFSLGLNA EYRSKGITVQ
260 270 280 290 300
CVAPFMVSTN MTHNVPVNPL VKSAASFARD ALNTVGYTTY TSGCLTHALQ
310 320 330 340
HIVLSIVFPG WLRLTSFCVQ RMEKFARRIE PQLNELMAEN KTKQE
Length:345
Mass (Da):38,735
Last modified:June 13, 2006 - v1
Checksum:i7116640F8F13D0EF
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei1 – 11Imported

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC116486 mRNA. Translation: AAI16487.1.
UniGeneiDr.82567.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC116486 mRNA. Translation: AAI16487.1.
UniGeneiDr.82567.

3D structure databases

ProteinModelPortaliQ1JQ48.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi7955.ENSDARP00000091542.

Proteomic databases

PaxDbiQ1JQ48.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Organism-specific databases

ZFINiZDB-GENE-030804-21. hsd20b2.

Phylogenomic databases

eggNOGiKOG1014. Eukaryota.
COG0300. LUCA.
HOGENOMiHOG000039237.
HOVERGENiHBG005478.
PhylomeDBiQ1JQ48.

Family and domain databases

Gene3Di3.40.50.720. 1 hit.
InterProiIPR016040. NAD(P)-bd_dom.
IPR002347. SDR_fam.
[Graphical view]
PANTHERiPTHR24322. PTHR24322. 2 hits.
PfamiPF00106. adh_short. 1 hit.
[Graphical view]
PIRSFiPIRSF000126. 11-beta-HSD1. 1 hit.
PRINTSiPR00081. GDHRDH.
PR00080. SDRFAMILY.
SUPFAMiSSF51735. SSF51735. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. NIH - Zebrafish Gene Collection (ZGC) project
    Submitted (MAY-2006) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Tissue: EmbryoImported.

Entry informationi

Entry nameiQ1JQ48_DANRE
AccessioniPrimary (citable) accession number: Q1JQ48
Entry historyi
Integrated into UniProtKB/TrEMBL: June 13, 2006
Last sequence update: June 13, 2006
Last modified: July 6, 2016
This is version 66 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.