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Q1JP59 (Q1JP59_STRPC) Unreviewed, UniProtKB/TrEMBL

Last modified April 16, 2014. Version 64. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
DNA polymerase III subunit beta PIRNR PIRNR000804

EC=2.7.7.7 PIRNR PIRNR000804
Gene names
Name:dnaN EMBL ABF31190.1
Ordered Locus Names:MGAS9429_Spy0002 EMBL ABF31190.1
OrganismStreptococcus pyogenes serotype M12 (strain MGAS9429) [Complete proteome] [HAMAP] EMBL ABF31190.1
Taxonomic identifier370551 [NCBI]
Taxonomic lineageBacteriaFirmicutesBacilliLactobacillalesStreptococcaceaeStreptococcus

Protein attributes

Sequence length378 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP-independent) along duplex DNA By similarity. PIRNR PIRNR000804

Catalytic activity

Deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1). PIRNR PIRNR000804 SAAS SAAS022635

Subcellular location

Cytoplasm By similarity PIRNR PIRNR000804 SAAS SAAS022635.

Sequences

Sequence LengthMass (Da)Tools
Q1JP59 [UniParc].

Last modified June 13, 2006. Version 1.
Checksum: 2B7791E598C8A86C

FASTA37841,855
        10         20         30         40         50         60 
MIQFSINRTL FIHALNATKR AISTKNAIPI LSSIKIEVTS TGVTLTGSNG QISIENTIPV 

        70         80         90        100        110        120 
SNENAGLLIT SPGAILLEAS FFINIISSLP DISINVKEIE QHQVVLTSGK SEITLKGKDV 

       130        140        150        160        170        180 
DQYPRLQEVS TENPLILKTK LLKSIIAETA FAASLQESRP ILTGVHIVLS NHKDFKAVAT 

       190        200        210        220        230        240 
DSHRMSQRLI TLDNTSADFD VVIPSKSLRE FSAVFTDDIE TVEVFFSPSQ ILFRSEHISF 

       250        260        270        280        290        300 
YTRLLEGNYP DTDRLLMTEF ETEVVFNTQS LRHAMERAFL ISNATQNGTV KLEITQNHIS 

       310        320        330        340        350        360 
AHVNSPEVGK VNEDLDIVSQ SGSDLTISFN PTYLIESLKA IKSETVKIHF LSPVRPFTLT 

       370 
PGDEEESFIQ LITPVRTN 

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References

[1]"Molecular genetic anatomy of inter- and intraserotype variation in the human bacterial pathogen group A Streptococcus."
Beres S.B., Richter E.W., Nagiec M.J., Sumby P., Porcella S.F., DeLeo F.R., Musser J.M.
Proc. Natl. Acad. Sci. U.S.A. 103:7059-7064(2006) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: MGAS9429 EMBL ABF31190.1.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP000259 Genomic DNA. Translation: ABF31190.1.
RefSeqYP_595734.1. NC_008021.1.

3D structure databases

ProteinModelPortalQ1JP59.
SMRQ1JP59. Positions 1-377.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING370551.MGAS9429_Spy0002.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaABF31190; ABF31190; MGAS9429_Spy0002.
GeneID4061523.
KEGGspk:MGAS9429_Spy0002.
PATRIC19750900. VBIStrPyo37061_0002.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0592.
HOGENOMHOG000071792.
KOK02338.
OMADYNRVIP.
OrthoDBEOG65J53F.
ProtClustDBPRK05643.

Enzyme and pathway databases

BioCycSPYO370551:GHLY-2-MONOMER.

Family and domain databases

InterProIPR001001. DNA_polIII_beta.
IPR022635. DNA_polIII_beta_C.
IPR022637. DNA_polIII_beta_cen.
IPR022634. DNA_polIII_beta_N.
[Graphical view]
PfamPF00712. DNA_pol3_beta. 1 hit.
PF02767. DNA_pol3_beta_2. 1 hit.
PF02768. DNA_pol3_beta_3. 1 hit.
[Graphical view]
PIRSFPIRSF000804. DNA_pol_III_b. 1 hit.
SMARTSM00480. POL3Bc. 1 hit.
[Graphical view]
TIGRFAMsTIGR00663. dnan. 1 hit.
ProtoNetSearch...

Entry information

Entry nameQ1JP59_STRPC
AccessionPrimary (citable) accession number: Q1JP59
Entry history
Integrated into UniProtKB/TrEMBL: June 13, 2006
Last sequence update: June 13, 2006
Last modified: April 16, 2014
This is version 64 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)