Q1JM10 (Q1JM10_STRPC) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Hyaluronate lyase EMBL ABF32059.1
EC=4.2.2.1 EMBL ABF32059.1

Gene names

Name:	hylA EMBL ABF32059.1
Ordered Locus Names:	MGAS9429_Spy0871

Organism

Streptococcus pyogenes serotype M12 (strain MGAS9429) [Complete proteome] [HAMAP] EMBL ABF32059.1

Taxonomic identifier

370551 [NCBI]

Taxonomic lineage

Bacteria › Firmicutes › Lactobacillales › Streptococcaceae › Streptococcus

Protein attributes

Sequence length	828 AA.
Sequence status	Complete.
Protein existence	Predicted

Ontologies

Keywords
Molecular function	Lyase EMBL ABF32059.1
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	carbohydrate metabolic process Inferred from electronic annotation. Source: InterPro
Cellular component	extracellular region Inferred from electronic annotation. Source: InterPro
Molecular function	carbohydrate binding Inferred from electronic annotation. Source: InterPro hyaluronate lyase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q1JM10 [UniParc]. Last modified June 13, 2006. Version 1. Checksum: 8592EA6A08C52D22	FASTA	828	95,351
	10 20 30 40 50 60 MVYFYLVNQS TFIISFLYWR NLSVNTYFCT HHKQLLLYSN LFLSFAMMGQ GTAIYADTLT 70 80 90 100 110 120 SNSEPNNTYF QTQTLTTTDS EKKVVQPQQK DYYTELLDQW NSIIAGNDAY VKTNPDMVTF 130 140 150 160 170 180 HNKAEKDAQN IIKSYQGPDH ENRTYLWEHA KDYSASTNIT KTYRNIEKIA KQITNPESCY 190 200 210 220 230 240 YQDSKAIAIV KDGMAFMYEH AYNLNRENHQ TTGKENKENW WVYEIGTPRA INNTLSLMYP 250 260 270 280 290 300 YFTQEEILKY TAPIEKFVPD PTRFRVRAAN FSPFEASSGN LIDMGRVKLI SGILRKDDLE 310 320 330 340 350 360 ISDTIKAIEK VFTLVDEGNG FYQDGSLIDH VVTNAQSPLY KKGIAYTGAY GNVLIDGLSQ 370 380 390 400 410 420 LIPIIQKTKS PIEADKMATI YHWINHSFFP IIVRGEMMDM TRGRSISRFN AQSHVAGIEA 430 440 450 460 470 480 LRAILRIADM SEEPHRLALK TRIKTLVTQG NAFYNVYDNL KTYHDIKLMK ELLSDTSVPV 490 500 510 520 530 540 QKLDSYVASF NSMDKLALYN NKHDFAFGLS MFSNRTQNYE AMNNENLHGW FTSDGMFYLY 550 560 570 580 590 600 NNDLGHYSEN YWATVNPYRL PGTTETEQKP LEGTPENIKT NYQQVGMTSL SDDAFVASKK 610 620 630 640 650 660 LNNTSALAAM TFTNWNKSLT LNKGWFILGN KIIFVGSNIK NQSSHKAYTT IEQRKENQKH 670 680 690 700 710 720 PYCSYVNNQP VDLNNQLVDF TNTKSIFLES DDPAQNIGYY FFKPTTLSIS KALQTGKWQN 730 740 750 760 770 780 IKADDKSPEA IKEVSNTFIT IMQNHTQDGD RYAYMMLPNM TRQEFETYIS KLDIDLLENN 790 800 810 820 DKLAAVYDHD SQQMHVIHYE KKATMFSNHN LSHQGFYSFP HPVKQNQQ

References

[1]

"Molecular genetic anatomy of inter- and intraserotype variation in the human bacterial pathogen group A Streptococcus." Beres S.B., Richter E.W., Nagiec M.J., Sumby P., Porcella S.F., DeLeo F.R., Musser J.M. Proc. Natl. Acad. Sci. U.S.A. 103:7059-7064(2006) [PubMed: 16636287] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000259 Genomic DNA. Translation: ABF32059.1.
RefSeq	YP_596603.1. NC_008021.1.
3D structure databases
ProteinModelPortal	Q1JM10.
SMR	Q1JM10. Positions 90-803.
ModBase	Search...
Protein-protein interaction databases
STRING	Q1JM10.
Protein family/group databases
CAZy	PL8. Polysaccharide Lyase Family 8.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	EBSTRT00000046206; EBSTRP00000044423; EBSTRG00000046198.
GeneID	4062348.
GenomeReviews	Gene locus MGAS9429_Spy0871 in contig CP000259_GR.
KEGG	spk:MGAS9429_Spy0871.
PATRIC	19752795. VBIStrPyo37061_0889.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	NOG04835.
GeneTree	EBGT00050000027679.
HOGENOM	HBG698564.
OMA	TKTYRNI.
ProtClustDB	CLSK442844.
Enzyme and pathway databases
BioCyc	SPYO370551:MGAS9429_SPY0871-MONOMER.
Family and domain databases
InterPro	IPR008929. Chondroitin_lyas. IPR011013. Glyco_hydro-type_carb-bd. IPR014718. Glyco_hydro-type_carb-bd_sub. IPR012970. Lyase_8_alpha_N. IPR004103. Lyase_8_C. IPR003159. Lyase_8_central_dom. IPR012329. Lyase_8_N. [Graphical view]
Gene3D	G3DSA:2.70.98.10. Glyco_hydro_42_D5. 1 hit. G3DSA:2.60.220.10. Lyase_8_C. 1 hit. G3DSA:1.50.10.100. Lyase_8_N. 1 hit.
KO	K01727.
Pfam	PF02278. Lyase_8. 1 hit. PF08124. Lyase_8_N. 1 hit. [Graphical view]
SUPFAM	SSF48230. Chondroitin_lyas. 1 hit. SSF74650. Gal_mut_like. 1 hit.
ProtoNet	Search...

Entry information

Entry name

Q1JM10_STRPC

Accession

Primary (citable) accession number: Q1JM10

Entry history

Integrated into UniProtKB/TrEMBL:	June 13, 2006
Last sequence update:	June 13, 2006
Last modified:	December 14, 2011
This is version 37 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)