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Q1JMR6 (Q1JMR6_STRPC) Unreviewed, UniProtKB/TrEMBL

Last modified February 19, 2014. Version 56. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry infoCustomize order

Names and origin

Protein namesRecommended name:
Phosphoenolpyruvate carboxylase HAMAP-Rule MF_00595

Short name=PEPC HAMAP-Rule MF_00595
Short name=PEPCase HAMAP-Rule MF_00595
EC=4.1.1.31 HAMAP-Rule MF_00595
Gene names
Name:ppc HAMAP-Rule MF_00595 EMBL ABF31683.1
Ordered Locus Names:MGAS9429_Spy0495 EMBL ABF31683.1
OrganismStreptococcus pyogenes serotype M12 (strain MGAS9429) [Complete proteome] [HAMAP] EMBL ABF31683.1
Taxonomic identifier370551 [NCBI]
Taxonomic lineageBacteriaFirmicutesBacilliLactobacillalesStreptococcaceaeStreptococcus

Protein attributes

Sequence length937 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle By similarity. HAMAP-Rule MF_00595

Catalytic activity

Phosphate + oxaloacetate = H2O + phosphoenolpyruvate + HCO3-. HAMAP-Rule MF_00595 SAAS SAAS021135

Cofactor

Magnesium By similarity. HAMAP-Rule MF_00595 SAAS SAAS021135

Subunit structure

Homotetramer By similarity. HAMAP-Rule MF_00595

Sequence similarities

Belongs to the PEPCase type 1 family. HAMAP-Rule MF_00595

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Sites

Active site1551 By similarity HAMAP-Rule MF_00595
Active site6001 By similarity HAMAP-Rule MF_00595

Sequences

Sequence LengthMass (Da)Tools
Q1JMR6 [UniParc].

Last modified June 13, 2006. Version 1.
Checksum: 91E9B04033B33606

FASTA937106,495
        10         20         30         40         50         60 
MVKSGMIEET SKEGDGHLPL KKLESSNNQA IIAEEVALLK EMLENITRRM IGDDAFTVIE 

        70         80         90        100        110        120 
SIMVLSEKQD YIELEKVVAN ISNQEMEVIS RYFSILPLLI NISEDVDLAY EINYQNNTDT 

       130        140        150        160        170        180 
DYLGKLALTI KDLAGKDNGK DILEQVNVVP VLTAHPTQVQ RKTILELTTH IHKLLRKYRD 

       190        200        210        220        230        240 
AKAGVINLEK WRQELYRYIE MIMQTDIIRE KKLQVKNEIK NVMQYYDGSL IQAVTKLTTE 

       250        260        270        280        290        300 
YKNLAQKHGL ELDNPKPITM GMWIGGDRDG NPFVTAETLC LSATVQSEVI LNYYIDKLAA 

       310        320        330        340        350        360 
LYRTFSLSST LVQPNSEVER LASLSQDQSI YRGNEPYRRA FHYIQSRLKQ TQNQLTNQPA 

       370        380        390        400        410        420 
ARMSSSVGLN TSAWSSPASL ENPILAYDSP VDFKADLKAI EQSLLDNGNS ALIEGDLREV 

       430        440        450        460        470        480 
MQAVDIFGFF LASIDMRQDS SVQEACVAEL LKGANIVDDY SSLSETEKCD VLLQQLMEEP 

       490        500        510        520        530        540 
RTLSSAAVAK SDLLEKELAI YTTARELKDK LGEEVIKQHI ISHTESVSDM FELAIMLKEV 

       550        560        570        580        590        600 
GLVDQQRARV QIVPLFETIE DLDNARDIMA AYLSHDIVKS WIATNRNYQE IMLGYSDSNK 

       610        620        630        640        650        660 
DGGYLASGWT LYKAQNELTA IGEEHGVKIT FFHGRGGTVG RGGGPSYDAI TSQPFGSIKD 

       670        680        690        700        710        720 
RIRLTEQGEI IENKYGNKDV AYYHLEMLIS ASINRMVTQM ITDPNEIDSF REIMDSIVAD 

       730        740        750        760        770        780 
SNTIYRKLVF DNPHFYDYFF EASPIKEVSS LNIGSRPAAR KTITEITGLR AIPWVFSWSQ 

       790        800        810        820        830        840 
NRIMFPGWYG VGSAFKRYID RAQGNLERLQ HMYQTWPFFH SLLSNVDMVL SKSNMNIAFQ 

       850        860        870        880        890        900 
YAQLAESQDV RDVFYEILDE WQLTKNVILA IQDHDDLLED NPSLKHSLKS RLPYFNVLNY 

       910        920        930 
IQIELIKRWR NNQLDENDEK LIHTTINGIA TGLRNSG 

« Hide

References

[1]"Molecular genetic anatomy of inter- and intraserotype variation in the human bacterial pathogen group A Streptococcus."
Beres S.B., Richter E.W., Nagiec M.J., Sumby P., Porcella S.F., DeLeo F.R., Musser J.M.
Proc. Natl. Acad. Sci. U.S.A. 103:7059-7064(2006) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: MGAS9429 EMBL ABF31683.1.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP000259 Genomic DNA. Translation: ABF31683.1.
RefSeqYP_596227.1. NC_008021.1.

3D structure databases

ProteinModelPortalQ1JMR6.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING370551.MGAS9429_Spy0495.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaABF31683; ABF31683; MGAS9429_Spy0495.
GeneID4062032.
KEGGspk:MGAS9429_Spy0495.
PATRIC19752024. VBIStrPyo37061_0508.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG2352.
HOGENOMHOG000238647.
KOK01595.
OMAAIPWVFG.
OrthoDBEOG6TJ7T8.
ProtClustDBPRK00009.

Enzyme and pathway databases

BioCycSPYO370551:GHLY-551-MONOMER.

Family and domain databases

HAMAPMF_00595. PEPcase_type1.
InterProIPR021135. PEP_COase.
IPR018129. PEP_COase_AS.
IPR022805. PEP_COase_bac/pln-type.
IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
[Graphical view]
PfamPF00311. PEPcase. 1 hit.
[Graphical view]
PRINTSPR00150. PEPCARBXLASE.
SUPFAMSSF51621. SSF51621. 1 hit.
PROSITEPS00781. PEPCASE_1. 1 hit.
PS00393. PEPCASE_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameQ1JMR6_STRPC
AccessionPrimary (citable) accession number: Q1JMR6
Entry history
Integrated into UniProtKB/TrEMBL: June 13, 2006
Last sequence update: June 13, 2006
Last modified: February 19, 2014
This is version 56 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)